Mennerick- ligand Binding Handout



Download 90.5 Kb.
Page7/10
Date24.07.2018
Size90.5 Kb.
1   2   3   4   5   6   7   8   9   10

(4)
so (5)
At this point you’ve just derived the Michaelis-Menten equation, the Langmuir isotherm, and the equation of A.J. Clark applying the law of mass action to receptors (all formally equivalent equations).

Getting back to the significance of the dissociation constant KD, consider the condition



where half the receptors are bound:

or

Substituting from equation 5,




Share with your friends:
1   2   3   4   5   6   7   8   9   10


The database is protected by copyright ©dentisty.org 2019
send message

    Main page