Supplementary Table demographic characteristics



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Supplementary Table S1. Demographic characteristics

Case number

Gender

Age

Diagnosis

Duration from diagnosis to cell therapy, months

Prior surgery

Prior chemotherapy

Prior radiation therapy

Primary metastatic disease

Recurrent disease

C1-01

M

64

Diffuse large B cell lymphoma

81

no

yes

yes

NA

yes

C1-02

M

60

Renal cell carcinoma

207

yes

yes

no

yes

no

C1-03

M

62

Thymic carcinoma

55

no

yes

yes

yes

no

C2-01

F

62

Ovarian cancer

26

no

yes

no

yes

no

C2-02

M

61

Maxillary cancer

137

yes

yes

yes

yes

yes

C2-03

M

51

Rectosigmoid colon cancer

51

yes

yes

yes

no

yes

C3-01

F

69

Adenoid cystic carcinoma

93

yes

yes

yes

no

yes

C3-02

M

63

Transitional cell carcinoma

44

yes

yes

no

no

yes

C3-03

M

54

Tongue cancer

26

yes

yes

yes

no

yes

C4-01

M

50

Extranodal NK/T-cell lymphoma, nasal type

9

no

yes

no

NA

yes

C4-02

M

54

Nasopharyngeal cancer

55

no

yes

yes

yes

no

C4-03

M

62

Non-small cell lung cancer

15

no

yes

no

yes

no

C5-01

M

66

Renal cell carcinoma

41

yes

yes

no

no

yes

C5-02

M

68

Adenoid cystic carcinoma

54

yes

yes

no

no

yes

C5-03

M

74

Esophageal cancer, Stomach cancera

12

no

yes

yes

yes

no

C5-04

F

50

Ovarian cancer

139

yes

yes

no

no

yes

C6-01

M

78

Non-small cell lung cancer

35

yes

yes

no

no

yes

C6-02

F

48

Adenoid cystic carcinoma

7

yes

yes

yes

no

yes

C6-03

M

64

Papillary thyroid carcinoma

31

yes

no

yes

no

yes

C6-04

M

55

Non-small cell lung cancer

12

no

yes

yes

yes

no

Abbreviation: NA, not assessable.

aDouble primary cancer.

Supplementary Table S2. Post-transfusion kinetics of donor NK cells in recipient peripheral blood

Recipient

Persistence of donor NK cells by nested PCR

1st injection

2nd injection

3rd injection

C1-01

1 day





C1-02

1 day





C1-03

ND





C2-01

4 days





C2-02

1 hour





C2-03

1 hour





C5-01

3 days

2 days

1 day

C5-03

2 hours

2 hours

2 hours

C5-04

2 days

1 day

4 hours

C6-02

3 days

1 day

4 hours

C6-03

NA

NA

NA

C6-04

3 days

2 hours

2 hours

Abbreviations: ND, not detected; NA, not applicable for this assay due to the same HLA-DRB1 allele between donor and recipient.


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