Multiple choice questions

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DENT5315/DH2215 NAME: ____________________________

Oral Histology/Embryology/Genetics

EXAM 1 (February 5th 2008) ID#: ________________

MULTIPLE CHOICE QUESTIONS. Choose ONE BEST answer for each of the following questions. CAUTION: Read all questions carefully!

1. All of the following are major sites of hematopoiesis EXCEPT the

A. Outer layer of the yolk sac wall

B. Spleen

C. Liver

D. Kidney*

2. When considering the pattern of SENSORY innervation of the tongue, the 1st and the 3rd branchial arch are involved in the development of the tongue:

      1. True*

B. False
3. The muscles of the limbs are derived from:

A. Neural crest mesenchyme

B. Splanchnopleuric mesoderm

C. Intermediate plate mesoderm

D. Paraxial mesoderm*

E. Somatopleuric mesoderm

4. Which of the following papillae contain taste buds:

1. Filiform

2. Circumvallate

3. Fungiform

4. Foliate
A. 1, 2 and 4

B. 1, 2 and 3

C. 1, 3 and 4

D. 2, 3 and 4*

5. Abnormalities of the Thymus indicate abnormal development of which of the following pharyngeal pouches?

A. 1st only

B. 1st and 2nd

C. 2nd and 3rd

D. 3rd only*

E. 3rd and 4th

6. Mucoperiosteum refers to tissue in which the lamina propria is directly attached to the periosteum that covers the bone:

A. True*

B. False
7. Which of the following statements concerning the otic vesicle is correct?
A. It develops from the ectoderm*
B. It is found adjacent to the forebrain
C. It gives rise to the auditory meatus
D. It gives rise to the tympanic membrane

8. The following statements are true about the tongue EXCEPT:

A. Muscles of the tongue develop from the 3rd branchial arch*

B. Beginning at the 7th week of development, the tongue withdraws to a lower position to facilitate proper formation of the secondary palate

C. The thyroid gland develops initially at the foramen cecum area of the tobgue

D. Tuberculum impar and lateral lingual swellings are involved in its development

E. The pharyngeal part of the tongue develops from the hypobranchial eminence
9. Which statement best describes the development of the neural tube?

A. it develops directly from the primitive streak.

B. it develops directly from the notochord.

C. it develops from the ectoderm immediately dorsal to the primitive streak.

D. none of the above.*
10. From which of the following is the periodontal ligament derived:

  1. Dental follicle*

  2. Enamel organ

  3. Dental papilla

  4. Epithelial root sheath

  5. Outer enamel epithelium

11. The chorionic membrane consists of:

A. epiblast, cytotrophoblast, and syncytiotrophoblast

B. hypoblast, cytotrophoblast, and syncytiotrophoblast

C. extraembryonic mesoderm, cytotrophoblast, and syncytiotrophoblast*

D. Heuser’s membrane, extraembryonic mesoderm, and cytotrophoblast

12. Which of the following statements concerning the tympanic cavity is correct?
A. It arises from the otic vesicle
B. It is of endodermal origin*
C. It contains the spiral organ of Corti
D. It contains perilymph
13. What is the usual sequence of events in the histogenesis of a tooth?

(1) Deposition of the first layer of dentin

(2) Deposition of the first layer of enamel

(3) Differentiation of odontoblasts

(4) Elongation of inner dental epithelium
A. (2), (1), (3), (4)

B. (3), (4), (1), (2)

C. (4), (3), (1), (2)*

D. (4), (2), (3), (1)

E. (1), (2), (3), (4)
14. Which of the answers below correctly describe the number of cervical sclerotomes, vertebrae, and spinal nerves, respectively?

A. 8, 8, and 8

B. 8, 7, and 8*

C. 8, 8, and 7

D. 7, 8, and 7
15. The femur bone develops from which of the following?

A. somite mesoderm

B. somatopleuric mesoderm*

C. intermediate mesoderm

D. splanchnopleuric mesoderm
16. The influence of the epithelial and ectomesenchymal elements of the odontogenic apparatus and their products on each other in the formation of the parts of the tooth is described as:

A. Reverse polarization

B. Counter-intuitive process

C. Odontogenic reverse stimulation

D. Reciprocal induction*

E. Indirect induction

17. Each of the following develops as an outpocketing of the gut tube EXCEPT one. Which one is the EXCEPTION?

A. lung

B. liver

C. spleen*

D. pancreas

E. gallbladder

18. Which process establishes the 3 definitive germ layers?

A. Neuralation

B. Gastrulation*

C. Craniocaudal folding

D. Lateral folding
19. Please refer to the sketch below in which is illustrated the head and neck region of a human embryo. The facial process labeled B gives rise to which of the following? For orientation the structure labeled C gives rise to the hyoid bone.

A. Secondary palate and nasal septum

B. Mandible and lower lip*

C. Maxilla and middle portion of the upper lip

D. Secondary palate and lateral portion of upper lip

E. Maxilla and primary palate

20. The ureteric bud gives rise to the

A. genital duct system

B. nephrons

C. nephric vessicle

D. None of the above*
21. The septation of the left and right atrium is completed

A. prior to birth via the cardiac neural crest

B. prior to birth independent of the cardiac neural crest

C. at birth via the cardiac neural crest

D. None of the above*
22. The following statements are true about development of pituitary gland EXCEPT:

A. It is ectodermal in origin

B. Rathke’s pouch (hypophysial diverticulum) is an upgrowth from the roof of the stomatodeum

C. The adenohypophysis and the neurohypophysis portions develop from different sources

D. A downgrowth from the diencephalon contributes to the development of neurohypophysis

E. Rathke’s pouch (hypophysial diverticulum) contributes to the development of neurohypophysis*

23. The ureteric bud and mesonephric duct originate from

A. splanchnopleuric mesoderm

B. somatopleuric mesoderm

C. intermediate mesoderm*

D. A & C
24. Which of the three primary germ layers forms the histologically definitive endocardium of the adult heart?

A. mesoderm*

B. endoderm

C. ectoderm

D. epiblast

E. hypoblast

25. The blood vessels in the 3rd branchial arch become the:

A. Pulmonary circulation

B. Common carotid arteries*

C. Dorsal aorta

D. All of the above

E. None of the above

26. Abnormalities of the inferior parathyroid glands indicate abnormal development of which of the following pharyngeal pouches?

A. 1st

B. 2nd

C. 3rd*

D. 4th
27. Which of the following statements concerning the cochlear duct is correct
A. It arises from pharyngeal arch 4
B. It is of ectodermal origin*
C. It contains the stapes
D. It is an air filled cavity

28. The following statements are true about Meckel’s cartilage EXCEPT:

    1. Completely converts to form the mandible by endochondral ossification*

    2. It is the cartilage of the first branchial arch

    3. The malleus and incus develop from the dorsal aspect of this cartilage

    4. Is innervated by trigeminal nerve

    5. Is in close relationship with the developing mandible but does not contribute to it

29. Pharyngeal cleft 2 gives rise to the

A. Internal auditory meatus
B. External auditory meatus
C. Eustatchian tube
D. Primary tympanic cavity

E. None of the above*

30. The following are true about junctional epithelium EXCEPT:

A. Attached to the tooth surface cervical to the gingival sulcus and continuous with the sulcular epithelium

B. Has a high rate of cell division

C. Readily regenerates from the sulcular epithelium if it is damaged

D. Comprised of orthokeratinized stratified squamous epithelium*

E. Derived from reduced enamel epithelium

31. The surface ectoderm gives rise to the
A. dilator pupillae muscle
B. lens*
C. sclera
D. retina
32. The proepicardium originates within the

A. somatopleuric mesoderm

B. cardiac neural crest

C. Splanchnopleuric mesoderm*

D. None of the above
33. Your first patient presents with a chief complaint of pale yellow spots in the buccal mucosa near the angle of the mouth. You suspect these to be ectopic sebaceous glands. What condition does the patient have?

A. Von Ebners’s disease

B. Fordyce’s disease*

C. Circumvallate papillae

D. Mucous cells

E. None of the above

34. What pharyngeal arch gives rise to muscles that are innervated by the facial cranial nerve (VII)?

A. Pharyngeal arch 1

B. Pharyngeal arch 2*

C. Pharyngeal arch 3

D. Pharyngeal arch 4

E. Pharyngeal arch 6

35. What are the four layers in order from the oral cavity to internal, of the masticatory mucosa?

  1. Stratum corneum, spinosum, basale, and granulosum

  2. Stratum granulosum, spinosum, basale, and corneum

  3. Stratum corneum, granulosum, spinosum, and basale*

  4. Stratum basale, spinosum, granulosum, and corneum

  5. Stratum corneum, granulosum, basale, and spinosum

36. The epithelial rests of Malassez derive from the:

A. Stratum intermedium

B. Dental lamina

C. Stellate reticulum

D. Dental papilla

E. Hertwig’s epithelial root sheath*

37. Name the structures that originates from the 2nd branchial arch

(1) Masseter

(2) Stapes

(3) Buccinator

(4) Inferior alveolar nerve
A. (1) and (4)

B. (1) and (3)

C. (2) and (3)*

D. (2) and (1)

E. (2) and (4)
38. Which of the following is true about fungiform papilla?

A. They constitute majority of the papillae

B. They are the only papillae that does not contain any taste buds

C. Constitute about 10 to 14 in number and present distributed in “V”-shaped pattern between the base and the body of the tongue

D. Contains taste buds and present interspersed between the filiform papillae and usually appears red round structures due to increased blood supply*

E. Present on the lateral margins of the posterior tongue as parallel ridges

39. Which of the following structures are formed from the posterior portion of the Meckel’s cartilage:

A. Stapes

B. Malleus*

C. Mandible

D. Temperomandibular joint

E. The entire cartilage disappears and no structures are formed from the posterior portion








40. Is derived from ectomesenchyme:

A. F

B. G

C. H

D. J

E. K*

41. Forms the cell rests of Serre:

    1. F*

    2. H

    3. I

    4. J

    5. K

42. Will form enamel:

  1. G

  2. H

  3. I

  4. J*

  5. K

43. The cells belonging to which of the above structure form dentin:

A. G

B. H

C. I

D. J

E. K*
44. Name the structure labeled G:

  1. Lateral lamina*

  2. Dental lamina

  3. Vestibular lamina

  4. Enamel knot

  5. Lamina propria

45. Name the structure labeled H:

A. Inner dental epithelium

B. Stellate reticulum*

C. Outer dental epithelium

D. Stratum intermedium

E. Dental papilla
46. Participates in the formation of reduced enamel epithelium:

  1. F and G

  2. G and I

  3. H and G

  4. I and H

  5. I and J*

47. As demonstrated by the pattern of MOTOR innervation, which one of the following is involved in development of the tongue?

A. First branchial arch only

B. First and third branchial arch

C. Occipital somites*

D. Second branchial arch only

E. Third branchial arch only

48. Alteration of the vasculature in the lamina propria and submucosa will most likely result in a clinically apparent alteration in the oral mucosa’s:

A. Texture

B. Surface

C. Integrity

D. Color*

E. None of the above
49. The _________________ surface of the tongue is covered with specialized mucosa, and the ventral surface of the tongue is covered with _____________ mucosa:

A. Ventral, masticatory

B. Dorsal, lining*

C. Dorsal, masticatory

D. Ventral, lining

E. Ventral, specialized

50. Which of the following areas of the oral mucosa has keratinized epithelium:

        1. Gingiva

(2) Buccal mucosa

(3) Ventral tongue

(4) Hard Palate

  1. (1) and (3)

  2. (1) and (4)*

  3. (2) and (3)

  4. (2) and (4)

  5. (3) and (4)



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