What I have to say is an essence of views distilled out of forty years of grappling with the fundamental problems of obesity, its causes, its symptoms, and its very nature



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HYPOPHYSIS . . . Another name for the pituitary gland.

HYPOTHESIS . . . A tentative explanation or speculation on how observed facts and isolated scientific data can be brought into an intellectually satisfying relationship of cause and effect. Hypotheses are useful for directing further research, but they are not necessarily an exposition of what is believed to be the truth. Before a hypothesis can advance to the dignity of a theory or a law, it must be confirmed by all future research. As soon as research turns up data which no longer fit the hypothesis, it is immediately abandoned for a better one.

LSH . . . See corpus luteum.

METABOLISM . . . See basal metabolism.

MIGRAINE . . . Severe half-sided headache often associated with vomiting.

MUCOID . . . Slime-like.

MYOCARDIUM . . . The heart-muscle.

MYOMA . . . See fibroid.

MYXEDEMA . . . Accumulation of a mucoid substance in the tissues which occurs in cases of severe primary thyroid deficiency.

 

NEOLITHIC . . . In the history of human culture we distinguish the Early Stone Age or Paleolithic, the Middle Stone Age or Mesolithic and the New Stone Age or Neolithic period. The Neolithic period started about 8000 years ago when the first attempts at agriculture, pottery and animal domestication made at the end of the Mesolithic period suddenly began to develop rapidly along the road that led to modern civilization.



NORMAL SALINE . . . A low concentration of salt in water equal to the salinity of body fluids.

PHLEBITIS . . . An inflammation of the veins. When a blood-clot forms at the site of the inflammation, we speak of thrombophlebitis.

PITUITARY . . . A very complex endocrine gland which lies at the base of the skull, consisting chiefly of an anterior and a posterior lobe. The pituitary is controlled by the diencephalon, which regulates the anterior lobe by means of hormones which reach it through small blood vessels. The posterior lobe is controlled by nerves which run from the diencephalon into this part of the gland. The anterior lobe secretes many hormones, among which are those that regulate other glands such as the thyroid, the adrenals and the sex glands.

PLACENTA . . . The after-birth. In women, a large and highly complex organ through which the child in the womb receives its nourishment from the mother's body. It is the organ in which HCG is manufactured and then given off into the mother's blood.

PROTEIN . . . The living substance in plant and animal cells. Herbivorous animals can thrive on plant protein alone, but

 

man must have some protein of animal origin (milk, eggs or flesh) to live healthily. When insufficient protein is eaten, the body retains water.



PSORIASIS . . . A skin disease which produces scaly patches. These tend to disappear during pregnancy and during the treatment of obesity by the HCG method.

RENAL . . . Of the kidney.

RESERPINE . . . An Indian drug extensively used in the treatment of high blood pressure and some forms of mental disorder.

RETENTION ENEMA . . . The slow infusion of a liquid into the rectum, from where it is absorbed and not evacuated.

SACRUM . . . A fusion of the lower vertebrate into the large bony mass to which the pelvis is attached.

SEDIMENTATION RATE . . . The speed at which a suspension of red blood cells settles out. A rapid settling out is called a high sedimentation rate and may be indicative of a large number of bodily disorders of pregnancy.

SEXUAL SELECTION . . . A sexual preference for individuals which show certain traits. If this preference or selection goes on generation after generation, more and more individuals showing the trait will appear among the general population. The natural environment has little or nothing to do with this process. Sexual selection therefore differs from natural selection, to which modern man is no longer subject because he changes his environment rather than let the environment change him.

STRIATION . . . Tearing of the lower layers of the skin owing to rapid stretching in obesity or during pregnancy. When first formed striae are dark reddish lines which later change into white scars.

SUPRARENAL GLANDS . . . See adrenals.

SYNDROME . . . A group of symptoms which in their association are characteristic of a particular disorder.

THROMBOPHLEBITIS . . . See phlebitis.

THROMBUS . . . A blood-clot in a blood-vessel.

TRIAMCINOLONE . . . A modern derivative of cortisone.

URIC ACID . . . A product of incomplete protein-breakdown or utilization in the body. When uric acid becomes deposited in the gristle of the joints we speak of gout.

VARICOSE ULCERS . . . Chronic ulceration above the ankles due to varicose veins which interfere with the normal blood circulation in the affected areas.

VEGETATIVE . . . See autonomous.

VERTEBRATE . . . Any animal that has a back-bone.

 

Literary References to the Use of



Chorionic Gonadotrophin

In Obesity

 

 



THE LANCET

Nov. 6, 1954             Article                                     Simeons

Nov. 15, 1958            Letter to Editor                         Simeons

July 29, 1961             Letter to Editor                         Lebon

Dec. 9, 1961              Article                                    Carne

Dec. 9, 1961              Letter to Editor                         Kalina

Jan. 6, 1962               Letter to Editor                        Simeons

Nov. 26, 1966             Letter to Editor                        Lebon

 

THE JOURNAL OF THE AMERICAN GERIATRIC SOCIETY

Jan. 1956 Article                                     Simeons

Oct. 1964                Article                                     Harris& Warsaw

Feb. 1966                Article                                     Lebon

 

THE AMERICAN JOURNAL OF CLINICAL NUTRITION

Sept.-Oct. 1959       Article                                     Sohar

March 1963             Article                                     Craig et al.

Sept. 1963               Letter to Editor                        Simeons

March 1964             Article                                     Frank

Sept. 1964               Letter to Editor                        Simeons

Feb. 1965                Letter to Editor                        Hutton

June 1969                Editorial                                  Albrink

June 1969                Special Article                         Gusman

 

THE JOURNAL OF PLASTIC SURGERY (British)

April 1962               Article                                     Lebon

 

THE SOUTH AFRICAN MEDICAL JOURNAL

Feb 1963 Article                                     Politzer, Berson & Flaks

 

 



A.T.W. SIMEONS

POUNDS AND INCHES Privately printed: obtainable only from A.T.W. Simeons, Salvator Mundi International Hospital, Rome, Italy

VETSUCHT (Netherlands Edition) Wetenschappelijke Uitgeverij, N.V. Amsterdam

MAN’S PRESUMPTUOUS BRAIN Longman’s, Green, London

E.P. Dutton, New York (hardback)

Dutton Paperbacks, New York


 
[1] A list of references to the more important articles is given at the end of this booklet.

[2] “Current account” is the British name for what Americans call a checking account.

[3] There is some clinical evidence to suggest that those symptoms of Cushing’s Syndrome which resemble true obesity are caused by the same mechanism which causes common obesity, while the other symptoms of  the syndrome are directly due to adrenocortical dysfunction.

[4] World War II.

[5] Confinement = the concluding state of pregnancy

[6] As we are speaking of purely regulatory disorders, we obviously exclude all such cases in which there are gross organic lesions of the pituitary or of the sex-glands themselves.

[7] We use 1 tablet of hygroton.

[8] NOTE: This practice is obsolete.  Modern sanitary methods dictate throwing away used needles and syringes and using new ones for each injection.

[9] Wherever unfamiliar terms are used, they will be found in their respective alphabetical place.  The lay reader can therefore make his own cross-reference.

 

 


 

 


 

 









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