Mcqs Pathology frcs with regard to giant cells

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MCQs Pathology FRCS
1. With regard to giant cells: 

a. they are the hallmark of granulomatous lesion

b. they are derived from macrophages

c. foreign body giant cells occur in chalazion

d. Langhan's giant cells occur in sarcoidosis

e. Langhan's giant cells occur in tuberculosis


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2. The following are of prognostic importance in choroidal melanoma: 

a. presence of retinal detachment

b. size of the tumour

c. location of the tumour

d. presence of blood vessels within the tumour

e. types of tumour cells

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3. In pthisis bulbi: 

a. the intraocular pressure is reduced

b. calcification of the lens is common

c. the sclera is thickened

d. the size of the globe is reduced

e. the retinal pigment epithelium undergoes osseous metaplasia

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4. Common features of retinoblastoma include: 

a. high mitotic figures

b. calfication

c. necrosis

d. presence of extracellular DNA 

e. neovascularization

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5. Optic glioma:

a. has a peak incidence in the middle age

b. is associated with type I neurofibromatosis

c. arises from the oligodendrocytes

d. causes meningeal hyperplasia

e. contains Rosenthal fibres which are essential for its 


1. Sebaceous carcinoma: 

a. is commoner in the upper lid than the lower lid 

b. is usually bilateral 

c. has a yellowish appearance 

d. of the conjunctiva only occurs as a result of pagetoid 
    spread from the eyelid 

e. metastasis usually haematogenous 

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2. The following are features of Muir-Torre's syndrome: 

a. multiple basal cell carcinoma 

b. multiple keratoacanthoma 

c. multiple sebaceous carcinoma 

d. meningioma 

e. adenocarcinoma of the proximal bowel 

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3. Medulloepithelioma: 

a. arises from the non-pigmeneted retinal pigment epithelium 

b. most commonly found on the posterior surface of the iris 

c. is a benign tumour 

d. causes neovascular glaucoma 

e. may contain striated muscle histologically 

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4. In sympathetic ophthalmia: 

a. there are bilateral granulomatous panuveitis 

b. the choriocapillaris are occluded by macrophages 

c. Dalen-Fuch's nodules are found on the inner surface of the 

    Bruch's membrane 

d. Dalen-Fuch's nodules are pathognomonic of this condition 

e. removal of the damaged eye reduces the inflammation 

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5. Rhabdomyosarcoma of the orbit: 

a. typically affects patients in the second decade of life 

b. causes systemic fever 

c. has better prognosis than extraorbital type 

d. of the alveolar type is the most common 

e. is resistant to radiotherapy 

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Test 2

1. Typical  peripheral cystoid degeneration of the retina: 

a. is associated with high myopia

b. produces cystic spaces in the nerve fibre layer

c. increases the risk of retinal detachment

d. has overlying liquefied vitreous 

e. gives rise to retinoschisis through coalescence of the cystic 


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2. The following stains are useful in showing up calcium in the tissue: 

a. Prussian blue 

b. von Kossa

c. Alizarin red

d. crystal violet

e. sudan black

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3. Touton's giant cells occur in: 

a. histiocystosis X 

b. tuberous xanthoma

c. juvenile xanthogranuloma 

d. Erdheim-Chester's disease

e. liposarcoma

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4. Sturge-Weber's syndrome is associated with: 

a. localized form of choroidal haemangioma 

b. meningeal haemangioma

c. neovascular glaucoma

d. optic glioma 

e. cavernous haemangioma

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5. The following are true about orbital meningioma:

a. it is commoner in female than male

b. it usually arises from intracranial extension.

c. it is associated with type I neurofibromatosis

d. orbital calcification is a common feature 

e. Psamomma bodies are essential for histological diagnosis


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