Histopathology



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Histopathology

Exam 1


1-28-08

Dental Questions




  1. According to you testbook, the germ layers (i.e., ectoderm, mesoderm, and endoderm) mature and differentiate into specific tissues and organ systems during the ________ period of development.

    1. Implantation period

    2. Proliferation period

    3. Embryonic period

    4. Fetal development period




  1. All the following are derived from neural crest cells EXCEPT:

    1. Melanocytes

    2. Enamel

    3. Sympathetic neurons

    4. Cartilages of the face




  1. In lecture, a “cyst” was defined as:

    1. A cavitated area in the body (either empy or fluid-filled), lined with cells

    2. A metastatic growth resistant to radiation treatment

    3. A well circumscribed radioleucent lesion on a radiograph

    4. A large swelling the midline of the neck

  2. The palatine shelves complete fusion during the ____ and ____ week.

    1. 4th – 5th

    2. 6th – 7th

    3. 8th – 9th

    4. 10th – 12th




  1. The thyroid gland invaginates at the ________.

    1. Copula

    2. Tuberculum impar

    3. Hypobranchial eminence

    4. Foramen cecum




  1. Which of the following cranial nerves gives special sensory (taste) functions in the anterior 2/3 of the tongue?

    1. Trigeminal (C-V)

    2. Facial (C-VII)

    3. Glossopharyngeal (C-IX)

    4. Vegas (C-X)

    5. Hypoglossal (C-XII)


  1. The parathyroid glands are derived from the ectoderm lining pharyngeal ______.

    1. Pouches I and II

    2. Arches II and III

    3. Pouches III and IV

    4. Arches IV and V




  1. If cells that give rise to the thyroid gland fail to migrate from their site of origin, at which of the following anatomical sites would you least likely find the ectopic thyroid?

    1. Anterior to the hyoid bone

    2. Neck, adjacent to the sternocleidomastoid muscle

    3. Anterior to the cricoid cartilage

    4. Posterior dorsal surface of the tongue




  1. The embryonic mesoderm cell layer is derived from the ________ layer.

    1. Ectoderm

    2. Syntrophoblast

    3. Endoderm

    4. Hypoblastic




  1. Implantation of the embryoblast into the uterine wall begins at day ____ following conception, and is completed by day ____.

    1. 2 / 6

    2. 2 / 8

    3. 4 / 10

    4. 5 / 12

    5. 6 / 14




  1. Complete the following equation (pre-tooth bud stage of development): 1st Branchial Arch Epithelium + 2nd Brancial Arch Mesenchyme =

    1. Tooth

    2. Skin

    3. Melanocytes

    4. Thyroid tissue

    5. Oreo cookies




  1. Which of the following are precursors of the vertebral column, ribs, associated back muscles and overlying dermis:

    1. Prechordal plates

    2. Primitive nodes

    3. Lateral plate mesoderm

    4. Somites


  1. The following is an accurate description of which of the listed neural tube defects? “Extrusion (herniation) of neural tissue, plus a portion of the meninges, through the fetal cranium.”

    1. Spina Bifida

    2. Meningocele

    3. Meningomyelocele

    4. Meningoencephalocele




  1. Cleft lip results when there is a lack of fusion between the ________ and ________ processes.

    1. Medial nasal, mandibular

    2. Lateral nasal, mandibular

    3. Medial nasal, maxiallary

    4. Lateral nasal, maxiallary




  1. A dilacerations is caused by a deviation in growth of which of the following:

    1. Cervical loop

    2. Epithelial Diaphragm

    3. Hertwig’s root sheath

    4. Heuser’s membrane




  1. The posterior 1/3 of the tongue is derived from the ________ of the ________ pharyngeal arch.

    1. Hypobranchial eminence / 3rd

    2. Hypobranchial eminence / 1st

    3. Tuberculum impar / 2nd

    4. Lateral lingual swellings / 1st

    5. Lateral lingual swellings / 3rd




  1. Which of the following statements regarding Median Rhomboid Glossitis is true:

    1. It is thought to be a remnant of the 2nd pharyngeal arch

    2. It is seen clinically as a “bald spot” on the lateral surface of the tongue

    3. It is thought to have an association with the HPV virus

    4. It is thought to be caused by the lack of overgrowth of the 4th pharyngeal arch




  1. According to the textbook (Berkowitz, et al.), the hard palate ossifies intramembranously from ____ centers of ossification.

    1. 2

    2. 3

    3. 4

    4. 5


  1. The anterior 2/3 of the tongue is derived from which pharyngeal arch/intermediate structure combination?

    1. 3rd arch / hypobranchial eminence

    2. 1st arch / tuberculum impar

    3. 2nd arch / copula

    4. 1st arch / foramen cecum

    5. 1st arch / lateral lingual swellings




  1. The tongue receives innervation from all of the following cranial nerves EXCEPT:

    1. Trigeminal (C-V)

    2. Facial (C-VII)

    3. Glossopharyngeal (C-IX)

    4. Abducens (C-VI)

    5. Hypoglossal (C-XII)

For the following questions, match the developmental structures with their appropriate pharyngeal arch. (choices can be used more than once):




    1. Pharyngeal Arch #1

    2. Pharyngeal Arch #2

    3. Pharyngeal Arch #3

    4. Pharyngeal Arch #4

    5. Pharyngeal Arch #6

21. _____ Trigeminal nerve (C-V)

22. _____ Vagus nerve (C-X)

23. _____ Hypoglossal nerve (C-XII

24. _____ Styloid process

25. _____ Incus bone

26. _____ Thyroid cartilage

27. _____ Sensory innervation to posterior 1/3 of the tongue


For the following questions, match the developmental structures with their appropriate pharyngeal cleft of pouch of origin (choices can be used more than once):


    1. Pharyngeal cleft #1

    2. Pharyngeal pouch #1

    3. Pharyngeal pouch #2

    4. Pharyngeal pouch #3

    5. Pharyngeal pouch #4

28. _____ palatine tonsil

29. _____ ultimobranchial body

30. _____ external auditory meatus

31. _____ inferior parathyroids

32. _____ thymus

33. _____ Eustachian tube


  1. At 3 months of fetal development, the head lenth relative to total trunk (i.e. thorax and abdomen) length is approximately ____ %

    1. 20

    2. 30

    3. 40

    4. 50




  1. According to your text, which of the following statements concering spina bifida is correct?

    1. Spina bifida results from the defective closure of the dorsal aspect of the caudal half of the neural tube

    2. Development of spina bifida occurs between the 4th to 5th month

    3. Spina bifida can be prodcuced by a lack of vitamin A in laboratory animals

    4. Spina bifida is thought to be a result of folic acid excess in the mother

For the following questions, match the stages of tooth development with their appropriate cellular activity (choices can be used more than once).




    1. Cellular induction

    2. Cellular proliferation

    3. Proliferation, Differentiation, and Mophogenesis

    4. Induction and Proliferation

    5. Maturation




  1. _____ Initiation

  2. _____ Apposition

  3. _____ Bell Stage

  4. _____ Maturation

  5. _____ Bud Stage

  6. _____ Cap Stage

  7. Post tooth-bud stage, which of the following equations would be correct:

    1. Tooth epithelium + Skin mesenchyme = Tooth

    2. Tooth epithelium + Skin mesenchyme = Skin

    3. Skin epithelium + Tooth mesenchyme = Skin




  1. The “enamel organ” consists of all of the following EXCEPT:

    1. Stellate Reticulum

    2. Stratum Intermedium

    3. Outer Dental Epithelium

    4. Dental Follicle

    5. Inner Dental Epithelium




  1. The dental follicle differentiates into all the following adult tissues EXCEPT

    1. Periodontal ligament (PDL)

    2. Cementum

    3. Alveolar Bone

    4. Pulp




  1. Embryologically, the “enamel organ” is derived from the ________.

    1. Hypoblast

    2. Ectoderm

    3. Endoderm

    4. Neural crest

For the following questions, match the list of tissues with their cell layer of origin (choices can be used more than once).




  1. Enamel

  2. Alveolar bone

  3. Dentinoenamel junction (DEJ)

  4. Dentin

  5. Dental Pulp




  1. _____ Odontoblasts

  2. _____ Dental Papilla

  3. _____ Ameloblasts

  4. _____ Dental Sac

  5. _____ Basement Membrane




  1. With respect to the tooth root, the epithelial diaphragm determines their _-______.

    1. Shape

    2. Number

    3. Diameter

    4. Curvature




  1. The stratum intermedium secretes ________, an enzyme required for enamel matrix mineralization.

    1. Acid phophatase

    2. Pyrophophatase

    3. Alkaline phosphatase

    4. What-the-freak phosphatase




  1. A patient presents with a “doubled” central incisor, however, when counting the teeth, the tooth count is less by one tooth when the “double tooth” is counted as one. What is the diagnosis?

    1. Fusion

    2. Gemination

    3. Taurodontism

    4. Concrescence

    5. Hypodontia




  1. Nasmyth’s membrane consists of all the following cell layers EXCEPT

    1. Reduced ameloblasts

    2. Outer enamel epithelium

    3. Stellate reticulum

    4. Stratum intermedium

    5. Reduced odontoblasts




  1. A ________ is the most common manifestation of a supernumerary tooth

    1. Peg lateral incisor

    2. Mesodens

    3. 3rd bicuspid

    4. fused tooth

    5. 4th molar




  1. A ________ is comprised of enamel and dentin arranged in a way that bears an autonomic resemblance to teeth

    1. Complex odontoma

    2. Ameloblastoma

    3. Compound odontoma

    4. Odontogenic keratocyst




  1. A patient presents with a radiograph that that shows the roots of multiple mandibular teeth joined together by cementum. What would your diagnosis be?

    1. Taurodontism

    2. Fusion

    3. Gemination

    4. Concrescence




  1. The dentigerous cysts comprises ____% of all jaw cysts and is always associated with a/an ________.

    1. 20 / fully erupted tooth

    2. 20 / attachment to the CEJ

    3. 10 / carious tooth

    4. 10 / detachment of the dental follicle


  1. A developmental cyst occurring along the lateral aspect of the neck is mostly likely a

    1. Thyroglossal duct cyst

    2. Lateral periodontal cyst

    3. Lateral cervical cyst

    4. Posterior mandible



  2. Most odontogenic keratocysts (OKC’s) occur in the ________.

    1. Anterios maxilla

    2. Posterior maxilla

    3. Anterior mandible

    4. Posterior mandible




  1. Upon biopsy, the lumen of the odontogeic keratocyst is characterized by the presenece of:

    1. Keratin

    2. Empty space

    3. Fluid

    4. Tissues of the tooth (enamel, dentin, et.)




  1. The most commone neoplastic lesion of the jaws, arising from the odontogenic epithelium is the ________.

    1. Odontoma

    2. Osteogenic sarcoma

    3. Fibrosarcoma

    4. Ameloblastoma




  1. Cranial Nerve IX is responsible for which of the following:|

    1. Sensory to the anterior 2/3 of the tongue

    2. Sensory to the posterior 1/3 of the tongue

    3. Sensory to the extreme posterior via the superior laryngeal branch

    4. Motor innervation to the tongue muscles

ANSWERS:


  1. c

  2. b

  3. a

  4. d

  5. d

  6. b

  7. c

  8. b

  9. a

  10. c

  11. a

  12. d

  13. c

  14. c

  15. c

  16. a

  17. a

  18. c

  19. e

  20. d

  21. a

  22. d

  23. e

  24. b

  25. a

  26. d

  27. c

  28. c

  29. e

  30. a

  31. d

  32. d

  33. b

  34. d

  35. a

  36. a

  37. d

  38. e

  39. e

  40. b

  41. c

  42. b

  43. d

  44. d

  45. b

  46. d

  47. e

  48. a

  49. b

  50. c

  51. b

  52. c

  53. a

  54. e

  55. b

  56. c

  57. d

  58. b

  59. c

  60. d

  61. a

  62. d

  63. b



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