Be able to describe the relationship of actin and Myosin to myofibrils, muscle fibers and muscle group. How can the activation of a skeletal muscle produce movement?
How does the activation of an alpha motor neuron lead to muscle contraction? What is the end-plate potential and how is it different from an EPSP? What is the role of Ca++ in muscle contraction? What is the sarcolemma?
What are the characteristics of Myasthenia Gravis? What is the nature of this disease and what are the effects. How do recordings of neuromuscular tetanizing stimulation help reveal MG?
What are spinal reflex arcs? What is the difference between a monosynaptic and a polysynaptic reflex arc? Be able to describe the “simple stretch reflex.” Describe the withdrawal reflex arc. What is the difference between extrafuscal and intrafuscal muscle fiber? What is the neuromuscular “spindle?” What role does it play in the stretch reflex?
Why is the idea of a monosynaptic reflex arc artificial?
How do the concepts of agonist, antagonist and synergistic muscle groups relate to the question above? What is meant by the idea of poly-segmental reflex arcs? Of “cross-segmental” reflex arcs?
What is the Golgi tendon Organ? What role does it play in spinal reflex arcs? What is a renshaw cell? Why is it important?
If we have time to see the film I’ve selected then you should also be able to answer the following questions: What is encephalitis lethargic?
What name was this disease commonly given?
What happened to most of those who survived this disease?
How would you describe the syndromes that existed in these survivors?
What did Oliver Sachs do in efforts to help these people?
Was his intervention ultimately successful? ….Why or why not?