Testimony of Dr. Hal Huggins before the FDA Advisory Panel on Mercury Dental Fillings
All right. This is an explanation basically of the graph that I like to use in determining the changes that have occurred in we have got about 200,000 chemistries over a period of 38 years. Most of the changes that are shown here occurred within six to ten days. What we are trying to do is show that there's a stability point.
Normal range as shown on the bottom of this covers by definition 95.56 percent of the population, but over a period of time the high has come down. The lows come up upon dental intervention, and there appears a stability point.
The stability point is an area which doesn't move a whole lot, and it is the area in which you find most people who do not have disease.
Ten years ago, the Adolph Coors Foundation sponsored a study on 30 patients with at least three amalgams and no more than 11. These people had no other dental restorative materials in their mouths, no nutrition or any other intervention was performed. Chemistries were run, amalgams removed, composites placed; duplicate chemistries were placed. A lot of changes were noted.
The most unexpected change was in cholesterol. Here you can see that the higher cholesterol levels dropped, some over 40 to 50 milligrams percent.
Expanding this into the non-Coors study, we found in a study with people with excess of 250 milligrams that the drops were 80 to 100 milligrams percent in six days after amalgam removal without any drug intervention.
Hemoglobin has four binding sites into which oxygen can attach. Mercury has a high affinity for these sites. Should two sites be saturated with mercury the total carrying capacity for oxygen drops 50 percent.
As curious as that, the sequential removal of amalgam frequently produced a drop in the red cell count, hemoglobin, and hematocrit. This was accompanied by a simultaneous increase in urinary excretion of mercury. We expected red cell values to be reflected in an increase in fatigue. However, the patients reported a dramatic increase in energy. Now, where did this come from?
A study of the venous oxyhemoglobin or the actual oxygen carrying saturation showed the answer where huffing and puffing might increase oxyhemoglobin one percent. Dental intervention produced an average increase in oxygen of 22.5 percent with some values reaching as much as 40 percent increase in oxygen.
Where does hemoglobin come from? From porphyrins in the blood stream. Porphyrins develop into heme, from there into hemoglobin, and by another pathway into ATP. If there is a toxic blockage somewhere, porphyrins are excreted in the urine.
The presence of toxicity is sometimes assessed by measuring the amount of porphyrins in the urine. This is a slide of a male that has never had amalgam in his mouth. The test shows only one porphyrin, the four carboxy, and the total was 12 micrograms.
This porphyrin test is on a wheelchair bound multiple sclerosis patient showing the presence of four, five, six, seven and eight carboxy porphyrins with a total of 2,400 micrograms in the urine. Ten days after dental intervention -- that means getting rid of the amalgam and other things -- the level had dropped to 200 micrograms. This means that far more energy was available for normal biochemical reactions and less energy was literally going down the toilet.
Is there any wonder that the patient was able to get out of the wheelchair and take a few steps unaided?
Looking further into multiple sclerosis, these spinal tap results show multiple unusual proteins in the spinal fluid. Albumen which is present at about 55 kilodaltons is the only protein that should be there.
The next slide looks very similar because on the right side of the test, the same patient, you find only albumen. Four days after dental intervention all four patients physically improved and all four demonstrated a total disappearance of the unusual proteins. Only albumen remained. Were these the illegal clonal globulins that disappeared?
Is there a mechanism that could link mercury to an autoimmune response similar to that in MS? The meter histocompatibility complex, MHC, on the cell's surface signals to the immune system whether a cell is self or non-self. Non-self or abnormal cells are flagged for destruction. Should an atom of mercury bind to a sulfur binding site on the cell surface, the MHC is altered such that the normal self cell will be seen as non-self or abnormal and be scheduled for destruction. Thus the origin of autoimmune disease.
Now, I'll cut this one briefly. Those of you who have experience in immunology would recognize lymphocyte viability, and you notice after four days' exposure to the amount of mercury that you would have in six fillings. The lymphocyte viability dropped from 100 percent, to 92 percent, to 21 percent. This suggests that the differential slide of the CBC is not always indicative of immune competence.
This slide demonstrates normal DNA, contains a single spike of chromosome numbers and more than one by definition is malignant. This patient showed abnormal physiological changes immediately after the placement of dental materials. Serious immune deficit was found, but surprisingly a malignant DNA was also found.
Within two months after dental intervention, the malignancy was changed to nonmalignant. The conclusion is objective laboratory evidence confirms that adverse effects of mercury on biochemistry are amenable to dental interventions. Clear our DNA. Ban amalgam.
Thank you, ladies and gentlemen.