Curriculum vitae dr Aysha Habib Khan



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CURRICULUM VITAE
Dr Aysha Habib Khan

Date of Birth: 08/06/1964

Work Address: Department of Pathology & Microbiology, Aga Khan University, Stadium Road, P.O. Box 3500, Karachi 74800 – Pakistan

Email: aysha.habib@aku.edu

Telephone: Home: (92)21-35347821

Office: (92)21-34861926/1927

Mobile: 0301-2648832
EDUCATION:


  • Fellow of College of Pathologist Pakistan (2010)

  • FCPS (Chemical Pathology), College of Physician & Surgeons, Pakistan (1999)

  • MBBS, Dow Medical College, Karachi University, Karachi, (1989)

  • HSC, St Joseph’s College, Karachi, Pakistan (1981)

  • SSC, Farhana Girls School, Karachi, Pakistan (1979)


RESEARCH INTERESTS

My research focus from 2005 onwards is on bone and mineral disorders. I use my own original approach to develop primary research questions and future direction for leading the research. Currently, I am working with many intra and inter departmental multidisciplinary collaborative teams within AKU. This research has built its authenticity both nationally and internationally as is evidenced by the awards received. I am hopeful that this research will bring a strong impact on health outcomes of bone and mineral disorders in Pakistan in time to come.


Prior to this I have researched in area of inborn errors of metabolism. Currently as I link service initiatives with research and development in the Section of Chemical Pathology, I would maintain my initial commitment and hope to expand the horizon of research in this important area of metabolic medicine.
TRAINING

  • Clinical attachment at Institute of Medical Research (IMR) for training on profiling of aminoacids and organic acids, Kuala Lumpur, Malaysia from 2nd -12th September 2012

  • Clinical attachment at Kings College Hospital in Clinical Biochemistry, NHS Trust, London from 12th June – 18th July 2007
  • Specialist Registrar, Chemical Pathology Royal Free Hospital, London, UK (Sep’04-Dec ’04)


  • Clinical Attachment, Kings College Hospital, NHS Trust, London, UK (Oct ‘03 – Sep’04)

  • Resident, Clinical Chemistry/Chemical Pathology, Aga Khan University, Karachi (1995-1999)

  • Resident Pediatrics, Aga Khan University, Karachi (1994-1995)

  • Medical Officer, Imam Zainul Abedin Hospital, Karachi (1990-1994)

  • Internship in Pediatrics, Civil Hospital, Karachi (1989-1990)


POSITIONS
  • Assistant Professor, Department of Pathology & Microbiology, AKU (July 05-To date)
  • Assistant Professor, Department of Medicine, AKU (July 08-To date)
  • Senior Instructor, Department of Pathology & Microbiology, AKU (Jan’03-June’05)

  • Instructor, Department of Pathology & Microbiology, AKU (Jan’00-Dec’03)



DISTINCTIONS (FOR ACADEMICS AND RESEARCH)

  • IOF Young Investigator Award: R990G polymorphism of calcium sensing receptor (CaSR) gene is associated with parathyroid hormone and calcium levels in subjects with vitamin D deficiency. At International Osteoporosis Foundation Regionals – 3rd Asia-Pacific osteoporosis meeting, organized in partnership with the Malaysian Osteoporosis Society (MOS) and the Osteoporosis Awareness Society of Kuala Lumpar (OASKL) that will be held in Kuala Lumpur, Malaysia on December 13-16, 2012 at Kuala Lumpur Convention Center (KLCC)

  • Best Oral Presentation: Determination of bone health status in community dwelling females in Karachi, Pakistan at Pakistan Association of Pathologist meeting 2011.

  • IOF Young Investigator Award: Determination of bone health status in community dwelling females in Karachi, Pakistan at International Osteoporosis Foundation Regionals – 1st Middle East & Africa osteoporosis meeting in Dubai (October 19-22, 2011)

  • Best Poster: Long term bone health in male renal transplant patients. Clinical Biochemistry, KingsCollegeHospital, London. Poster presentation in 3rdinternational symposium of Pakistan endocrine Society at Liaquat National Hospital on April 29th-30th at Karachi, Pakistan

  • Best Oral Presentation Mixed Array of mutations identified in 21 hydroxylase gene of patients with congenital adrenal hyperplasiain 2ndbiennial conference of Pakistan Society of Chemical Pathologist, AKU Karachi (Awarded Azhar gold medal for best paper presentation)

  • Won Merit Scholarship in MedicalSchool:

    • Third Position in 1st Professional M.B.B.S. Examination (Distinctions in Physiology and Biochemistry)

    • Sixth position in 2nd Professional M.B.B.S. Examination
    • Twenty second position in 4th Professional M.B.B.S. Examination




  • Position holder (10th) in Board examination of Higher Secondary School Certificate Examination


DISTINCTIONS (FOR TEACHING AND TRAINING)

  • Outstanding teachers award

  • Outstanding Teacher’s Award, 2009 at AKU

  • Overseas Development Award, from Association of Clinical Pathologists, UK (2007)

  • Charles Wallace Trust Scholarship, UK (2004)

  • Faculty Development Award, 2003 Metabolic Bone Disease, Kings College Hospital, NHS Trust, London, UK


TEACHING EXPERIENCE
Undergraduate Teaching
Leadership positions:

  • Chair endocrine and reproduction module (2011 – todate)

  • Chair Year-II, undergraduate curriculum (2007 – August 2011)


Membership:

  • Member of the sub-committee on review of content of undergraduate curriculum for year I & II (2011)

  • Member, curriculum committee at Aga KhanUniversity (2007 – 2011)

  • Mentor and advisor in the mentorship programof UGME (2000 – to date)

  • Founding member of the group for teaching of communication skills in UGME at AKU (2000 – to date)

  • Member of GIT and nutrition module committee (2009 – 2011)

  • Member of the foundinggroup for teaching of clinical skills to the year I &II medical student (2000 – 2003)

  • Member Year I committee (2005 – 2007)

  • Member of the endocrine and genitourinary module (2006 – 2009)

  • Member question review committee.Ideveloped/modified MCQs and SEQ questions in different module committees in the initial phase, now in use for testing the integrated concepts across YI & YII (2000 – 2003)


Module Coordination:

  • GIT and metabolism (2002)

  • Endocrine and genitourinary (2006)


Module Facilitation:

  • Introductory

  • Musculoskeletal

  • Endocrinology &metabolism

  • GIT and nutrition


Teaching undergraduate medical student in the old curriculum, including interactive large group session, holding clinic-pathological conferences (1996 -2000)
Teaching metabolic bone diseases to Phase 3 students (2000 – 2003)
Elective Medical Students:

A large number of AKU and other medical students from all over Pakistan do electives with me ranging from 2 weeks to 8 weeks. Many of them also undertake research projects and publish manuscript.


Examiner/Assessor Undergraduate Education

  • Exam coordinator MBBS Year IA (2005 – 2007)

  • Exam coordinator MBBS IB (2008)

  • Examiner of Pathology, for MBBS IA and IB examinations (2005–to date)

  • Examiner of communication skills in MBBS IA & IB examination (2005– to date)

  • Internal examiner of Pathology for final year surgical exam (2006 -2007)


Other Activities:

  • Attend annual retreats organized by DED

  • Conducted and attended retreat for review of undergraduate curriculum (2010)

  • Question review and question making for undergraduate students

  • Developed question bank for YII

  • Pathology teaching in musculoskeletal and endocrine &reproduction modules


Post Graduate Teaching
Administrative Assignments PGME

  • Director Chemical Pathology residency program, Department of Pathology & Microbiology, AKU (2006 – to date)

  • Member Departmental Residency Committee, Department of Pathology & Microbiology, AKU (2006 – to date)

  • CPSP supervisor of fellowship training program (FCPS) in Chemical Pathology, (2006 – to date). Currently, I am supervising 3 residents and one of my candidates is appointed as Instructor in the Department.

  • Assessor for theory scripts – fellowship and membership examination, at College of Physician & Surgeon, Pakistan (2007 – to date)

  • Examiner, fellowship examination FCPS Part II (Chemical Pathology), at College of Physician & Surgeon, Pakistan (2008 – to date)

  • Paper Setter for FCPS and MCPS at College of Physicians and Surgeon, Pakistan (2010 – to date)

  • Observer for FCPS Part II practical examination, at College of Physician & Surgeon, Pakistan (2008)

  • Chief Resident, Department of Pathology & Microbiology, AKU (1998-1999)

  • Co-Chief Resident, Department of Pathology & Microbiology, AKU (1997-1997)

  • Member representative Anesthesia, Radiology & Pathology Group (RAP group), PGME committee, AKU (1998-1999)


Examiner/Assessor

  • Assessment of MCPS and FCPS paper II theory exam at CPSP

  • Paper setter for FCPS and MCPS examinations at CPSP (2010–to date)

  • Developed questions based on data interpretation for CPSP question bank (2010–to date)

  • Examiner of practical examination for FCPS part II by CPSP (2010 – to date)


Other Activities

  • Clinical research discussions (2007–to date)

  • Case discussion and interactive lectures for residents of FCPS program (2005 – to date)

  • Supervisor of 4 Chemical Pathology residents for FCPS II (2006 – to date)

  • Revised curriculum for FCPS chemical pathology residency training program for AKU post graduate residency program

  • Organized theory and practical mock exams for FCPS candidates of AKUH

  • Organized FCPS practical exam for CPSP examination at AKUH (as an exam center)


Allied Health Professional
2008 – to date Member Allied Health Task Force Committee, AKU
Teaching and Training – Medical Technologists

1996– to date
  • Teaching of trainee medical technologists in the one-year Clinical Laboratory technologist training program at AKUH

  • Organize Medical Technologist Training teaching of technologists at the section of Chemical Pathology (2000 – to date)


  • Supervise technologist research projects in their presentation and publication of research material

  • Review and supervise manuscript of medical technologist for Departmental newsletter (LABRAD)


Nursing Students

  • Conducted lecture for M.Sc. N students at School of Nursing (2010)


Master’s program in epidemiology and biostatistics

  • Facilitated as an expert in the workshop on non-communicable diseases on “Evaluation of biomarkers used in Oncology: Applicability in research”(2011)

  • Teaching session in Nutrition course on “Research experience on vitamin D in Pakistan” (2009-to date)

  • Participated in the research activities of students,two students have completed their research projects with me.

  • Committee member on research proposal of student (Anna Zulfiqar E11002) of MSc Epi Bio


INNOVATIONS IN EDUCATION
Undergraduate Teaching

  • Designing and development of question bank for Y-II

  • Implementation of table of specification for all examination for paper setting

  • Introduced the concept of “disorder of sexual differentiation” in endocrine and reproduction module (2006)


Post Graduate Teaching

  • Developed end of year objectives for post graduate trainees of Chemical Pathology

  • Revised curriculum for FCPS chemical pathology residency training program at AKU

  • Developed tools of formal assessment and evaluation with record keeping

  • Developed a question bank for Chemical Pathology


Medical Technologist

  • Initiated and submitted the draft concept of developing curriculum for technologist training program at Clinical Laboratory. The initial proposal is made as an assignment for Advanced level course on curriculum development conducted by DED. The assignment has been reviewed by DED. It is being submitted for departmental review.


SERVICE AND ACTIVITIES WITHIN / OUTSIDE OF THE AGA KHAN UNIVERSITY


  1. Innovations in service / processes / procedures, since last promotion




  • Leading the group for sectional activities for College of American Pathologist accreditation. Currently developing and reviewing all process/all procedures and policies and all manuals in the Section for CAP accreditation (2012)

  • Developed a program for point of care testing (POCT) for implementation at the institutional level (2012). Work is in process

  • Developed several screening panels for laboratory testing like bone health and osteoporosis. These testing panels are now very popular and have significant contribution in volume and revenue growth (2011)

  • Team member for Process Improvement in Section of Chemical Pathology by Total Lab Automation

  • Developed “Manual of provocative testing” in Chemical Pathology

  • Developed a tool for methodology evaluation of two tests

  • Working in collaboration with Molecular Pathology for starting of new molecular tests




  1. New services introduced




  • Initiating a clinical laboratory service for diaagnosis of inborn errors of metabolism (Nov. 2012)

  • Initiation of sub-specialty of metabolic bone and mineral diseases from Chemical Pathology platform (2008)

  • Initiated new bone markers in section of chemical pathology like vitamin D, N telopeptide of type I collagen, ionized calcium, tubular indices for phosphate reabsorption. Currently working on other markers (2005-2008)




  1. Service on Committees within and external to the University




  1. University related:

  • Chair of Endocrine and reproduction module (2011– 2012)

  • Member YII Committee (2011 – to date)

  • Member sub-committee of YII for reviewing the content of PBL in YI & II (2011–to date)

  • Member of curriculum committee (2007- 2011)

  • Chair of YII committee (2007 – 2011)

  • Member of YI committee (2005-2007)

  • Interview panel for admission of undergraduates (2010, 2012)

  • Member of search committee for Chair of Pathology & Microbiology (2009)




  1. Department/Section related:

  • Acting section head in absence of section head

  • Member departmental committee on ethics (2012)

  • Member task force for CAP accreditation

  • Co chair question review committee ( 2012-to date)

  • Member departmental sub-committee on appraisal & promotion (2012- to date)

  • Member departmental sub-committee on education (2012-to date)

  • Member departmental sub-committee on research (2011-to date)




  1. Other Administrative Assignments:

  • Interviewed faculty members, lab technologists and residents at AKU (2005 – to date)

  • Working group on College of American Pathologist accreditation at Section

  • Member of group working on integration of molecular testing in different sections of department

  • Editor LABRAD (2005 – to date)

  • Assistant editor LABRAD (2000 – 2005)

  • Publication of laboratory updates (2000 – 2007)



PUBLICATIONS (BASED ON BACHELOR’S MASTER’S OR PH.D. RESEARCH)


    1. Peer reviewed - research papers

  1. R Bhimji,AH Khan*, I Lashari S Sabir, Z Nazir, G Billoo. Profile of children with congenital adrenal hyperplasia-A hospital study. JPMA 2004 Oct;54(10):509-12




  1. M Azim, AH Khan*, Zahida Latif, J. A. Paul, M Khurshid. Chromosomal abnormalities as a cause of recurrent abortions. J P.M.A. Volume 53, No. 3, March 2003, 117-119.




  1. AH Khan*, M I Nasir and T Moatter. Characterization of pathogenic mutations in 21-hydroxylase gene of Pakistani patients with congenital adrenal hyperplasia -A preliminary report. J.P.M.A, Vol. 52, No. 7 7/7 July 2002.




  1. AH Khan*, A Khan, F Ghani, M Khurshid. Low lead exposure and blood lead levels in children: A Cross-sectional survey. Archives of environmental health. Nov/Dec 2001 [Vol. 56 (No. 6), 501-505.




  1. AH Khan*,Z Khilji, M Azim, M Khurshid. Trisomy 9 mosacism: A case report. JPMA, Vol 51, No. 3, March, 2001




  1. AH Khan*, F Ghani, A Khan, A Khan, M Khurshid. Role of serum angiotensin converting enzyme in sarcoidosis. J.P.M.A., Vol. 48, No. 5, May 1998:131-133.




    1. Letters to Editor

  1. AH Khan*. Trisomy 16, cause of first trimester abortion. J.P.M.A, Vol. 51, No. 10, Oct, 2001.378-379


PUBLICATIONS (AS PRINCIPAL or CO-INVESTIGATOR POST-MOST ADVANCED DEGREE)


  1. Peer reviewed - research papers


International

  1. Q Humayun, R Iqbal, I Azam, AR Siddiqui, AH Khan, N Ansari. Development and validation of sunlight exposure measurement questionnaire (SEM-Q) for use in adult population residing in Pakistan. BMC Public Health 2012, 12:421




  1. FJ Dar, R Iqbal, F Ghani, I Siddiqui, AH Khan*. Bone health status of premenopausal healthy adult females in Pakistani females. Archive of Osteoporosis. DOI: 10.1007/s11657-012-0085-0




  1. AH Khan*, D Rohra, S Saghir, S Udani, R Wood, A Jabbar. No change in calcium absorption in adult Pakistani population before and after vitamin D administration using Strontium as surrogate. Osteoporosis International http://dx.doi.org/10.1007/s00198-012-2007-9




  1. L Jafri, AH Khan*, A Hussain, F Ghani, I Siddiqui. Automated reporting of estimated glomerular filtration rate: A comparison of creatinine clearance, modification of diet in renal disease and Cockcroft gault equations from Pakistan. British Journal of Medicine & Medical Research, 1(4): 445-458, 2011




  1. L Jafri, AH Khan*, AA Siddiqui, S Mushtaq, R Iqbal, F Ghani, I Siddiqui. Comparison of high performance liquid chromatography, radioimmunoassay and electro chemiluminescence immunoassay for quantification of serum 25 hydroxy vitamin D. Clin Biochemistry. Jul;44 (10-11):864-8




  1. AH Khan, M Aban, J Raza, N Haq, A Jabbar, T Moatter. Ethnic disparity in 21 hydroxylase gene mutations identified in Pakistan congenital adrenal hyperplasia patient. BMC Endocrine Disorders, 2011, 11:5




  1. A H Khan*, G Naureen, R Iqbal. Determination of bone health status in community dwelling females in Karachi, Pakistan. Osteoporosis Int (2011) 22( Suppl 5):S689-696.




  1. AH Khan*, D Rohra, S Saghir, S Udani, R Wood, A Jabbar. Response of a single ‘mega intramuscular dose’ of vitamin D on serum 25OHD and parathyroid hormone levels in vitamin D deficient volunteers in Karachi Pakistan. Osteoporosis Int (2011) 22( Suppl 5):S697-751.




  1. R Iqbal, L Jafri, A Haroon, AH Khan*. Is neighborhood level information associated with serum vitamin D levels in individuals residing in Karachi, Pakistan? Osteoporosis Int (2011) 22( Suppl 5):S697-751.




  1. SK Udani, AH Khan, SA Qureshi, S Khan, F Ghani, N Kayani. Evaluation of bone metabolism in breast cancer patients and its correlation with serum vitamin D levels. Osteoporosis Int (2011) 22( Suppl 5):S697-751




  1. S Mansoor, AH Khan, F Ghani, Z Fatimi, S Badruddin, S Mansoor, I Siddiqui, A Jabbar. Prevalence and significance of Vitamin D deficiency and insufficiency among apparently healthy adults. Clinical Biochemistry (2010); 4(18):1431-5.




  1. D Saleheen, A Nazir, S Khanum, S R. Haider, Usman Ahmad, H Khalid, I Hussain, K Shahid, AH Khan,PMFrossard. A Novel Haplotype in ABCA1 Gene Effects Plasma HDL-C Concentration. Int J Cardiol. 2007 Jan 31; 115(1):7-13.




  1. A Jabbar, Farooqi A, AH Khan, N Islam, Haque, J Akhter. Clinical Characteristics and outcome of Diabetic Ketoacidosis in Pakistani adults with Type 2 Diabetes Mellitus. Diabetic Medicine; 21, 920-923, 2004


In Press:


  1. AH Khan, R Iqbal, G Naureen, F Nasir, F Dar. Prevalence of vitamin D deficiency and its correlates: Results of a community based study conducted in Karachi, Pakistan. Archive of Osteoporosis




  1. AH Khan, G Naureen, R Iqbal. High prevalence of obesity call for a priority action for non-communicable disease crises  in adult women: findings of a community based study in Karachi, Pakistan. Submitted to Food & Nutrition Bulletin. August 2012


National

  1. AH Khan, L Jafri, MA Hussain, S Ishaq. Diagnostic utility of anti-citrullinated protein antibody and its comparison with rheumatoid factor in rheumatoid arthiritis. JCPSP 2012, Vol 22(11)




  1. AH Khan*, D Rohra, S Saghir, S Udani, R Wood, A Jabbar. Response of a single mega intramuscular dose of vitamin D on serum 25OHD and parathyroid hormone levels in volunteers in Karachi, Pakistan. JCPSP 2012, Vol 22 (4):207-212




  1. FJ Dar, AH Khan*, I Siddiqui, F Ghani. Pattern of drug of Abuse in chemical samples. JCPSP 2010, Vol 20 (9): 608-611




  1. R Iqbal, AH Khan*. Possible causes of vitamin D deficiency in Pakistani population residing in Pakistan. JPMA. Vol. 60, No. 1, January 2010




  1. AH Khan*, NU Haq, J Raza, A Jabbar, T Moatter. Classic virilizing congenital adrenal hyperplasia presenting late: case series from Pakistan. JPMA: Vol. 59 No. 9, September 2009, 643-646.




  1. L Jafri, R Iqbal, AH Khan*. Correlation study of vitamin D levels between reference method (RIA) and the test method (chemiluminescence). JPMA, volume 60 No. 2 Supplement April, 2009 S-01 – S-49.




  1. L Zuberi, AH Khan, Abdul J. Vitamin D deficiency in ambulatory patients. JPMA: Vol 58 No.9: September 2008, 482 – 484.




  1. AH Khan*, A Jabbar, N U Haq, R Sutton. Vitamin D deficiency osteomalacia: The continuing challenge. JCPSP 2008, Vol 18(10): 664-666 (letter).




  1. AH Khan*, A Jabbar, R Baig, NU Haq, R Sutton. Vitamin D deficiency osteomalacia: The continuing challenge. Pak J Pathol 2008; 19 (4): 146 -148




  1. AH Khan*, I Azam, I Siddiqui, N Kayani, M Khurshid. Work flow analysis: Audit of the turnaround time in clinical chemistry in a tertiary care hospital. Pak Journal of Pathology 2008; 19(3): 89-92.


Submitted:

  1. I Saher, AH Khan*. Frequency and distribution of congenital adrenal hyperplasia among different provinces of Pakistan. Submitted to JCPSP in March 2012




  1. R Iqbal, H Ali, F Dar, M Bilgirami, G Bano, AH Khan. Validation of a food frequency questionnaire (FFQ) for assessing macronutrient and calcium intake in adult, Pakistani population. Submitted to JCPSP December 2011




  1. R Iqbal, L Jafri, A Haroon, AH Khan*. Illuminating the dark side: Vitamin D status in ten different localities of Karachi, Pakistan. Submitted to JCPSP September 2011




  1. Letters to Editor 




  1. AH Khan*, L Jafri. Ionized calcium cannot predict vitamin D deficiency. Ind J Clin Biochem. (Oct-Dec 2011) 26(4): 428-429




  1. AH Khan*. Treating vitamin D deficiency (VDD) can also play a role in fight against chronic disease. JPMA Vol 60 No. 2, February 2010




  1. AH Khan*, R Iqbal. Vitamin D deficiency in an ample sunlight country. JCPSP 2009, Vol. 19 (5): 267-268 (editorial)




  1. AH Khan*. Vitamin D deficiency: Are we still ignoring the evidence. JPMA: Vol 58 No.9: September 2008, 482 – 484 (letter).




  1. Book co-authored

Farhan Dar and Aysha Habib Khan. Assessment of bone turnover in adult females and its association with vitamin D blood levels.LAP Lambert Academic Publishing
ISBN 978-3-8473-1686-2, paperback, 184 Pages





  1. Book Chapter authored

Aysha Habib Khan. Chapter 24: Nephrolithiasis and interrelationship of vitamin D, Parathyroid hormone and Calcium-An update. Urolithiasis: Basic Science and Clinical Practice. Editors J.J. Talati; H.G. Tiselius; D.M. Albala; Z.YE. Tongji. Springer 2013


  1. List of abstracts and presentations since last promotion only

  1. AH Khan, G Naureen, FJ Dar, R Iqbal. Determination of Bone Health Status with Vitamin D Deficiency (VDD) in Community Dwelling Females in Karachi, Pakistan. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. M Riaz, H Majid, AH Khan. Frequency of Secondary Hyperparathyroidism in Subjects with Vitamin D Deficiency. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. L Jafri, S Ishaq, A Hussain and AH Khan. Diagnostic Utility of Anti–Citrullinated Protein Antibody in Rheumatoid Arthritis and its Comparison with Rheumatoid Factor in Patients from a Tertiary Care Hospital of Pakistan. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. N Sherazi, R Iqbal, AH Khan. Relationship of Fibroblast Growth Factor 23 Levels with Dietary Phosphate Intake and Fractional Excretion of Phosphate (FEPO4) in Healthy Volunteers. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. H Majid, AH Khan, T Moatter. R990G Polymorphism of Calcium Sensing Receptor (CaSR) Gene is Associated with Parathyroid Hormone and Calcium Levels in Subjects with Vitamin D Deficiency. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. M Q Masood, G Naureen, AH Khan. Efficacy of Commercially Available Mega Doses of Vitamin D3 to Achieve Optimum Vitamin D Levels: Preliminary Findings from Pakistan. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. R Iqbal, F J Dar, M Bilgrami, G Bano, AH Khan. Validation of a Food Frequency Questionnaire for Assessing Macronutrient and Calcium Intake in Adult Population Residing in Karachi. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. R Iqbal, G Naureen, AH Khan. High Prevalence of Osteopenia and Osteoporosis in an Apparently Healthy, Adult Pakistani Population Residing in a Rural Community. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. ST Naeem, AH Khan, I Siddiqui, F Ghani. Frequency of Parathyroid Hormone Disorders in Patients Presenting at an Out-patient Clinic. Department of Pathology and Microbiology/Clinical Laboratories Research Day; October 11, 2012




  1. R Maher, L Jafri, AH Khan. A comparison of vitamin D status in critically ill patients and apparently healthy individuals at the 35th Annual & 5th International Conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. H Majid, AH Khan, Q Masood, F Ghani, I Siddiqui. Role of ‘Homeostatic Model Assessment-Insulin Resistance’ in assessing insulin resistance in polycystic ovarian syndrome. at the 35th Annual & 5th International Conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. G Naureen, AH Khan, F Dar, R Iqbal. Determination of bone health status in community dwelling female in Karachi, Pakistan at 35th annual and 5thinternational conference of Pakistan Association of Pathologist meeting at CPSP, December 2011. Awarded best oral presentation




  1. S Iqbal, F Ghani, R Qureshi, AH Khan, I Siddiqui, I Azam. Presence of thyroid peroxidase antibody among apparently euthyroidpregnant women and risk of adverse pregnancy outcomes at the 35th Annual & 5th International Conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. L Jafri, K Waqar, S Hira, T Javed, AH Khan,I Siddiqui,F Ghani. Utility of  B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) in chronic kidney disease: a head to head comparison of two heart failure markers. (Awarded “Best Oral Presentation” for 2011) at the 35thannual & 5thinternational conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. S Iqbal, AH Khan, F Ghani, I Siddiqui. Frequency and distribution of congenital adrenal hyperplasia in different regions of Pakistan. at the 35thannual & 5thinternational conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. ST Naeem, AH Khan, I Siddiqui, F Ghani. Frequency of parathyroid hormone disorders in patients presenting in medical clinic patients. at the 35th Annual & 5th International Conference of Pakistan Association of Pathologist (PAP) 2011, CPSP, Karachi




  1. AH Khan, G Naureen, R Iqbal. Determination of bone health status in community dwelling female in Karachi, Pakistan. IOF Regionals – 1st Middle East & Africa Osteoporosis Meeting in Dubai (October 19-22, 2011) (IOF Young Investigator Award)




  1. R Iqbal, L Jafri, A Haroon, AH Khan*. Is neighborhood level information associated with serum vitamin D levels in individuals residing in Karachi, Pakistan? IOF Regionals – 1st Middle East & Africa Osteoporosis Meeting in Dubai (October 19-22, 2011)




  1. S K Udani, AH Khan, SA Qureshi, S Khan, F Ghani, N Kayani. Evaluation of bone metabolism in breast cancer patients and its correlation with serum levels of vitamin D (25OHD).IOF Regionals – 1st Middle East & Africa Osteoporosis Meeting in Dubai (October 19-22, 2011)




  1. AH Khan, D Rohra, S Saghir, S Udani, R Wood, A Jabbar. Response of a single ‘mega intramuscular dose’ of vitamin D on serum 25OHD and parathyroid hormone levels in vitamin D deficient volunteers in Karachi, Pakistan. IOF Regionals – 1st Middle East & Africa Osteoporosis Meeting in Dubai (October 19-22, 2011)




  1. AH Khan, F Dar, R Iqbal, F Ghani, I Siddiqui. Assessing bone health in adult premenopausal females in Karachi–A preliminary report from Pakistan. 4thnational conference of Pakistan Society of Chemical Pathologist (PSCP), Lahore, February 2011




  1. L Jafri, AH Khan, I Siddiqui, F Ghani. Is reflex reporting of estimated glomerular filtration rate premature? 4th national conference of Pakistan Society of Chemical Pathologist (PSCP), Lahore, February 2011




  1. L Jafri, AH Khan, MA Hussain, F Ghani, I Siddiqui, S Ishaq. Diagnostic accuracy of rheumatoid factor and anti–citrullinated protein antibody in rheumatoid arthritis. 4thnational conference of Pakistan Society of Chemical Pathologist (PSCP), Lahore, February 2011




  1. F Ghani, N Sherazi, I Siddiqui, AH Khan. Assessing frequency of food and environmental allergens in patients having high total IgE levels. 4thnational conference of Pakistan Society of Chemical Pathologist (PSCP), Lahore, February 2011




  1. N Sherazi, AH Khan,I Siddiqui, F Ghani. Fibroblast growth factor 23 (FGF-23) levels in healthy volunteers and its relationship with serum phosphate and tubular maximum for phosphate reabsorption (TmP/GFR). 4thnational conference of Pakistan Society of Chemical Pathologist (PSCP), Lahore, February 2011




  1. R Iqbal, G Bano, M Bilgirami, F Dar, AH Khan*. Development and validation of a food frequency questionnaire for assessing macronutrient and calcium in women residing in Karachi. Poster presented at the ASBMR 2010 Annual meeting 15-19, at Metro Convention Center, Toronto, Ontario, Canada




  1. AH Khan, F Dar, R Iqbal, I Siddiqui, F Ghani. Assessing bone health in adult premenopausal females in Karachi-A preliminary report from Pakistan. Poster presented at the ASBMR 2010 annual meeting 15-19, at Metro Convention Center, Toronto, Ontario, Canada




  1. F Dar, AH Khan, R Iqbal, I Siddiqui, F Ghani. Assessment of bone turnover and its association with vitamin D blood levels in adult female residing in Karachi.

  1. Accepted for poster presentation in Focus 2009. The Association of Clinical Biochemistry annual national meeting at Liverpool

  2. Oral presentation at PAP Meeting at Abbottabad, 2008




  1. L Jafri, AH Khan, R Iqbal, I Siddiqui, F Ghani. Correlation study of Vitamin D levels between reference method (RIA) and test method (Chemiluminescence)

  1. Oral presentation at PGME conference 2009, at AKU

  2. Oral presentation at PAP meeting at Abbottabad, 2008.




  1. R Iqbal, M Bilgirami, AH Khan, S Urooj, A Jabbar and D Rohra. Developing a food frequency questionnaire for assessing dietary calcium intake in an adult population, presented at Research Assembly 2008 at The Aga Khan University, Karachi, Pakistan.




  1. S Mansoor, F Ghani, I Siddiqui, AH Khan. Determinants of serum {25(OH)D} status in otherwise healthy females and males at PAP meeting at Abbottabad, 2008




  1. S Iqbal, F Ghani, R Qureshi*, AH Khan, I Siddiqui. Frequency of thyroid peroxidase antibody in pregnant women” poster presentation. Abstract presented at the 32th National conference of Pakistan Association of Pathologist (PAP), Abbottabad, November 2008




  1. S Mansoor, F Ghani,AH Khan, I Siddiqui. Determinants of serum 25(OH)D status in otherwise healthy females and males. Abstract presented at the 32thnational conference of Pakistan Association of Pathologist (PAP), Abbottabad, November 2008




  1. S Kanwal, F Ghani,AH Khan, I Siddiqui. Chemical composition of renal stone and its relationship with age, sex and weight of the renal stones evaluated from 1999 to 2006 at referral laboratory. Abstract presented at the 31stnational conference of Pakistan Association of Pathologist (PAP) 2007, Peshawar




  1. S Mansoor, F Ghani, AH Khan, I Siddiqui. Prenatal diagnosis of downs syndrome by karyotyping through amniocentesis in triple screen positive cases. Abstract presented at the 31stnational conference of Pakistan Association of Pathologist (PAP) 2007, Peshawar




  1. R UL Hassan, AH Khan, M Aban, N UL Haq, J Raza, A Jabbar, T Moatter. Classic virilizing congenital adrenal hyperplasia presenting late: Case series from Pakistan

  1. Poster presentation at 2ndbiennial conference of Pakistan Society of Chemical Pathologists, March 2007

  2. Poster presentation at symposium of Baqai Medical College, Feb 2007




  1. AH Khan, M Aban, R UL Hassan N UL Haq, J Raza, A Jabbar, T Moatter. Mixed array of mutations identified in 21 hydroxylase gene of patients with congenital adrenal hyperplasia.

  1. Association of Clinical Pathologist national scientific meeting 14th -15th June 2007, Church House, Westminster

  2. Oral Presentation in 2ndbiennial conference of Pakistan Society of Chemical Pathologist, AKU Karachi (Awarded Azhar gold medal for best paper presentation)

  3. Symposium of Baqai Medical College held at Baqai University, Karachi

  4. Poster presentation in Pakistan Association of Pathologists meeting at Lahore 2006

  5. 1stmultidisciplinary conference on human resource capacity building, East Africa, 4th -6th Sept




  1. S Mansoor, AH Khan, F Ghani, Z Fatimi, S Badruddin, S Mansoor, I Siddiqui, A Jabbar. Vitamin D status among healthy adults- a preliminary report from Pakistan.

  1. Association of Clinical Pathologist national scientific meeting 14th -15th June 2007, Church House, Westminster

  2. The Bone & Kidney, Oct. 12-15 2006, Copenhagen, Denmark.

  3. Pakistan Association of Pathologist meeting at Lahore 2006




  1. J Jabbar, I Siddiqui, F Ghani, F Riaz, AH Khan. Insulin tolerance test: cost benefitsanalysis. Abstract presented at the 30thnational conference of Pakistan Association of Pathologist (PAP), Lahore, November 2006




  1. AH Khan, M Aban, R UL Hassan N UL Haq, J Raza, A Jabbar, T Moatter. Genotype phenotype correlation of patients with congenital adrenal hyperplasia and identification of mutations in their 21 hydroxylase gene. (On behalf of the group). Research seminar on reproductive health. Friday, September 15, 2006




  1. LM Zuberi, AH Khan, S Arshad, M Islam and A Jabbar. Vitamin D deficiency in medical clinic patients. Poster presentation in AKU research assembly on March 7- 8, 2006




  1. AH Khan, S Mushtaq, Z Naqvi, A Siddiqui. High performance liquid chromatographic method for determination of 25OHD. Departments of Pathology, Research Lab, Biological and Biomedical Science, Aga Khan University. Poster presentation in AKU research assembly on March 7- 8, 2006




  1. Others


Dissertation for FCPS

  1. Aysha Habib Khan, Naila Kayani. Blood lead levels in children (1997)




  1. Farhan J Dar, Aysha Habib Khan. Assessment of bone turnover in healthy adult females and its association with vitamin D blood levels(2010)




  1. Noreen Shirazi, Aysha Habib Khan. Fibroblast growth factor 23 levels in healthy volunteers and correlation with serum phosphate and tubular maximum for phosphate reabsorption (2012)


Newspaper/Newsletter articles

  1. Report on 4th biennial course in Chemical Pathology for newsletter of International Federation of Clinical Biochemistry (IFCC), 2012

  2. Prevalence and causes of vitamin D deficiency in south Asian population residing in different geographical areas. Dr Aysha Habib Khan, Ghazala Naureen, Dr. Romaina Iqbal. APFCB newsletter (2012)

  3. Report on Pakistan Society of Chemical Pathologist APFCB newsletter 2011

  4. Bone health for life. Women’s Own, April 2011

  5. Growing interest in assessing vitamin D status and issues of vitamin D testing: Experience from Pakistan. Newsletter of Asian Pacific Federation of Clinical Chemistry. 2010

  6. Assessment of osteoporosis risk by NTx – A biochemical marker. LABRAD, January 2010

  7. N-telopeptide of type I collagen: A biochemical tool for assessing bone turnover. LABRAD, January 2009

  8. Vitamin D deficiency: Are we still ignoring the evidence. LABRAD, September 2008

  9. Vitamin D measurement. LABRAD, September 2007.

  10. Lab diagnosis of metabolic bone diseases. LABRAD, May 2007

  11. Overseas development award. ACP National Scientific Meeting 14th -15th June 2007, Church House, Westminster and attachment at Kings College Hospital, London 12th June -18th July, Aysha Habib Khan. Association of Clinical Pathologist newsletter, UK September issue 2007

  12. What causes Vitamin D deficiency? Physician Newsletter, AKUH

  13. Vitamin D deficiency. Gulf Today, December 2006

  14. The battle to conquer osteomalacia. DAWN, Health Page, 11th Dec 2002

  15. CAH: defeating myths and dogmas. DAWN, Health Page, 10th July 2002


Editorial Activities- Reviewer and/or evaluator
Reviewer of Journal Articles:

Journal of Pakistan Medical Association



Annals of Karachi Medical & Dental College

Reviewer of Grant Proposals:

  • Higher Education Commission (HEC), Pakistan

  • University Research Council of Aga Khan University, Karachi Pakistan


Editorial Activities Related To Newsletter

  1. Representative of the working group on newsletter of International federation of clinical chemistry (IFCC)from Asia-Pacific Federation of Clinical Biochemistry and Laboratory Medicine (2011-To date)

  2. Member editorial team Asia-Pacific Federation of Clinical Biochemistry and Laboratory Medicine(APFCB) newsletter (2009-To date)

  3. Editor LABRAD: Quarterly publication of the Departments of Pathology & Radiology and Clinical laboratories AKUH (Jan 2005 – to date)

  4. Assistant Editor LABRAD (2000 -2004)

  5. Responsible for the publication of laboratory updates, for providing information about tests/procedure to the physicians all over Pakistan since 2000 on new & old tests in hematology, histopathology, microbiology, molecular pathology &chemical pathology.


GRANTS
Intramural funding streams:
URC:

  1. Evaluation of bone health in Pakistani children with beta thalassemia major. Co-PI, URC 2012.Rs 17,00,000 only

  2. Efficacy of 25 (OH) vitamin D supplementation and physical activity in improving musculoskeletal health in individuals with chronic kidney disease (CKD). Investigator, URC 2012 $22857 only. Work in progress

  3. Determination of effective vitamin D replacement and monitoring strategies in vitamin D deficient state (EVIREST). Co-PI, Seed Grant from URC 2011. PKR 9,23,863,Work in progress

Grants closed & publications achieved

  1. To assess the effect of dietary calcium intake and vitamin D status on bone turnover markers in Pakistani adult females. PI, Awarded from Pakistan Science Foundation in May 2010– December 2011, Rs 19, 844, 16 only

  2. Determination of calcium absorption from intestine at various Vitamin D levels using strontium as the surrogate marker. PI, Awarded from HEC in June 2009-Nov 2010, Rs 821,100 only

  3. Genotype phenotype correlation and characterization of mutation in 21-hydroxylase gene in patients with Congenital Adrenal Hyperplasia. PI, URC 2003-2007,US$ 15,000.



GRADUATE STUDENTS SUPERVISED
For Fellowship Projects


  1. Hafsa Majid; 2010 – todate (Primary Supervisor); Polymorphism of CaSR gene and its association in subjects with vitamin D deficiency. US $ 1000. 2011 resident seed grant from Department of Pathology & Microbiology. Ongoing




  1. Talha Naeem; 2009 – todate (primary Supervisor); To determine the validity of bone turnover markers in patients with osteoporosis and osteopenia presenting at a metabolic bone clinic. US $ 1000. 2010 resident seed grant from Department of Pathology & Microbiology. Ongoing




  1. Noreen Shirazi; 2008-2012 (primary supervisor);. Fibroblast growth factor 23 levels in healthy volunteers and correlation with serum phosphate and tubular maximum for phosphate reabsorption. US $ 1050. 2009 resident seed grant from Department of Pathology & Microbiology. Ongoing. Completed




  1. Farhan Dar; 2007 – 2010 (primary Supervisor); Assessment of bone turnover and its association with vitamin D blood levels in adult females.US$ 1000 from resident seed grant, 2007 from Department of Pathology & Microbiology,US$ 3000 from URC of Aga Khan University. Completed




  1. Shireen Mansoor; (2005-2007) (secondary supervisor). Vitamin D status in a population of healthy adults-A pilot study. URC US$ 3000 from Aga Khan University. Completed


For Masters Projects
Anna Zulfiqar (E11002); 2010 todate; (Committee member) Association of dental caries with passive smoking in 3-11 years old children of Karachi, Pakistan. Ongoing


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