Modul 1General Pathomorphology Text tests



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Aorta

  • Aorta and coronary arteries

  • Pulmonary veins

  • Coronary artery

  • Where are formed hyaline thrombus:

    1. * Kappilary

    2. The right atrium

    3. Left atrium

    4. Aorta

    5. Pulmonary artery

  • Where are formed red thrombus:

    1. * Veins

    2. Aorta

    3. Pulmonary artery

    4. Arterioles

    5. Kappilary

  • Where are more frequent thrombus with ICE syndrome:

    1. Veins

    2. Emptiness of heart

    3. * Microvessels

    4. Aorta

    5. Great arteries

  • Where are the white thrombus formation:

    1. * Aorta

    2. Hollow vein

    3. Pulmonary veins

    4. Venules

    5. Kappilary

  • Where formed dilatation thrombus:

    1. Left atrium

    2. * Aneurysm

    3. The right atrium

    4. The right ventricle

    5. Left ventricle

  • Which becomes the liver in chronic venous hyperemia:

    1. Red

    2. Muscat

    3. Cyanosis

    4. Gray

    5. Pale

  • White thrombus frequently occur in:

    1. * Aorta

    2. Hollow vein

    3. Pulmonary veins

    4. Venules

    5. Kappilary

    1. "Hairy heart" is an example of which of the following types of inflammation :

      1. Purulent;

      2. * Fibrinous;

      3. Serous;

      4. Catarrhal;

      5. Hemorrhagic.

    2. Abscess of the lung is an example of which of the following types of inflammation:

      1. *Purulent;

      2. Fibrinous;

      3. Serous;

      4. Catarrhal;

      5. Granulomatous.

    3. Activation of Hageman factor leads to activation of all of the following catalytic systems, EXCEPT:

      1. The complement system;

      2. * P-450 ( mixed-function oxidase system );

      3. Kinin system;

      4. Fibrinolytic system;

      5. Coagulation system.

    4. Acute gastritis with abundant mucus production is an example of which of the following types of inflammation:

      1. Purulent

      2. Fibrinous

      3. Serous

      4. *Catarrhal

      5. Granulomatous

    5. Acute inflammation includes all of the following types, EXCEPT:

      1. Purulent

      2. Fibrinous

      3. *Granulomatous

      4. Serous

      5. Catarrhal.

    6. Acute inflammation is characterized by all of the following features, EXCEPT:

      1. Relatively short duration

      2. * Immigration of lymphocytes into theinjured area

      3. Immigration of leukocytes into the injured area

      4. Exudation of fluid

      5. Exudation of plasma proteins.

    7. AH of the following factors promote neutrophil immigration into tissues during acute inflammatory responses, EXCEPT:

      1. Leukotriene B4;

      2. *Nitric oxide;

      3. ntercellular adhesion molecule-1;

      4. Complement fragment C5a;

      5. Platelet-activating factor.

    8. All of the following statements describing leukocyte emigration from vessels in areas of inflammation are true, EXCEPT:

      1. Leukocytes pass through gaps between thevascular endothelial cells;

      2. Neutrophils are the first cells to emigrate;

      3. Leukocytes develop pseudopods to aid inemigration;

      4. * Lipofuscin accumulation accompaniesleukocyte emigration;

      5. Accompanying loss of red cells is passive.

    9. All of these cells can be found in sarcoid granuloma, EXCEPT:

      1. Clusters of epithelioid cells

      2. Langhans-type giant cells

      3. Macrophages

      4. *Granulocyte

      5. Lymphocytes

    10. An 8-year-old child was done an intracutaneous tuberculin (Mantoux) test with a diagnostic purposE. Forty-eight hours following the injection of tuberculin, a dense hyperaemic papule, 20 cm in diameter, with necrosis in its centre formeD. Name the mechanism of hypersensitivity which lay in the basis of the above changes.:

      1. Immunocomplex cytotoxicity

      2. Anaphylaxis

      3. Antibody-dependent cytotoxicity

      4. *Cellular cytotoxicity

      5. Granulomatosis

    11. Anti-inflammatory drugs such as aspirin and indomethacin (non-steroidal drugs) inhibit:

      1. Lymphokine production

      2. Lysosomal degradation

      3. * Leukotriene and prostaglandin production

      4. Vasoactive amine release

      5. Fibronectin production.

    12. At the skin sarcoidosis can be found the type of necrosis as:

      1. Coagulation necrosis

      2. Liquefaction necrosis

      3. Enzymatic fat necrosis

      4. Caseous necrosis

      5. *Fibrinoid necrosis

    13. Cardinal signs of acute inflammation include all of the following, EXCEPT:

      1. Local heat;

      2. Redness;

      3. * Pallor;

      4. Swelling;

      5. Pain.

    14. Cell type that transforms into morphologically distinct cells capable of immunoglobulin production is which of the following:

      1. Neutrophils;

      2. Basophils;

      3. *B-cells;

      4. T-cells;

      5. NK- cells.

    15. Cells that are capable of phagocytosis of particulate matter include which of the following:

      1. * Neutrophils, macrophages

      2. Lymphocytes, mast cells

      3. T-cells, NK- cells

      4. Basophils, stem cells

      5. Endothelial cells, plasma cells.

    16. Continued recruitment of monocytes from the circulation in chronic inflammation results from the expression of all of the following, EXCEPT:

      1. IL-1I

      2. CSF-GC

      3. * Oncogenes

      4. Fragments of the destroyed collagen and fibronectin

      5. Fibrinopeptides

    17. During the inflammatory response, the proper order of white cell events is:

      1. Endothelial adherence, margination,phagocytosis, chemotaxis

      2. *Margination, leukodiapedesis, chemotaxis,phagocytosis

      3. Margination, migration, chemotaxis, stasis

      4. Stasis, leukodiapedesis, margination, phagocytosis

      5. Leukodiapedesis, stasis, degranulation.

    18. Fibrinous pericarditis occurs in all diseases, EXCEPT:

      1. Acute rheumatic fever;

      2. Systemic lupus erythematosus;

      3. Uremia;

      4. *Atherosclerosis

      5. Acute myocardial infarction.

    19. Fluid that collects during acute inflammation and that has a protein content exceeding 3 g/dl and a specific gravity exceeding 1.015 is referred to as:

      1. Edema;

      2. Effusion;

      3. Transudate;

      4. Serum;

      5. *Exudate.

    20. Granuloma in primary tuberculosis is com posed predominantly of which of the following:

      1. Fibroblasts

      2. * Epithelioid cells

      3. Eosinophils

      4. Plasma cells

      5. Neutrophils

    21. Gummatous infiltrate in tertiary syphilis can be found in which of the following organs:

      1. *Aorta

      2. Testes

      3. Liver

      4. Bones and joints

      5. Skin and subcutaneous tissue

    22. In an inflammatory response, neutrophils release molecules that induce all of the following effects, EXCEPT:

      1. Chemotaxis of monocytes

      2. *Chemotaxis of lymphocytes

      3. Degranulation of mast cells

      4. Increased vascular permeability independentof histamine release

      5. Connective tissue digestion.

    23. Inflammatory infiltrate associated with an acute bacterial bronchopneumonia consists predominantly of which of the following cells:

      1. Eosinophils

      2. Lymphocytes

      3. Monocytes/macrophages

      4. *Neutrophils

      5. Plasma cells.

    24. Inflammatory response leads to all of the following, EXCEPT:

      1. Isolation of infected tissues

      2. Inactivation of causative agents

      3. Neutralization of toxins

      4. Removal of devitalized tissue debris

      5. *Obesity.

    25. It is know that during the inflammatory response, the proper order of white cell events is:

      1. Endothelial adherence, margination,phagocytosis, chemotaxis;

      2. *Margination, leukodiapedesis, chemotaxis,phagocytosis;

      3. Margination, migration, chemotaxis, stasis;

      4. Stasis, leukodiapedesis, margination, phagocytosis;

      5. Leukodiapedesis, stasis, degranulation.

    26. It is know that in an inflammatory response, neutrophils release molecules that induce all of the following effects, EXCEPT:

      1. Chemotaxis of monocytes;

      2. *Chemotaxis of lymphocytes;

      3. Degranulation of mast cells;

      4. Increased vascular permeability independentof histamine release;

      5. Connective tissue digestion.

    27. Lobar pneumonia is an example of which of the following types of inflammation:

      1. Purulent;

      2. Fibrinous;

      3. Serous;

      4. Catarrhal;

      5. Granulomatous.

    28. Lysosomes within neutrophils contain all of the following enzymes, EXCEPT:

      1. Myeloperoxidase;

      2. Acid hydrolases;

      3. Proteases;

      4. * Interleukin-2;

      5. Cationic proteins.

    29. Macrophages in granulomatous inflammation can transform into which of the following cells:

      1. Monocytes

      2. Epithelial cells

      3. *Epithelioid cells

      4. Plasma cells

      5. Lymphocytes

    30. Major functions of macrophages are all of the following, EXCEPT:

      1. Phagocyte function;

      2. IL - 1- synthesizing function;

      3. Secretory function;

      4. * Antibody-synthesizing function;

      5. Healing and repair function.

    31. Mediators of increased vascular permeability in acute inflammatory responses include all of the following, EXCEPT:

      1. Leukotriene E4;

      2. *Complement complex C5b-9;

      3. Leukotriene C4;

      4. Bradykinin;

      5. Platelet-activating factor.

    32. Most comprehensively the chronic inflammation is characterized by which of the following:

      1. Infiltration with mononuclear cell including macrophages, lymphocytes, and plasma cells

      2. Tissue destruction

      3. Healing by connective tissue with angiogenesis and fibrosis

      4. *A11 of these

      5. None of these

    33. Name the mechanism lying in the basis of the pathogenesis of organ-specific autoimmune diseases.:

      1. *Disturbance of the physiological isolation of organs and tissues to which there is no physiological tolerance

      2. Primary disturbance in the immunocompetent system

      3. Appearance of new nonshared antigens in the organism

      4. Disturbance in the control of immune homeostasis

      5. Atrophy of the lymphoid system

    34. On gross inspection, syphilitic gumma is characterized by all of the following features, EXCEPT:

      1. White-gray

      2. Rubbery

      3. Solitary

      4. *Red-brown

      5. Tumor-like

    35. Plasma factors to be released during inflammation are all of the following, EXCEPT:

      1. Bradykinin;

      2. Membrane attack sequence;

      3. *Cationic proteins;

      4. Thrombin;

      5. Plasmin.

    36. Products released by the activated macrophages, that lead to fibrosis include all of the following, EXCEPT:

      1. Growth factors

      2. Fibrogenic cytokines

      3. Angiogenesis factors

      4. Fibronectin

      5. *Proteases

    37. Purulent inflammation is characterized by which of the following:

      1. Fibrin deposition;

      2. Mucus production;

      3. Lymphocyte infiltration;

      4. *Neutrophil infiltration;

      5. Red cell infiltration.

    38. Sarcoidisis development is associated with which of the following:

      1. Mycobacterium leprae

      2. Mycobacterium tuberculosis

      3. Treponema pallidum

      4. Gram-negative bacillis

      5. *Unknown

    39. Syphilis granuloma is also called as:

      1. Fibroma

      2. * Gumma

      3. Tuberculoma

      4. Leproma

      5. Hepatoma

    40. The "Hairy heart" is an example of which of the following types of inflammation :

      1. Purulent

      2. *Fibrinous

      3. Serous

      4. Catarrhal

      5. Hemorrhagic.

    41. The abscess which situated in lung is an example of which of the following types of inflammation:

      1. * Purulent

      2. Fibrinous

      3. Serous

      4. Catarrhal

      5. Granulomatous.

    42. The acute form of inflammation is characterized by all of the following features, EXCEPT:

      1. Relatively short duration;

      2. * Immigration of lymphocytes into theinjured area;

      3. Immigration of leukocytes into the injured area;

      4. Exudation of fluid;

      5. Exudation of plasma proteins.

    43. The adherence of neutrophils and monocytes to the vascular endothelium prior to movement into the extravascular space is called:

      1. Margination;

      2. Diapedesis;

      3. * Pavementing;

      4. Emigration;

      5. Clotting.

    44. The AH of the following factors promote neutrophil immigration into tissues during acute inflammatory responses, EXCEPT:

      1. Leukotriene B4

      2. *Nitric oxide

      3. Intercellular adhesion molecule-1

      4. Complement fragment C5a

      5. Platelet-activating factor.

    45. The all of these cells can be found in chronic inflammation infiltrate, EXCEPT:

      1. Lymphocytes

      2. *Platelets

      3. Macrophages

      4. Plasma cells

      5. Eosinophils

    46. The Anti-inflammatory drugs such as aspirin and indomethacin (non-steroidal drugs) inhibit:

      1. Lymphokine production;

      2. Lysosomal degradation;

      3. *Leukotriene and prostaglandin production;

      4. Vasoactive amine release;

      5. Fibronectin production.

    47. The cell type that transforms into morphologically distinct cells capable of immunoglobulin production is which of the following:

      1. Neutrophils

      2. Basophils

      3. * B-cells

      4. T-cells

      5. NK- cells.

    48. The cells that are capable of phagocytosis of particulate matter include which of the following:

      1. * Neutrophils, macrophages;

      2. Lymphocytes, mast cells;

      3. T-cells, NK- cells;

      4. Basophils, stem cells;

      5. Endothelial cells, plasma cells.

    49. The first cells to arrive at the injured area in the inflammatory response are which of the following:

      1. * Neutrophils;

      2. Fibroblasts;

      3. Lymphocytes;

      4. Macrophages;

      5. Erythrocytes.

    50. The fluid that collects during acute inflammation and that has a protein content exceeding 3 g/dl and a specific gravity exceeding 1.015 is referred to as:

      1. Edema

      2. Effusion

      3. Transudate

      4. Serum

      5. * Exudate.

    51. The foreign-body granulomas are caused by all the following, EXCEPT:

      1. Particulate matter

      2. Synthetic material

      3. * Gram-negative bacillus

      4. Vegetable matter

      5. Beryllium particles.

    52. The granuloma in sarcoidosis is composed predominantly of which of the following:

      1. * Monocytes/macrophages

      2. Neutrophils

      3. Eosinophils

      4. Plasma cells

      5. Lymphocytes/fibroblasts

    53. The granulomatous cell infiltrate in primary syphilis is composed predominantly of which of the following:

      1. Neutrophils

      2. Monocytes/macrophages

      3. * Plasma cells

      4. Eosinophils

      5. Lymphocytes

    54. The granulomatous inflammation develops in all of the following diseases, EXCEPT:

      1. Tuberculosis

      2. Leprosy

      3. Syphilis

      4. Cat-scratch disease

      5. * Budd-Chiary syndrome

    55. The Hageman factor Activation leads to activation of all of the following catalytic systems, EXCEPT:

      1. The complement system

      2. * P-450 ( mixed-function oxidase system )

      3. Kinin system

      4. Fibrinolytic system

      5. Coagulation system.

    56. The inflammatory infiltrate associated with an acute bacterial bronchopneumonia consists predominantly of which of the following cells:

      1. Eosinophils;

      2. Lymphocytes;

      3. Monocytes/macrophages;

      4. * Neutrophils;

      5. Plasma cells.

    57. The inflammatory response leads to all of the following, EXCEPT:

      1. Isolation of infected tissues;

      2. Inactivation of causative agents;

      3. Neutralization of toxins;

      4. Removal of devitalized tissue debris;

      5. * Obesity.

    58. The leukocyte emigration from vessels in areas of inflammation are described by all of the following statements, EXCEPT:

      1. Leukocytes pass through gaps between thevascular endothelial cells

      2. Neutrophils are the first cells to emigrate

      3. Leukocytes develop pseudopods to aid inemigration

      4. * Lipofuscin accumulation accompaniesleukocyte emigration

      5. Accompanying loss of red cells is passive.

    59. The lobar pneumonia is an example of which of the following types of inflammation:

      1. Purulent

      2. *Fibrinous

      3. Serous

      4. Catarrhal

      5. Granulomatous.

    60. The lungs with multiple tuberculous granulomas are called as:

      1. Tuberculous pneumonia

      2. Brown induration of lungs

      3. *Miliary tuberculosis

      4. Cavitary fibrocaseous tuberculosis

      5. Tuberculoma

    61. The lysosomes within neutrophils contain all of the following enzymes, EXCEPT:

      1. Myeloperoxidase

      2. Acid hydrolases

      3. Proteases

      4. * Interleukin-2

      5. Cationic proteins.

    62. The major functions of macrophages are all of the following, EXCEPT:

      1. Phagocyte function

      2. IL - 1- synthesizing function

      3. Secretory function

      4. *Antibody-synthesizing function

      5. Healing and repair function.

    63. The medial destruction of aorta in tertiary syphilis may lead to which of the following:

      1. * Aneurismal dilatation of the aorta

      2. Marian's syndrome

      3. Atherosclerosis

      4. Takayasu's arteritis

      5. Giant cell arteritis

    64. The mediators of increased vascular permeability in acute inflammatory responses include all of the following, EXCEPT:

      1. Leukotriene E4

      2. * Complement complex C5b-9

      3. Leukotriene C4

      4. Bradykinin

      5. Platelet-activating factor.

    65. The miliary lung tuberculosis is characterized by which type of inflammation:

      1. * Granulomatous

      2. Serous

      3. Fibrinous

      4. Supurative

      5. Hemorrhagic

    66. The most common formation in the body cavities and the spinal fluid is which of the following:

      1. Fibrinous inflammation;

      2. * Serous inflammation;

      3. Catarrhal inflammation;

      4. Hemorrhagic inflammation;

      5. Granulomatous inflammation.

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