Curriculum vitae



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CURRICULUM VITAE



Carol T. Walsh, Ph.D.
ADDRESS:
Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, 72 East Concord St., R610, Boston, MA 02118

617-638-4326, 617-638-5254 (FAX), ctwalsh@bu.edu


EDUCATION:
Ph.D., Pharmacology, 1972, Boston University, Boston, MA

A.B., Biology, 1967, Radcliffe College, Cambridge, MA


ACADEMIC APPOINTMENTS:
Professor of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, 2004-present

Associate Professor of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, 1985-2004

Assistant Professor of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, 1972-1985
AWARDS AND HONORS:
Thomas Robitscher Faculty Award for Excellence in Teaching of Preclinical Sciences, Boston University School of Medicine, 1993

Proctor and Gamble Teaching Award, Class of 1994, Boston University Goldman School of Graduate Dentistry

Stanley L. Robbins Award for Excellence in Teaching, Boston University School of Medicine, 1995

Spencer N. Frankl Excellence in Teaching Award, Boston University Henry M. Goldman School of Dental Medicine, 2010


NASA Predoctoral Fellowship (1967-70)

NIH Predoctoral Fellowship (1970-72)

Research Starter Grant, Pharmaceutical Manufacturers' Association Foundation, 1973-75

Young Environmental Scientist Health Research Grant, National Institute of Environmental Health Sciences, 1978-81

Institutional Grant, American Cancer Society, 1978-79

Biomedical Research Support Grants, 1976-77, 1981-82

Research Grants, Miles Laboratories, Inc., 1982-89

National Institute of Environmental Health Sciences Research Grant, 1982-85

U.S. Department of Energy Award, 1989-1992

International Lead Zinc Research Organization Award, 1991

F.D.A. Research Grant Subcontract, 1992-1995
COMMITTEE ASSIGNMENTS (since 1985):

Department of Pharmacology and Experimental Therapeutics


Pharmacology Department Committee on Graduate Education, 1973-present, Chairman, 1989-present

Program Committee on Graduate Education, NIGMS Biomolecular Pharmacology Training Program, 1997-present

Doctoral Qualifying Examinations including service as Chair: more than 35 candidates

Dissertation Defense Committees (>32 candidates): Hubner, Ryden (first reader), Izenwasser, Harnett (first reader), Rosenbaum, Lin, Thorgeirsdottir, Siek, Katz, Unterwald, O'Malley, Kraus, Weaver, Kushner, Barstow, Hu, Zeng, Zimmet, Sidach, Steiger, Licata, Samii, Sadri, Simard, Anderson, Wu, Hu, Famous, Nehilla, Lopez, LaFlamme, Wei, Piche, Smith, Griset, Parker

Faculty Development Committee, 2004-present

Division of Graduate Medical Sciences


Academic Policy Committee, Division of Medical and Dental Sciences, 1986-2004

Steering Committee, 1994-present

Advisory Committee on Graduate Degree Programs, 1998-1999

Admissions Committee, MD/PhD Program, 1995-2001, 2010-present

URM Committee, 2010-present

MA Thesis Reader, MA in Medical Sciences Program: Morris, Singh, Guarino, Srinivas, Lu, Goldberg, Zimmerman, Manger, Choi



Boston University School of Medicine


Subcommittee on Appeal of the Promotions Committee, 1988-1990

Curriculum Committee, 1986-1995

Subcommittee on Integrated Problems course, 1991

Stanley Robbins Award Committee, 1996-1998

Committee on Committees, 1998-2000

Committee on Faculty Affairs, 1999-present

Chairman, Subcommittee on Teaching Resources, 2003

Chariman, Subcommittee on Educator of the Year Awards, 2008-present

Committee on Laboratory Safety, 1998-2002

Committee on Degrees with Latin Honors, 1996-2006

Chairman, 2000-2006

Ad Hoc Committee to Examine Restructuring the Curriculum, 2003

Self-Study Subcommittee on Basic Science Departments, 2002

Academy of Advisors, 2004-present

BUSMII Promotions Committee, 1992-2010

Preclinical Curriculum Subcommittee, 2004-present, Chair, 2004-2008

Medical Education Committee, 2004-present

John McCahan Medical Education Day Planning Committee, 2006-2008

Task Force on Diversity and Health Disparities, 2008-9

Task Force on Instructional Space, 2008-9



Boston University


University Council Committee on Curriculum and Degrees, 2001-2003

Faculty Council, 1988-1991, 2000-2003,

Secretary/Treasurer, 1990-1991, 2003-2004

Admissions Committee, Accelerated Medical Program, 1984-2004

Appeals Committee, Accelerated Medical Program, 1992-present

Martin Luther King and Whitney Young Fellowship Committee, 1990-present

Ad hoc Provost's Committee on Alleged Scientific Misconduct, 1998

Judge, Graduate Science & Technology Research Day, 1998-2000


Editorial Boards

Editorial Advisory Board and Reviewer, Toxicology and Applied Pharmacology, 1996-2004

Ad hoc Reviewer, Toxicological Sciences, Carcinogenesis, 2001-2004
Professional Organizations:

American Society for Pharmacology and Experimental Therapeutics, 1981-present, Committee on Educational Affairs, 1997-1999.

Society of Toxicology, 1984-2006, Metals Specialty Section, Chairperson of Nominating Committee, 1988; Secretary/Treasurer, 1989-1991, 1995-1997, Chairman, Symposium at Annual Meeting, Society of Toxicology, February 14, 1990, "Metal-induced alteration of gene expression."

Northeast Chapter Society of Toxicology, Secretary/Treasurer, 1988-1990

New York Academy of Sciences, Life Member as of 1978

AAAS, 1993-present

NIH: NCI Study Section, Possible Role of Metallothionein in Carcinogenesis, 1993

New England Annual Pharmacologists’ Meeting: meeting organizer in 1997, co-organizer in 2006, 2007, 2008



TEACHING ASSIGNMENTS:

General Medical Pharmacology, Course Manager (1994-2008) and Lecturer

Disease and Therapy, Module Co-Director of Foundations, Infectious Disease, Cardiovascular, Renal, Rheumatology, Neurology and Psychiatry (2008-present) and Lecturer

Dental Pharmacology, Course Manager (1990-1994,1997-present) and Lecturer (initiated course in 1990)

Introduction to Medical Pharmacology, Course Manager (1994-present) and Lecturer (initiated course in 1994)

Introductory Pharmacology, Course Manager and sole Lecturer (initiated course in 1996, annual through 2007)

Principles of Pharmacokinetics (initiated course in 1972, offered every other year through 2001)

Integrated Problems, Facilitator (since inception in early 1990s through 2004)

Advanced General Pharmacology, Lecturer (1993-present)

Molecular Neurobiology and Pharmacology, Lecturer (1993-present)



Dental Microbiology and Immunology, Lecturer (2003-present)
CONSULTANT:
Expert opinion on patent issues and medical malpractice.
BIBLIOGRAPHY:

Books


  1. Levine, R.R. in collaboration with C.T. Walsh and R.D. Schwartz-Bloom. Pharmacology: Drug Actions and Reactions. Parthenon Publishing, New York, Fifth Edition, 1996, Sixth Edition, 2000.

  2. C.T. Walsh and R.D. Schwartz-Bloom. Levine's Pharmacology: Drug Actions and Reactions. Taylor & Francis, Inc., London, Seventh Edition, 2005.


Book Chapters:

  1. Walsh, C.T.: Methods in Gastrointestinal Toxicology. In: Methods in Toxicology, A.W. Hayes, ed., Raven Press, 1982, 2nd edition, 1989, pp. 659-675; 3rd edition, 1994, pp. 895-916; 4th edition, pp. 1215-1240, 2001.

  2. Walsh, C.T.: Methods for the analysis of intestinal function. In: Toxicology of Intestinal Function, C.M. Schiller, ed., Raven Press, April, 1984.

  3. Walsh, C.T. Anatomical, physiological, and biochemical characteristics of the gastrointestinal tract. In: Principles of Route to Route Extrapolation for Risk Assessment. Gerrity, T.R. and Henry, C.J., eds., Elsevier, NY, 1990, pp. 33-50.

  4. Neville, M.C. and C.T. Walsh, Effects of drugs on milk secretion and composition. Bennett, P.N., ed., Drugs and Human Lactation, 2nd ed., Elsevier Science, 1996.

  5. Walsh, C.T. Toxicokinetics: Oral exposure and absorption of toxicants. In: Sipes, I.G., McQueen, C.A., Gandolfi, A. J. eds. Comprehensive Toxicology, Elsevier Science LTD, Vol 1, Ch. 3, 51-61, 1997.



Journal Articles


  1. Walsh, C.T. and Levine, R.R.: Drug absorption in rats pretreated with antibiotics. J. Pharmacol. Exp. Ther. 188: 277-286, 1974.

  2. Walsh, C.T. and Levine, R.R.: Studies of the enterohepatic circulation of morphine in the rat. J. Pharmacol. Exp. Ther. 195: 303-310, 1975.

  3. Walsh, C.T., Feierabend, J. and Levine, R.R.: The excretion of diethylstilbestrol and its uterotrophic effect in rats. Life Sci. 16: 1683-1688, 1975.

  4. Walsh, C.T., Levine, R.R. and Squires, C.: The gastrointestinal absorption of methadone in the rat. Drug Metabolism and Disposition 3: 525-529, 1975.

  5. Walsh, C.T. and Levine, R.R.: Methods for analysis of intestinal function. Environmental Health Perspectives 33: 17-23, 1979.

  6. Walsh, C.T., Craig, R.W. and Agarwal, R.P.: Increased activation of 1--D arabinofuranosylcytosine by hydroxyurea in L1210 cells. Canc. Res. 40: 3286-3292, 1980.

  7. Walsh, C.T.: The influence of age on the gastrointestinal absorption of mercuric chloride and methyl mercury chloride in the rat. Environmental Research 27: 412-420, 1982.

  8. Walsh, C.T. and Ryden, E.B.: The effect of chronic ingestion of lead on gastrointestinal transit in rats. Toxicol. Appl. Pharmacol. 75: 485-495, 1984.

  9. Walsh, C.T. and Harnett, K.M.: Inhibitory effect of lead acetate on contractility of longitudinal smooth muscle from rat ileum. Tox. Appl. Pharmacol. 83: 62-68, 1986.

  10. Lee, S.Y., Walsh, C.T., Ng, S.F. and Rogers, A.E.: Toxicokinetics of 7,12-dimethylbenz(a)anthracene (DMBA) in rats fed high lard or control diets. J. Nutr., Growth and Canc. 3: 167-176, 1986.

  11. Ryden, E.B. and Walsh, C.T.: The effect of lead on cholinergic contractile function in the rat forestomach. Toxicology 45: 65-78, 1987.

  12. Harnett, K.M., Walsh, C.T. and Zhang, L. Effects of Bay o 2752, an hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification. J. Pharmacol. Exp. Ther. 251: 502-509, 1989.

  13. Browne, T.R., Szabo, G.K., Walsh, C.T. et al. New pharmacokinetic methods II: Determination of the presence or absence of product inhibition in drugs with nonlinear pharmacokinetics. J. Clin. Pharmacol 30: 578-584, 1990.

  14. Perrine, S.P., Dover, G, Daftari, P., Walsh, C.T. et al. Isobutyramide, an orally available butyrate analogue, stimulates fetal globin gene expression in vitro and in vivo. Brit. J. Haematology, 88:555-561, 1994.



Reviews


  1. Walsh, C.T., Sandstead, H.H., Prasad, A.S., Newberne, P.M. and Fraker, P.J. Zinc: health effects and research priorities for the 1990s. Environmental Health Perspectives 102 (Suppl): 5-46, 1994.

  2. Walsh, C.T. and Neville, M.C. Effects of xenobiotics on milk secretion and composition. J. Nutr. Biochem. 5:418-441, 1994.

  3. Neville, M.C. and Walsh, C.T. Effects of xenobiotics on milk secretion and composition. Am. J. Clin. Nutr. 61:6875-6945, 1995.



Abstracts (since 1985)


  1. Walsh, C.T., Harnett, K.M. and Ryden, E.B. Lead-induced impairment of contractility in longitudinal smooth muscle from rat ileum. The Pharmacologist 27:130, 1985.

  2. Walsh, C.T. and Harnett, K.M Intestinal sucrase inhibitors and bile acid absorption in the rat. Fed Proc 45: 340, 1986.

  3. Harnett, K.M. and Walsh, C.T. Effect of BAY o 2752 on bile acid uptake from rat ileum. The Pharmacologist 29: 215, 1987.

  4. Harnett, K.M. and Walsh, C.T. ACAT inhibition: mechanism of hypocholesterolemic effect of BAY o 2752. Fed. Proc. 2(4): A618, 1988.

  5. Walsh, C.T. and Zhang, L. Inhibitory effect of Bay o 2752 on intestinal esterification of cholesterol. Gastro. 96: A535, 1989.

  6. Applications of micellar enzymology to clean coal technology. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, July 16, 1990,

  7. Applications of micellar enzymology to clean coal technology. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, June 25, 1991

  8. Sulfoxidation by chloroperoxidase in reverse micelles. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, June 15, 1992.

  9. Walsh, C.T., Gibbs, T.G., and Mair, E. Computer-based instruction in pharmacology with programmed problem sets on pharmacologic experiments and clinical cases. Basic Science Education Forum, Strategies for Integrating Clinical and Basic Sciences, Lincolnshire, IL, June 26, 1995.

  10. Hsu, C.H., Grochow, R., and Walsh, C.T. Use of a web-based survey tool to acquire medical student opinion for curriculum planning. John McCahan Medical Education Day, BUSM, June 19, 2006.


INVITED LECTURES (since 1985):


  1. Pharmacokinetics of sustained release preparations. American Cyanamid, Princeton, NJ, June 17, 1986.

  2. The Biotransformation of Xenobiotics, Boston, MA, Course on General Principles in Toxicology and Toxicologic Pathology, August 17, 1987.

  3. Mechanism of Gastrointestinal Toxicity, Society of Toxicology Continuing Education Course, Dallas, TX, Feb 17, 1988.

  4. Heavy Metal Toxicity, Occupational Toxicology Course, UMASS-Harvard Educational Research Center, June 15, 1989.

  5. The Toxicology of Cadmium, Mercury and Nickel, Harvard School of Public Health, Industrial Toxicology, ESP 233b, Jan. 3, 1989.

  6. The Toxicology of Cadmium, Mercury and Nickel, Harvard School of Public Health, Industrial Toxicology, ESP 233b, Nov 13, 1990.

  7. The Toxicology of Cadmium, Mercury and Nickel, Harvard School of Public Health, Priniciples of Toxicology course, ESP 204a,b, Nov 14, 1990.

  8. Overview of Metal-induced Alteration of Gene Expression. Organizer and Chair of Symposium, Society of Toxicology Annual Meeting, Miami Fl, Feb. 14, 1990.

  9. Anatomical, Physiological and Biochemical Characteristics of the Gastrointestinal Tract. Keynote Speaker, Workshop sponsored by EPA and ILSI, March 19, 1990, Principles of Route-to-Route Extrapolation.

  10. Applications of micellar enzymology to clean coal technology. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, July 16, 1990.

  11. Applications of micellar enzymology to clean coal technology. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, June 25, 1991.

  12. Catalytic and structural properties of chloroperoxidase in reverse micelles. University Coal Research Contractors' Review Meeting, Pittsburgh Energy Technology Center, U.S. Department of Energy, Pittsburgh, June 15, 1992.

  13. Zinc: Health Effects and Research Priorities for the ‘90s. 1993 International Zinc Conference, Scottsdale, AZ, Feb. 22, 1993.

  14. Principles of Pharmacology, Nurse Midwifery Program, BUSPH, annual lecture July, 1993-1997.

  15. Principles of Drug Metabolism, Northeastern University, Nov. 10, 1993.

  16. Mechanisms of Metal Toxicity, ACS Short Course: Chemical Mechanisms in Toxicology, San Francisco, April 30, 1999, New Orleans, November 5, 1999, San Francisco, April 28, 2000.

  17. Principles of Pharmacokinetics, Harvard Medical School-MIT HST Program, HST 150 Priniciples of Pharmacology, Cambridge, MA, annual lecture in February, 1996-present.

  18. Pharmacology of Diuretic Agents, Dartmouth Medical School, Medical Pharmacology course, Hanover, NH, annual lecture in May, 1999-present.

  19. Principles of Pharmacology and Agents affecting Skeletal Motor Function, Clinical Medicine, Sargent College, annual lecture in fall semester, 2003-present.

  1. Principles of Pharmacokinetics: Application to Protein Pharmaceuticals, CuraGen Corp., Brandford, CT, May 2002.

  2. Principles of Pharmacokinetics: Application to Protein Pharmaceuticals, Sole lecturer in all-day program, Dyax Corp., Cambridge, MA, May 2005.



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