Supplementary Table S1: Training and Test Cohorts of Burkitt Lymphoma



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Supplementary Table S1: Training and Test Cohorts of Burkitt Lymphoma.





Case

Figure Code

Subtype

Age of patient (years)

Sex

Site of Biopsy

Age of Biopsy (years)

Diagnostic Score

MYC Activity Score

MYC IHC (%)

MYC Rearrangement*

Training Cohort




1

BL1

Endemic

3

M

Submandibular mass

6

0.999

0.945

80

NA




2

BL2

Sporadic

25

F

Right Adnexal Mass

12

0.996

1

60

1




3

BL3

Sporadic

8

M

Neck mass

6

0.996

0.998

-

NA




4

BL4

Endemic

9

M

Tibial Mass

6

0.996

0.994

60

NA




5

BL5

Sporadic

32

F

Epidural Mass

9

0.893

0.982

70

1




6

BL6

Sporadic

29

M

Lymph Node

9

0.85

0.996

80

1




7

BL7

Sporadic

21

M

Mediastinal Mass

5

0.845

0.997

100

1




8

BL8

Immunodeficiency

62

M

Parotid mass

4

0.841

0.994

100

1




9

BL9

Immunodeficiency

41

M

Lymph Node

9

0.829

1

100

1




10

BL10

Sporadic

32

F

Lymph Node

9

0.632

0.629

80

1




11

BL11

Immunodeficiency

47

M

Lymph Node

6

0.551

0.999

100

1




12

BL12

Sporadic

41

F

Retroperitoneal Mass

6

0.306

0.952

70

1

Test Cohort




1

tBL1

Sporadic

4

M

Pelvic soft tissue mass

3

0.946

0.996

80

1




2

tBL2

Sporadic

42

F

Thyroid Mass

10

0.883

0.996

0

1




3

tBL3

Sporadic

40

F

Ovary and fallopian tube

0.5

0.877

0.955

0

1




4

tBL4

Sporadic

55

M

Right Mandibular mass

11

0.845

0.862

90

1




5

tBL5

Immunodeficiency

41

M

Lymph node

7

0.811

0.919

60

1




6

tBL6

Sporadic

10

M

Nasopharyngeal mass

10

0.802

0.963

90

1




7

tBL7

Sporadic

47

M

Mediastinal Mass

10

0.766

0.969

10

1




8


tBL8

Sporadic

33

M

Right Neck mass

7

0.682

0.991

80

NA




9

tBL9

Sporadic

44

M

Lymph node

9

0.641

0.975

90

1




Failed QC

tBL10

Sporadic

27

M

Oropharynx

1

-

-

100

1




Failed QC

tBL11

Sporadic

14

F

Pelvic mass

1

-

-

100

1




Failed QC

tBL12

Sporadic

45

M

Right Femur

2

-

-

90

1

Tumors with no recorded values for the diagnostic and MYC activity classifiers had failed analytical quality control and were therefore excluded from the training and test sets.



*For all references to MYC-, BCL2-, and BCL6- rearrangement, “1” denotes confirmed rearrangement, “0” rearrangement not tested.

F, female; M, male; NA, not available.


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