Isam zebeba cartilage Embryo



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Cartilage and Bone”

By:Dr.ISAM ZEBEBA



Cartilage

Embryo

More prevalent than in adult

 Skeleton initially mostly cartilage

 Bone replaces cartilage in fetal and childhood periods



Location of cartilage in adults

  1. External ear

  2. Nose

  3. “Articular” – covering the ends of most bones and movable joints

  4. “Costal” – connecting ribs to sternum

  5. Larynx - voice box

  6. Epiglottis – flap keeping food out of lungs

  7. Cartilaginous rings holding open the air tubes of the respiratory system (trachea and bronchi)

  8. Intervertebral discs

  9. Pubic symphysis

  10. Articular discs such as meniscus in knee joint


Remember the four basic types of tissue…

Epithelium

 Connective tissue

Connective tissue proper

 Cartilage

 Bone


 Blood

Muscle tissue



 Nervous tissue


Cartilage is connective tissue

  1. Cells called chondrocytes

  2. Abundant extracellular matrix

 Fibers: collagen & elastin

 Jellylike ground substance of complex sugar molecules

 60-80% water (responsible for the resilience)

 No nerves or vessels



Types of cartilage: 3


  1. Hyaline cartilage: flexible and resilient

 Chondrocytes appear spherical

Lacuna – cavity in matrix holding chondrocyte

 Collagen the only fiber


  1. Elastic cartilage: highly bendable

 Matrix with elastic as well as collagen fibers

Epiglottis, larynx and outer ear



  1. Fibrocartilage: resists compression and tension

 Rows of thick collagen fibers alternating with rows of chondrocytes (in matrix)

 Knee menisci and annunulus fibrosis of intervertebral discs



Hyaline Cartilage



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