Epidural hematomas are frequently followed by Skull fractures



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*Brainstem compression

  • With agenesis of the corpus callosum, magnetic resonance imaging (MRI) will reveal

    1. Atrophy of the frontal lobes

    2. *Abnormally shaped lateral and third ventricles

    3. Cerebellar aplasia

    4. Schizencephaly

    5. Encephaloclastic porencephaly

  • Congenital hydrocephalus may develop as a consequence of which first-trimester maternal disorder?

    1. Complicated migraine

    2. *Viral infection

    3. Pseudotumor cerebri

    4. Chorea gravidarum

    5. Intervertebral disk herniation

  • Uncorrected congenital hydrocephalus will usually produce which of the following?

    1. Dolichocephaly

    2. Brachycephaly

    3. Holoprosencephaly

    4. *Macrocephaly

    5. Microcephaly

  • Adenoma sebaceum of the face is especially common with which of the following diseases?

    1. Neurofibromatosis

    2. Sturge-Weber syndrome

    3. *Tuberous sclerosis

    4. Ataxia telangiectasia

    5. Fragile X syndrome

  • Calcifications evident on the skull x-ray or CT scan of a patient with tuberous sclerosis usually represent

    1. *Calcified subependymal glial nodules

    2. Calcified meningeal adhesions

    3. Meningeal psammoma bodies

    4. Calcified astrocytomas

    5. Calcified granulomas

  • The treatment of choice for children with infantile spasms is

    1. Carbamazepine (Tegretol)

    2. Phenobarbital

    3. Phenytoin (Dilantin)

    4. Divalproex sodium (Depakote)

    5. *Adrenocorticotropic hormone (ACTH)

  • The newborn infant with motor neuron disease is likely to exhibit

    1. Seizures

    2. *Hypotonia

    3. Hypsarrhythmia

    4. Mora reflexes

    5. Spina bifida

  • Many children with Tay-Sachs disease develop blindness before they die, with retinal accumulation of gangliosides that produces

    1. Optic neuritis

    2. *Cherry red spots

    3. Chorioretinitis

    4. Retinal detachments

    5. Waxy exudates

  • Porencephaly usually develops as a consequence of

    1. Fetal alcohol syndrome

    2. *Vascular or other destructive injuries to the fetal brain

    3. Trisomy 13

    4. Trisomy 21

    5. Dandy-Walker syndrome

  • What percentage of patients with tuberous sclerosis have mental retardation?

    1. 1

    2. 10

    3. 25

    4. *65

    5. 99

  • The most obvious site of disease in myasthenia gravis is the

    1. Anterior horn cell

    2. *Neuromuscular junction

    3. Sensory ganglion

    4. Parasympathetic ganglia

    5. Sympathetic chain

  • The most common manifestation of muscle weakness with myasthe¬≠nia gravis is

    1. Diaphragmatic weakness

    2. Wristdrop

    3. Footdrop

    4. *Ocular muscle weakness

    5. Dysphagia

  • Duchenne muscular dystrophy is a sex-linked disorder involving the gene responsible for the synthesis of

    1. Glucose-6-phosphatase

    2. Hexosaminidase B

    3. Myosin

    4. *Dystrophin

    5. Act in

  • Duchenne dystrophy affects approximate

    1. 1 in 3,000 infants

    2. *1 in 3,000 male infants

    3. 1 in 30,000 infants

    4. 1 in 30,000 male infants

    5. 1 in 50.000 infants

  • For a female child to have Duchenne dystrophy she must have

    1. *Turner syndrome (XO)

    2. Klinefelter syndrome (XXY)

    3. Two affected parents

    4. An affected father

    5. An affected brother

  • The spontaneous mutation rate for the dystrophin gene is presumed to be high because

    1. *Men with Duchenne dystrophy do not reproduce

    2. The incidence of Duchenne dystrophy is increasing

    3. Numerous birth defects occur in families with Duchenne dystrophy

    4. Men may become symptomatic after adolescence

    5. Genetic studies of eggs in human ovaries reveal an excess of abnormal dys­trophin genes

  • Intellectual function in children with Duchenne dystrophy is usually

    1. Markedly impaired

    2. *Slightly impaired

    3. Normal

    4. Slightly better than that of the general population

    5. Markedly superior to that of the general population

  • With Duchenne dystrophy pseudohypertrophy routinely

    1. Does not occur

    2. Is limited to the shoulder girdle

    3. Is limited to the hip girdle

    4. *Is limited to the calf muscles

    5. Is limited to the thigh muscles

  • The shortest life expectancy is associated with which clinical sign in amyotrophic lateral sclerosis?

    1. Atrophy of the interossei

    2. Atrophy of the gastrocnemius

    3. Fasciculations in the lumbrical muscles

    4. Atrophy of the pectoralis muscles

    5. *Fasciculations in the tongue

  • Triorthocresyl phosphate (TOCP) is an organophosphate that may cause lethal neurologic complications by

    1. Eliciting massive intracerebral edema

    2. *Causing a severe motor polyneuropathy

    3. Producing widespread CNS demyelination

    4. Allowing CNS infections secondary to generalized immunosuppression

    5. Inducing status epilepticus

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