In 1965, 17-year-old high school student, Randy Gardner stayed awake for 264 hours. That's 11 days to see how he'd cope without sleep. On the second day, his eyes stopped [to focus/focusing]. Next, he lost the ability to identify objects by touch. By day three, Gardner was moody and uncoordinated. At the end of the experiment, he was struggling to concentrate, had trouble with short-term memory, became paranoid, and started hallucinating. Although Gardner recovered without long-term psychological or physical damage, for others, losing shuteye can result in hormonal imbalance, illness, and, in extreme cases, death.
Q1. 11일동안 잠을 자지 않았을 때Randy Gardner에게는 어떤 증상이 나타났나? We're only beginning to understand why we sleep to begin with, but we do know it's essential. Adults need seven to eight hours of sleep a night, and adolescents need about ten. We grow sleepy due to signals from our body [tells/telling] our brain we are tired, and signals from the environment telling us it's dark outside. The rise in sleep-inducing chemicals, like adenosine and melatonin, sends us into a light doze that grows deeper, making our breathing and heart rate slow down and our muscles [to relax/relax]. This non-REM sleep is when DNA is repaired and our bodies replenish themselves for the day ahead.
Q2. Adenosine과 melatonin은 어떤 기능을 하는가? In the United States, it's estimated that 30% of adults and 66% of adolescents are regularly sleep-deprived. This isn't just a minor inconvenience. Staying awake can cause serious bodily harm. When we lose sleep, learning, memory, mood, and reaction time are affected. Sleeplessness may also cause inflammation, halluciations, high blood pressure, and it's even been linked to diabetes and obesity. In 2014, a devoted soccer fan [died/has died] after staying awake for 48 hours to watch the World Cup. While his untimely death was due to a stroke, studies show that chronically sleeping fewer than six hours a night [increase/increases] stroke risk by four and half times compared to [them/those] getting a consistent seven to eight hours of shuteye.
Q3. 지속적으로 6시간 이하로 잠을 잤을 때 뇌졸중에 걸릴 확률은 어떻게 변하는가? For a handful of people on the planet [which/who] carry a rare inherited genetic mutation, sleeplessness is a daily reality. This condition, known as Fatal Familial Insomnia, places the body in a nightmarish state of wakefulness, forbidding it from entering the sanctuary of sleep. Within months or years, this progressively worsening condition leads to dementia and death.
How can sleep deprivation cause such immense suffering? Scientists think the answer lies with the accumulation of waste products in the brain. During our waking hours, our cells are busy using up our day's energy sources, which [is/get] broken down into various byproducts, including adenosine. As adenosine builds up, it increases the urge to sleep, also known as sleep pressure. In fact, caffeine works by blocking adenosine's receptor pathways. Other waste products also build up in the brain, and if they're not cleared away, they collectively overload the brain and lead to the many negative symptoms of sleep deprivation.
Q4. 카페인은 뇌에서 어떤 역할을 하나? So, what's happening in our brain when we sleep to prevent this? Scientists found something called the glymphatic system, a clean-up mechanism that removes this buildup and is much more active when we're asleep. It works by using cerebrospinal fluid to flush away toxic byproducts that accumulate between cells. Lymphatic vessels, which serve as pathways for immune cells, have recently [discovered/been discovered] in the brain, and they may also play a role in clearing out the brain's daily waste products.
Q5. Glymphatic system이 하는 일은 무엇인가? While scientists continue exploring the restorative mechanisms behind sleep, we can be sure that slipping into slumber is a necessity if we want to maintain our health and our sanity.