I V course / educ years The plan of lectures on medical biology and genetics for the students of I course of stomatology faculty



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thematical plan

of the lectures on biophysical and bioorganic chemistry for students of stomatologY faculty




Theme

Hours


1.


Content of the subject of biophysical chemistry, methods and connection with medicine. Distribution of the chemical elements in the Earth’s crust and human organism. Quantum-mechanical model of the atom structure.

2


2.

The classification of organic compounds. Monofunctional and heterofunctional organic compounds and their representatives, applicated in medicine.

2

3.

Complex compounds and the modern theories explaining their formation. Internal complex compounds.

2

4.

The basic notions and laws of chemical thermodynamics and bioenergetics. Application of the first law of thermochemistry to the biological systems. Statistical nature of entropy.Gibbs free energy. Thermodynamics of the irreversible processes.

2

5.

Carbohydrates, classification, stereoisomerism and biological role.

2

6.



Solutions. Diffusion and osmosis. Donnan’s equilibrium. Electrochemistry of biological systems. Chemical kinetics. Enzymes as the catalysts of the biochemical reactions. Kinetics of fermentative reactions.

2



7.

α-Aminoacids, classification, stereoisomerization and properties. Peptides and proteins, their biological functions and structure

properties.



2

8.

Dispersed systems and their properties. Coagulation, its kinetics and the main theories. The physical chemistry of biopolymer solutions.

2

9.

Heterocyclic compounds, classification, properties and important derivatives applicated in medicine.

2

10.

Lipids. Unsaponifiable lipids. Terpens and terpenoids. Steroids and bile acids.

2



thematical plan

of the practical lessons on biophysical chemistry for students of the

STOMATOLOGy faculty



Theme

Hours


1

The modes of expression the concentration of the solutions. Volumometric analysis. Method of neutralization. Alkalimetry and acidimetry.

Lab.w. The preparation of sodium tetraborate (borax) solution with known titre and determination of HCl concentration.



2

2

Method of oxidimetry. Permanganatometry. Iodometry.

Lab.w. The preparation of potassium bichromate solution with known titre and determination of sodium thiosulfate concentration.



2

3

The first law of thermodynamics (internal energy, enthalpy). Thermochemistry.Respiratory and caloric coefficients. Hess’s law and decision of tasks on thermochemistry.

2

4

Test.(Chemical elements. Atomic structure. Complex compouds. Thermodynamics.)

2

5

The colligative properties of the solutions. Raoult’s law.

Methods of cryoscopy, ebullioscopy and osmometry. Hydrogen ion exponent (pH). Buffer systems.

Decision of the tasks on the calculation of molecular mass (seminar).


2

6

Rate of chemical reactions, molecularity and order. Influence of temperature on reaction rate. Radiation reactioms.

Calculation of the reaction order and activation energy of the chemical reactions.



2

7

Test. Solutions, colliqative properties electrochemistry of biological systems, Chemical kinetics and enzymatic reactions.

2

8

Surface phenomena. Surface tension. Adsorption at the border of solid-liquid. Chromatography and its kinds.

Division of composition on the components and analysis of aminoacids mixture by method of paper chromatography.



2

9

Dispersed systems. Coalulations kinetic and mechanism biopolumers,stability of their solutions.

2

10

Test. Surface phenomena. Adsorption. Chromatography. Dispersed systems.Polumer solutions.

1

11

Final lesson.

1
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