Free admission 16th May – 18th



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FREE ADMISSION
16th May – 18th May 2018

International Hepatitis Symposium Heidelberg

Ralf Bartenschlager’s 60th Birthday Symposium (16th)

AND

International Symposium of the TRR179 (17th to 18th)

Conference Venue: DKFZ Heidelberg

Confirmed Speakers:

Andrea Ablasser, Lausanne

Andreas Bergthaler, Vienna

Eva Billerbeck, New York

Maura Dandri, Hamburg

Carlo Ferrari, Parma

Markus Heim, Basel

Matteo Iannacone, Milan

Stanley M. Lemon, Chapel Hill

Wenhui Li, Peking

Mala Maini, London

Darius Moradpour, Lausanne

Christine Neuveut, Paris

Thomas Pietschmann, Hannover

Barbara Rehermann, Bethesda

Charles M. Rice, New York

Naglaa Shoukry, Montreal

John E. Wherry, Philadelphia



Adam Zlotnick, Bloomington

Please register at http://www.trr179.de/en/news/symposium until 15th April 18

Ralf Bartenschlager’s 60th Birthday Symposium
Symposium Chair:

PD Dr. Volker Lohmann

Department of Infectious Diseases, Molecular Virology,

Heidelberg University Hospital;


International Symposium of the TRR179

Symposium Chairs:

Prof. Dr. Ralf Bartenschlager

Department of Infectious Diseases, Molecular Virology,

Heidelberg University Hospital;

Research Division ‘Virus-associated Carcinogenesis’,

German Cancer Research Center Heidelberg;

German Centre for Infection Research (DZIF e.V.)


Prof. Dr. Robert Thimme

Department of Internal Medicine II,

University Hospital Freiburg
Prof. Dr. Ulrike Protzer

Institute of Virology,

TU München/ Helmholtz Zentrum München;

German Centre for Infection Research (DZIF e.V.)







Organizing Committee:

PD Dr. Volker Lohmann

Dr. Sandra Bühler

Dr. Catherine Moreau

Steffi Schimang


Organizing Committee:

Prof. Dr. Ralf Bartenschlager

Prof. Dr. Robert Thimme

Prof. Dr. Ulrike Protzer

Dr. Sandra Bühler

Dr. Catherine Moreau

Steffi Schimang


Conference Language:

The conference language will be English.


Registration: Admission free! Please register until 15th April 2018

http://www.trr179.de/en/news/symposium/


Contact:

Dr. Sandra Bühler or Steffi Schimang, Department of Infectious Diseases, Molecular Virology, Im Neuenheimer Feld 344, 69120 Heidelberg

Tel.: +49 6221 56 7895 or 7598
AGENDA Ralf Bartenschlager’s 60th Birthday Symposium

Wednesday, 16th May 2018

10:00 Welcome addresses

11:00 Darius Moradpour, Lausanne, Switzerland


11:45 – 13:00 LUNCH

Foyer DKFZ Communication Center


13:00 Michael Nassal, Freiburg, Germany

13:20 Ursula Klingmüller, Heidelberg, Germany

13:40 tba

14:00 Rene Devos, St. Albans, United Kingdom

14:20 Matthias Reddehase, Mainz, Germany

14:40 Thomas Pietschmann, Hannover, Germany

15:00 David Paul, Cambridge, United Kingdom



15:30 – 16:00 COFFEE BREAK

Foyer DKFZ Communication Center

16:00 Laurent Chatel-Chaix, Montreal, Canada

16:20 Marco Binder, Heidelberg, Germany

16:40 Stefan Seitz, Heidelberg, Germany

17:00 Mathias Heikenwälder, München and Heidelberg, Germany

17:20 Stephan Urban, Heidelberg, Germany

17:40 Charles Rice, New York, USA



18:15- 20:30 TRR179 Welcome Reception

Foyer DKFZ Communication Center

r


AGENDA International Symposium of the TRR179

Thursday, 17th May 2018

09:00 Welcome address



Ralf Bartenschlager

Inflammation and Microbiome

Chairman: Hartmut Hengel

09:20 Role of microbiota in host fitness



Barbara Rehermann, Bethesda, USA

09:45 Hepatic metabolism directs antiviral immunity in persistent infection



Andreas Bergthaler, Vienna, Austria

10:10 Lymphotoxin β receptor signalling-dependent control of virus clearance in chronic hepatitis B virus and hepatitis C virus infections



Mathias Heikenwälder TRR179


10:25– 10:50 COFFEE BREAK

Foyer DKFZ Communication Center


Innate Immune Response

Chairman: Andreas Pichlmair

10:50 Intracellular DNA sensing strategies



Andrea Ablasser, Lausanne, Switzerland

11:15 Dissecting NK cell-mediated immune responses against hepatitis B virus and hepatitis C virus infection



Adelheid Cerwenka TRR179

11:30 Mechanisms of interferon induction by hepatitis D virus and impact of chronic innate immune activation on antiviral immunity



Veit Hornung/Percy Knolle TRR179

11:45 Strategies to harness an effective antiviral response targeting hepatitis B virus



Ursula Klingmüller/Jens Timmer TRR179

12:00 Global effects on host cell signalling by continuous stimulation of innate antiviral responses in persistent viral infections



Marco Binder/Andreas Pichlmair TRR179

12:15 Role of innate immune response in HCV infection



Markus Heim, Basel, Switzerland


12:45 – 13:45 LUNCH

Foyer DKFZ Communication Center


In Vivo Imaging and Mouse Models

Chairman: Percy Knolle

13:45 Pathogenetic mechanisms underlying liver immunopathology during viral hepatitis



Matteo Iannacone, Milan, Italy

14:10 Molecular mechanisms of HBV and HDV persistence



Maura Dandri, Hamburg, Germany

14:35 Dynamics of antiviral T cell immunity against viral infection of the liver



Dirk Wohlleber/Vasilis Ntziachristos TRR179

14:50 Mouse models of acute and chronis hepacivirus infection



Eva Billerbeck, New York, USA

Cell biology of hepatitis virus replication

Chairman: Dirk Grimm

15:15 Unravelling the role of DNA repair in the formation of the hepatitis B virus cccDNA persistence reservoir



Sabrina Schreiner/Michael Nassal TRR179

15:30 Contribution of innate immune response to persistence versus clearance of hepatitis C virus and hepatitis A virus infections



Volker Lohmann TRR179

15:45 tba



Alessia Ruggieri TRR179

16:00 Means of modification and degradation of hepatitis B virus cccDNA



Ulrike Protzer/ Dirk Grimm TRR179


16:15 – 16:45 COFFEE BREAK

Foyer DKFZ Communication Center


Chairman: Michael Nassal

16:45 Highjacking of cell regulation by HBV : a 3D nuclear perspective



Christine Neuveut, Paris, France

17:10 Assembly and Misassembly of HBV capsids



Adam Zlotnick, Bloomington, USA

17:35 Determinants of success and failure to control hepatitis C virus infection by the interferon system



Ralf Bartenschlager TRR179

17:50 Hepatitis B virus X-protein-mediated transcriptional regulation and stability of cccDNA



Stephan Urban TRR179

18:05 HBV entry



Wenhui Li, Peking, China

18:30 Cellular egress and entry of quasi-enveloped hepatitis A virus



Stanley M. Lemon, Chapel Hill, USA


19:00 – SPEAKERS’ DINNER

Castle Schriesheim – Bus transfer


Friday, 18th May 2018

Adaptive Immune Response

Chairman: Robert Thimme

09:15 T cell exhaustion in chronic HBV infection or T cell exhaustion in chronic HBV infection and potential correction strategies



Carlo Ferrari, Parma

09:40 Protective immunity against HCV, insights from reinfection studies



Naglaa Shoukry, Montreal, Canada; Cooperation CanHepc

10:05 Characterization of follicular T helper cell responses in viral hepatitis



Tobias Böttler TRR179

10:20 Heterogeneity of HBV- and HCV-specific CD8+ T cells in chronic infection



Maike Hofmann/Robert Thimme TRR179

10:35 Role of myeloid cells in the liver for antiviral immunity



Percy Knolle TRR179

10:50 Viral escape from dominant virus-specific CD8+ T cell responses in hepatitis B virus (HBV) mono-infection and HBV/hepatitis D virus co-infection and strategies to restore antiviral CD8+ T cell response



Christoph Neumann-Häfelin TRR179


10:50 – 11:20 COFFEE BREAK

Foyer DKFZ Communication Center

11:20 Immune correlates of viral persistence and liver damage



Mala Maini, London

11:45 T-cell exhaustion



John E. Wherry, Philadelphia

12:10 Farewell



Ralf Bartenschlager, Robert Thimme and Ulrike Protzer


12:15– LUNCH FOR TAKE AWAY

Foyer DKFZ Communication Center



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