Report from the Investigation Commission appointed by Rikshospitalet – Radiumhospitalet mc and the University of Oslo January 18, 2006



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Annex 3: Files and lists which the Commission has used in the investigation of the articles in New England Journal of Medicine 2001 and 2004


File name

Records

Note

Source/year49

Updated rawdata

(Excel)


150 records

First file sent to the US for New England Journal of Medicine 2004

Does not have a link key



JJL 2006

Sudbø8

(Excel)


150 records

Last file sent to the US for New England Journal of Medicine 2004

Does not have a link key



JJL 2006

Reith paper list (rawdata oral mucosa)

150 records

Identical to Sudbø8 on date variables – contains also block numbers on 142 records which enables linkage

AR 2006

L29

(Excel)


147 records

(block numbers)



Contains the same block number as Reith paper list. The heading of the list is “Date: April 15, 1998 Main record Jnr L29 Project Oral Mucosa Paraffin Blocks from Haukeland”

Radiumhospitalet

L31

(Excel)


106 records

(block numbers)



Date: April 1998 Main record Jnr:L31 Project Oral Mucosa Paraffin Blocks from Haukeland. Cut 50umxn. Method: monolayer presentation. Protease 60min, Hydrolysis 60min

Sent from HD 2006

L34

(Excel)


69 records

(block numbers)



Date: March 8, 1999 Main record Jnr:L34 Material: Dysplasia from Fac. of Odontology. Received blocks, cut 50um + 3 uncolored biopsy specimens Method: Monolayer Feulgen colored + color HE of 1 uncolored cut Protease 0.5mg/ml for 60 min 37C. 5N HCI 60min Basic Fuchsin 2 hours

NB! Acc. to agreement with Jon this protocol is excluded. Samples in this series is given L31

October 23, 2001 Tidied in biopsy specimens and blocks. Biopsy specimens not changed to L31. Consequently filed under L34.

Project responsible: Jon Sudbø Sign.:

Date:


Sent from HD 2006

L47

(Excel)


64 records

(block numbers)



Date: March 24, 2000 Main record Jnr:L47 Material: Normal mucosa

Method: monolayer from paraffin-imbedded material

1. One HE cut if little material, only monolayer to be made 2. nx 50 um biopsy specimens 3. One HE2 cut

Project responsible: Jon Sudbø Sign.:

Date:

December 2000. Project completed delivered to Jon



Date: March 24, 2000 Main journal


Sent from RP 2006






Ploidy list

(Excel)


393 lines in the Excel sheet

File name: All Original blocks and HE biopsy specimens linked to ploidy prep and the L29 series.xls

Contains a link between ploidy preparation and block number and link to the L29 series



Produced by RP

2006


Dnr-js2

(Excel)


226 persons – 61

Lacks p.id. no.



File delivered from the Cancer Registry to Sudbø in 1996

The Cancer Registry 1996

X diagnoses

(SPSS)


311 records for

195 persons



All at Dnr-js2 with cancer diagnosis per 2006 (195 of 226 persons)

The Cancer Registry 2006

X persons

(SPSS)


226 persons

All at Dnr-js2 supplemented by p.id.no. and date of death per 2006

The Cancer Registry 2006

Gade

590 records

162 persons



All referring letters from Gade concerning persons from Dnr-js2

The Cancer Registry 2006

The Odontology,

Oslo


132 records

62 persons



All referring letters from the Odontology, Oslo, concerning persons from Dnr-js2

The Cancer Registry 2006

Paper list Gade

178 records

(block number)

144-146 persons


Received de-identified with block number

Gade 1997



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