Nigrostriatal pathway (upper left box) Substantia Nigra to Striatum. Motor control. Death of neurons in this pathway can result in Parkinson's Disease Tuberoinfundibular pathway



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You can think of a brain pathway as a power line that connects two brain regions. Brain pathways are made up of interconnected neurons along which signals are transmitted from one brain region to another.



Brain region 1

Brain region 2

Brain region 3



Interconnected neurons form brain pathways which allow communication between different brain regions.


Dopamine is the neurotransmitter used by the reward pathway (also called the mesolimbic pathway, which is closely associated with the mesocortical pathway). But there are two other important pathways in the brain that utilize dopamine: the nigrostriatal pathway and the tuberoinfundibular pathway. Generally, drugs that affect dopamine levels in the brain affect all three of these dopamine pathways.




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