Supplementary Table 2



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Supplementary Table 2. Genes that significantly change expression upon KAT6B depletion. Normalized intensities from the array in each sample and log Fold Changes from the analysis are depicted.
List of 32 commonly downregulated genes upon depletion of KAT6B gene in NCI-N417 and HCC-33 cell lines.

logFC_HCC33

logFC_N417

GeneSymbol

GeneName

N417_sh5

N417_sh8

HCC33_sh5

HCC33_sh8

N417_scr5

N417_scr8

HCC33_scr5

HCC33_scr8

-1.382

-0.753

TRPM8

transient receptor potential cation channel, subfamily M, member 8

5.085

4.858

6.224

5.758

5.626

5.306

7.217

7.064

-1.237

-0.772

TPTE2

transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

4.849

4.731

4.778

4.898

5.353

5.127

5.925

5.224

-1.124

-0.623

KAT6B

K(lysine) acetyltransferase 6B

6.858

7.158

7.418

7.875

7.547

7.546

8.705

8.713

-1.026

-1.188

ICK

intestinal cell (MAK-like) kinase

7.772

7.546

7.134

6.758

8.713

8.807

7.831

7.925

-0.943

-1.313

PAN3-AS1

PAN3 antisense RNA 1 (non-protein coding)

6.073

6.044

5.882

5.954

7.277

7.021

6.461

6.901

-0.933

-0.738

ALB

albumin

4.622

4.662

5.028

5.042

5.077

4.951

5.953

5.306

-0.922

-0.769

JAM3

junctional adhesion molecule 3

9.370

8.874

9.333

9.220

9.946

9.798

10.113

10.252

-0.882

-0.876

OR2T6

olfactory receptor, family 2, subfamily T, member 6

5.212

4.731

5.028

5.116

5.464

5.596

5.560

5.690

-0.850

-0.981

NEAT1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

11.462

10.973

5.917

6.299

11.936

12.411

6.582

7.039

-0.811

-0.717

PPAPDC3

phosphatidic acid phosphatase type 2 domain containing 3

9.475

9.414

5.772

5.838

10.405

9.867

6.202

6.684

-0.779

-0.612

CDKL4

cyclin-dependent kinase-like 4

5.031

5.152

4.778

4.855

5.482

5.539

5.212

5.253

-0.754

-0.794

CNIH3

cornichon homolog 3 (Drosophila)

6.695

6.746

5.373

5.069

7.607

7.204

5.778

5.644

-0.743

-0.836

CPS1

carbamoyl-phosphate synthase 1, mitochondrial

4.687

4.637

5.111

5.183

4.943

5.267

5.533

5.709

-0.741

-0.716

BNIP3L

BCL2/adenovirus E1B 19kDa interacting protein 3-like

9.753

9.705

9.633

9.659

10.314

10.506

10.321

10.430

-0.722

-0.944

LAMA4

laminin, alpha 4

5.358

5.833

4.858

5.183

6.375

6.294

5.494

5.392

-0.709

-0.659

CCL28

chemokine (C-C motif) ligand 28

4.367

4.422

4.604

4.855

4.562

4.690

5.055

5.088

-0.696

-1.480

FAM3C

family with sequence similarity 3, member C

8.583

7.615

7.790

7.375

9.252

9.762

8.194

8.272

-0.650

-0.734

CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

4.622

4.701

4.543

4.690

5.155

4.925

4.855

4.948

-0.643

-1.539

ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

6.498

5.799

4.925

5.116

7.010

7.875

5.302

5.498

-0.601

-1.435

CMA1

chymase 1, mast cell

4.604

4.243

4.460

4.422

4.778

5.306

4.637

4.673

-0.580

-0.746

ITPRIP

inositol 1,4,5-trisphosphate receptor interacting protein

8.775

8.716

9.365

8.982

9.702

9.241

9.799

9.683

-0.576

-1.602

MIAT

myocardial infarction associated transcript (non-protein coding)

6.054

5.409

11.643

11.635

6.820

7.047

12.232

12.182

-0.554

-0.610

ADAMTS15

ADAM metallopeptidase with thrombospondin type 1 motif, 15

4.711

4.731

4.874

4.742

5.055

5.031

5.180

5.003

-0.536

-0.867

GNAS-AS1

GNAS antisense RNA 1 (non-protein coding)

9.515

9.118

7.539

7.700

10.357

9.960

8.060

8.182

-0.535

-0.631

DTX2

deltex homolog 2 (Drosophila)

4.983

4.858

5.085

5.082

5.274

5.364

5.390

5.422

-0.534

-0.884

MRPS10

mitochondrial ribosomal protein S10

11.020

10.480

10.780

10.743

11.652

11.541

11.450

11.133

-0.517

-0.676

JHDM1D

jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)

6.997

6.838

6.045

6.017

7.607

7.396

6.451

6.439

-0.514

-0.640

YRDC

yrdC domain containing (E. coli)

12.330

12.105

12.198

12.459

12.768

12.952

12.898

12.784

-0.490

-0.610

SLC38A10

solute carrier family 38, member 10

5.142

5.152

5.692

5.570

5.464

5.692

6.054

5.925

-0.487

-0.961

PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

8.325

8.185

5.085

5.152

8.992

9.343

5.422

5.407

-0.453

-0.857

SEC61A2

Sec61 alpha 2 subunit (S. cerevisiae)

6.553

6.484

6.274

6.179

7.489

6.998

6.640

6.558

-0.450

-0.611

ARL8A

ADP-ribosylation factor-like 8A

11.492

11.279

11.538

11.554

12.028

11.926

11.942

12.045



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