Name of journal: World Journal of Methodology esps manuscript no: 7544 Columns: review adult stem cell-based apexogenesis



Download 109.24 Kb.
Page3/3
Date conversion26.11.2016
Size109.24 Kb.
1   2   3

L-Editor: E-Editor:
Figure 1 Stem cells have the capacity of self-renewal and multiple-differentiation.

Table 1 Adult stem cell candidates





BMMSCs

DPSCs

SCAPs

SHEDs

PDLSCs

DFPCs

Location

Bone marrow

Permanent tooth pulp

Apical papilla of

developing root



Exfoliated deciduous

tooth pulp



Periodontal ligament

Dental follicle

Specific markers

ND

ND

CD24

ND

ND

GoPro49

Proliferation rate

Moderate

Higher

Higher

Higher

Higher

Higher

Multi-potentiality

Odontoblast, osteoblast, adipocyte, chondrocyte, myocyte, neurocyte,

tenocyte



Odontoblast, osteoblast, adipocyte, chondrocyte, myocyte, neurocyte

Odontoblast, osteoblast, adipocyte, chondrocyte,

neurocyte



Odontoblast, osteoblast,

adipocyte, chondrocyte, myocyte, neurocyte



Osteoblast, chondrocyte,

adipocyte, neurocyte,

cementoblasts


Osteoblasts, chondrocytes, cementoblasts, adipocytes,

PDL fibroblasts,

neuron-like cells


In vivo transplantation

Dentin-pulp-like tissue,

bone,


cementum,

PDL


Dentin-pulp complex,

bone


Dentin-pulp-like complex,

bone


Dentin-like tissue,

bone


Cementum/PDL-like structure

Cementum-like structure,

bone


ND: Not determined; BMMSCs: Bone marrow mesenchymal stem cells; DPSCs: dental pulp stem cells; SCAPs: Stem cells from apical papilla; SHEDs: Stem cells from human exfoliated deciduous teeth.

Table 2 Comparison of in vivo transplantation outcomes of mesenchymal stem cells from different reseachers

Ref.

MSCs

Outcomes

Ohazama et al[42]

BMMSCs

Tooth structures and associated bone

Li et al[28]

BMMSCs

Tooth-like structures surrounded by bone and soft tissues

Kawaguchi et al[43]

BMMSCs

Histologically produced cementum, periodontal ligament (PDL), and alveolar bone

Gronthos et al[44]

DPSCs

Pulp-dentine like tissue complexes lined with odontoblast-like cells

Papaccio et al[42]

DPSCs

Bone-like tissues

Sonoyama et al[49]

SCAPs

A typical dentin structure with connective tissues

Battula et al[39]

Miura et al[53]



SCAPs

SHEDs


Bone-/dentin-like mineralized tissues

Dentin-like tissue, but not a dentin-pulp-like complex; not differentiate directly into osteoblasts but only induce new bone formation



Wang et al[55]

SHEDs

Exhibit an enhanced potential to form bone

Park et al[56]/ Seo et al[58]

PDLSCs

A typical cementum/PDL-like structure

Morsczeck et al[60]

DFPCs

A structure consists of fibrous or rigid tissue, no dentin, cementum, or bone formation

Handa et al[65]

DFPCs

Cementum-like matrix

Honda et al[66]

DFPCs

Bone

MSCs: Mesenchymal stem cells.


1   2   3


The database is protected by copyright ©dentisty.org 2016
send message

    Main page