Supplementary material: Linking Signaling Pathways to Transcriptional Programs in Breast Cancer



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Supplementary material: Linking Signaling Pathways to Transcriptional Programs in Breast Cancer

Hatice U. Osmanbeyoglu, Raphael Pelossof, Jacqueline F. Bromberg, Christina S. Leslie



Table of Contents

  1. Supplemental Figures

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  1. Supplemental Tables

Table S1………………………………………………………………………….21

Table S2………………………………………………………………………….22

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Table S7………………………………………………………………………….27

  1. Supplementary Materials………...………………………………..Separate File

  2. Supplemental Methods…………………………………………………………29

  3. Supplementary References……………………………………………………..36



Supplementary Figures




Figure S1. Performance of the trained affinity regression model on an independent test set of TCGA samples, compared to nearest neighbor. Plot showing Spearman correlations between predicted and actual gene expression changes relative to a median reference using the affinity regression model (y-axis) and nearest neighbor (x-axis) for TCGA test samples representing four breast cancer subtypes (Basal-like, LumA, LumB).


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