Homo sapiens from Europe supports a Palaeolithic back-migration to Africa’



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Supplementary Table S1. All sites differing between the PM1 mitogenome and the rCRS13. Only reads with a minimum mapping quality of 30 and alleles with a base quality of 30 or more were considered. The column PM1 does not show the consensus allele, it shows any alternative allele found among all reads covering that site. The private mutations of rCRS at positions 4769 and 8860 lacked enough coverage, based on our quality criteria, in the PM1 mitogenome.

SNP pos

rCRS

Alternative allele found in PM1 reads

Number of reads supporting the alternative allele

Total number of reads covering the site

%

73

A

G

28

28

100

263

A

G

66

66

100,0

310

T

insC

4

9

44,4

679

C

T*

2

12

16,7

750

A

G

32

34

94,1

1239

C

T*

3

19

15,8

1438

A

G

13

13

100,0

2496

G

A*

2

7

28,6

2706

A

G

50

53

94,3

3105

A

delC

1

37

2,7

3348

A

G

48

48

100,0

3566

C

T*

4

33

12,1

4850

C

T*

2

10

20,0

5294

C

T*

2

7

28,6

5300

C

T*

2

9

22,2

5312

C

T*

2

11

18,2

5871

G

A*

2

12

16,7

5881

G

A*

2

7

28,6

6651

G

A*

2

13

15,4

7028

C

T

4

4

100,0

7252

G

A*

4

31

12,9

7648

C

T*

2

11

18,2

8083

C

T*

2

13

15,4

8609

C

T*

2

6

33,3

9209

G

A*

2

5

40,0

9470

C

T*

2

7

28,6

10517

T

A

15

16

93,8

11467

A

G

39

40

97,5

11719

G

A

11

11

100,0

12308

A

G

45

45

100,0

12372

G

A

27

27

100,0

12838

G

A*

5

41

12,2

14766

C

T

30

31

96,8

15326

A

G

57

60

95,0

16172

T

C

27

30

90,0

* Sites where potential post-mortem damage could explain the non-consensus reads.

Supplementary Table S2. Mitogenomes used in phylogenetic analysis (Fig. 1A)

Sample

Taxonomy

Age (ky BP)

Genbank ref.

Reference

Dolni Vestonice 14

Modern human

31

KC521458

18

Kostenki 14

Modern human

38

FN600416

23

Ust-Ishim

Modern human

45

PPRJEB6622

24

Fumane 2

Modern human

40




25

Tianyuan

Modern human

39

KC417443

23

El Sidron 1253

Neanderthal

39

FM865409

26

Mezmaiskaya 1

Neanderthal

65

FM865411

26

Denisova 1

Denisovan

41

FN673705

27

Denisova 2

Denisovan

41

FR695060

28

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