Dental Considerations: Local anesthesia with vasoconstrictor ok. Gingivitis, gingival bleeding, headache, fever. Increased alveolitis post tooth extraction.
Dental Drug Interactions: If give oral antibiotic must use different method of birth control until next menses. Barbiturates decrease effect of this medication, increases toxicity of Tylenol,anticoagulants, benzodiazepines, and corticosteroids.
Estrogen and Medroxyprogesterone (Prempro, Premphase)
Ethinyl Estradiol and Norethindrone (Ortho-Novum, Loestrin, Loestrin Fe, Norinyl)
Ethinyl Estradiol and Norgestrel (Lo/Ovral)
Estrogen and Progestin Combination (continued)
Ethinyl Estradiol and Norgestimate (Ortho Tri-Cyclen)
Ethinyl Estradiol and Levonorgestrel (Triphasil, Levlen, Tri-Levlen, Levlite)
Ethinyl Estradiol and Desogestrel (Desogen, Orthocept)
Ethinyl Estradiol and Ethynodiol Diacetate (Demulen)
Estrogen and Androgen Combinations
Action: Estrogen is hormone for growth, development and maintenance of the female reproductive system.
Androgen is hormone which stimulates receptors in organs and tissues to promote growth and development of male sex organs and maintain secondary sex characteristics in androgen deficient males.
Use: Atrophic vaginitis, hypogonadism, primary ovarian failure, vasomotor symptoms of menopause, prostatic carcinoma and prophylaxis for osteoporosis.
Dental Considerations: Local anesthesia with vasoconstrictor ok. Increased alveolitis post tooth extraction. Gingivitis, gingival bleeding, blood dyscrasias and headache.
Dental Drug Interactions: Decreases effect of oral anticoagulants. Increases insulin requirement. Increases action of corticosteroids. Oral antibiotics may decrease estrogen effect.
Estrogen and Methyltestosterone (Estratest)
Selective Estrogen Receptor Modulator
Action: Effects some of the same receptors as estrogen, but not all. Acts like estrogen to prevent bone loss and improve lipid profiles but has potential to block estrogen effects such as those causing breast and uterine cancer.
Use: Prevention of osteoporosis in postmenopausal women.
Dental Considerations: Local anesthesia with vasoconstrictor ok. Sinusitis, pharyngitis, arthralgia, myalgia.
Dental Drug Interactions: None reported yet of clinical significance.
Gonadotropin Releasing Hormone
Action: Suppresses ovarian and testicular steroidogensis due to decreased levels of LH and FSH. Decreases levels of testosterone (male) and estrogen (female) hormones.
Use: Treat precocious puberty. Palliative treatment of advanced prostate carcinoma.
Dental Considerations: Local anesthesia with vasoconstrictor ok. Headache, paresthesia and myalgia.
Dental Drug Interactions: None
Action: Competes with histamine for H-1 receptor sites in GI tract, blood vessels and respiratory tract. Net result is a decreased allergic response.
Use: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis (sneezing, rhinorrhea, lacrimation and pruritis) and chronic urticaria.