Remineralisation of primary root caries with amine fluoride New trial: Combined use of a dental rinse containing amine fluoride and toothpaste promotes remineralisation of primary root caries in risk patients



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Press release – Petersson trial elmex® SENSITIVE (specialist press)

Press Release

Remineralisation of primary root caries with amine fluoride
New trial: Combined use of a dental rinse containing amine fluoride and toothpaste promotes remineralisation of primary root caries in risk patients. Noticeable reduction in pain sensitivity.
Place, date – Daily combined use of a dental rinse containing amine fluoride and toothpaste remineralises primary root caries in risk patients. The combined use of these products also promotes inactivation of caries lesions. This was the outcome of a recent trial conducted by Professor Lars Petersson’s working group at the University of Halmstad, Sweden. The scientists investigated the degree of remineralisation of root caries lesions in 70 volunteers over a period of 12 months.
The test persons aged between 55 and 81 years with at least two primary root caries lesions were randomly allocated to two groups each of 35 persons. At the start of the trial, the mineral content of the dentin was measured using an electronical caries monitor (ECM) and the degree of caries damage was classified as hard (non-active), leathery or soft (both active) based on differences in electrical resistance. The subjects in Group 1 brushed their teeth twice daily with elmex Sensitive toothpaste and rinsed twice daily with a dental rinse from the same brand. The subjects in Group 2 used the same toothpaste, but rinsed with a placebo mouth wash solution without fluoride. The electrical resistance of selected lesions was measured at the start of the study and after 3, 6, 9, and 12 months.
After 12 months the number of caries lesions whose status had changed from active to passive was significantly higher in the group who had used the elmex Sensitive toothpaste and dental rinse in combination than in the control group. At the same time, the electrical resistance of selected lesions, which provides information on the mineral content of the hard tooth substance, was statistically higher in this group. Furthermore, pain sensitivity among the subjects from Group 1 had declined by 56% after 12 months, whereas the group that had used a placebo mouth wash solution felt only 20% less pain.
“The results of the trial clearly show that amine fluoride supports the deposition of minerals in the dental hard substance and promotes inactivity of caries”, explains Christiane Spiegelhalder, Head of the Scientific Affairs Department at GABA, specialist in oral care. She attributes the good results of this analysis, above all, to the specific properties of amine fluoride. “Amine fluoride leads to the formation of a protective layer on the dentin containing calcium fluoride, which helps promote remineralisation and seal dentin canals. This reduces pain sensitivity.” On conclusion of the trial, 82% of users from the first test group were satisfied with the elmex Sensitive products.

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Literature:

Petersson LG, Hakestam U, Baigi A, Lynch E. Remineralisation of primary root carious lesions using an amine fluoride rinse. Am J Dent 20 (2007), 93-96.


Press contact:

GABA International AG

Dr. Stefan Hartwig

Emil Frey-Strasse 100

4142 Münchenstein

Switzerland

Phone: +41 61 415 60 74

Fax: +41 61 415 60 00



e-Mail: info@gaba.com


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