Appendix 2-5: Rejected ecotox bibliography for Chlorpyrifos

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Environment concentrations of 16 pollutants were collected from published documents. Then the risk ratios (PEC/PNEC ratio) of these 16 pollutants were calculated and arranged. Among the 16 pollutants, anthracene, phenanthrene, naphthalene, fluoranthene, atrazine and malathion are likely to pose ecological risk to the environment of Liangmei Bay and Tianmu Lake in Taihu Lake, and Wuli Lake. Moreover, chlorpyrifos, tributyltin oxide and tricyclohexylhydroxytin have great potential of causing ecological risk, though no concentration data were reported.
Keywords: Risk assessment
Keywords: Anthracene
Keywords: Aquatic organisms
Keywords: Microbiology Abstracts C: Algology, Mycology & Protozoology; Ecology Abstracts; Aqualine Abstracts; Water Resources Abstracts; Pollution Abstracts; Risk Abstracts; Environment Abstracts
Keywords: SW 3040:Wastewater treatment processes
Keywords: Degradation
Keywords: ENA 12:Oceans & Estuaries
Keywords: Malathion
Keywords: Models
Keywords: Lakes
Keywords: tributyltin oxide
Keywords: K 03330:Biochemistry
Keywords: Assessments
Keywords: Pollutants
Keywords: Chronic toxicity
Keywords: China, People's Rep., Tai Hu L.
Keywords: R2 23050:Environment
Keywords: D 04060:Management and Conservation
Keywords: Algae
Keywords: AQ 00001:Water Resources and Supplies
Keywords: Sensitivity
Keywords: Fluoranthene
Keywords: Data processing
Keywords: Naphthalene
Keywords: Toxicity
Keywords: Aquatic ecosystems
Keywords: Ecological Distribution
Keywords: Sediments
Keywords: Model Studies
Keywords: Chlorpyrifos
Keywords: Risk
Keywords: Phenanthrene
Keywords: Prevention
Keywords: Water Pollution Effects
Keywords: Atrazine
Keywords: China, People's Rep., Jiangsu Prov., Wuli L.
Date revised - 2012-05-01
Language of summary - English
Location - China, People's Rep., Tai Hu L.; China, People's Rep., Jiangsu Prov., Wuli L.
Pages - 301-306
ProQuest ID - 1014106539
SubjectsTermNotLitGenreText - Risk assessment; Anthracene; Aquatic organisms; Fluoranthene; Data processing; Naphthalene; Aquatic ecosystems; Malathion; Sediments; Models; Chlorpyrifos; tributyltin oxide; Lakes; Phenanthrene; Pollutants; Chronic toxicity; Atrazine; Algae; Sensitivity; Prevention; Degradation; Toxicity; Risk; Assessments; Water Pollution Effects; Ecological Distribution; Model Studies; China, People's Rep., Tai Hu L.; China, People's Rep., Jiangsu Prov., Wuli L.
Last updated - 2012-12-03
British nursing index edition - Environmental Chemistry - Huanjing Huaxue. Vol. 31, no. 3, pp. 301-306. Mar 2012.
Corporate institution author - Jiang, D; Yue, L; Zhu, Y; Yin, D
DOI - MD-0018706668; 16671733; 0254-6108 English

628. Jiao, L. F.; Yan, C. H.; Zhao, J.; Jia, L.; He, J., and Peng, S. Q. Reproductive Toxicity of Low-Level Chlorpyrifos Repeated Exposure and Its Mechanisms in Male Rats. Research and Evaluation Center for Toxicology, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China,//: 2011; 25, (6): 568-575(CHI) (ENG ABS).

Rec #: 2500
Call Number: NON-ENGLISH (CPY)
Notes: Chemical of Concern: CPY

629. Jimenez, J. J.; Bernal, J. L.; del Nozal, M. J.; Bernal, J., and Toribio, L. Persistence and degradation of metalaxyl, lindane, fenvalerate and deltamethrin during the wine making process. 2007; 104, (1): 216-223.

Rec #: 62189
Keywords: FOOD
Notes: Chemical of Concern: CPY
Abstract: Abstract: The persistence and degradation of four acaricides (metalaxyl, lindane, fenvalerate and deltamethrin), used to control pests in vineyards, in experimental must and wine samples, have been studied. Commercial formulations of the pesticides were added to non-settled must and their fate during a common vinification method for white and red wines was investigated. Analytes in the extracts were determined by GC/EIMS after a solid-phase extraction on polymeric cartridges to isolate them from the must and wine samples. It was verified that white wines generally contained higher amounts of residues. Moreover, some degradation products, not reported until now, have been observed in the samples in addition to some compounds - byproducts from the manufacturing and excipients - initially present in the commercial formulations. (c) 2006 Elsevier Ltd. All rights reserved.
Keywords: pesticides, impurities, degradation products, wine, fate
ISI Document Delivery No.: 169ZL

630. Jin, B-H; Xiao, F; Chen, B; Chen, P-J; Xie, L-Q, and Jin, B-H. Simultaneous Determination of 42 Organic Chemicals in Bottled Water by Combining C18 Extraction Disk With Gc-Ms and Lc/Ms/Ms Technique. 2010 Mar; 8, (1): 116-125.

Rec #: 48059
Keywords: FOOD
Notes: Chemical of Concern: CPY
Abstract: Abstract: A method for the determination of 42 hazard residues required by 'Japan Positive List System' in bottled water was described. Hazard compounds in bottled water were extracted with a solid phase extraction step using C18 disks. Determination was carried out by gas chromatography/mass spectrometry (GC/MS) and liquid chromatography-tandem mass spectrometry (LC/MS/MS). The disk extraction has high throughput which is well adapted to isolate and enrich these compounds from large volumes of water. For the water sample spiked at three concentration levels (LOQ, 4 times LOQ and 8 times LOQ), the recoveries of all analytes ranged between 65% and 120% with a relative standard deviation < 24% (n = 8).
Keywords: Chemicals
Keywords: Bottled water
Keywords: Pollution Abstracts; Environment Abstracts; Water Resources Abstracts; Aqualine Abstracts
Keywords: Residues
Keywords: Water sampling
Keywords: Gas chromatography
Keywords: Water wells
Keywords: Mass spectrometry
Keywords: Drinking water
Keywords: Japan
Keywords: Public Health And Safety
Date revised - 2011-02-01
Language of summary - English
Location - Japan
Pages - 116-125
ProQuest ID - 809065245
SubjectsTermNotLitGenreText - Japan; Bottled water; Drinking water; Mass spectrometry; Residues; Water sampling; Water wells; Gas chromatography; Chemicals
Last updated - 2011-11-09
Corporate institution author - Jin, B-H; Xiao, F; Chen, B; Chen, P-J; Xie, L-Q
DOI - OB-MD-0012925361; 12536992; 1477-8920 English

631. Jin, H.; Oyoshi, M. K.; Le, Y.; Bianchi, T.; Koduru, S.; Mathias, C. B.; Kumar, L.; Le Bras, S.; Young, D.; Collins, M.; Grusby, M. J.; Wenzel, J.; Bieber, T.; Boes, M.; Silberstein, L. E.; Oettgen, H. C., and Geha, R. S. Il-21r Is Essential for Epicutaneous Sensitization and Allergic Skin Inflammation in Humans and Mice.

Rec #: 50969
Notes: Chemical of Concern: CPY
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ABSTRACT: Atopic dermatitis (AD) is a common allergic inflammatory skin disease caused by a combination of intense pruritus, scratching, and epicutaneous (e.c.) sensitization with allergens. To explore the roles of IL-21 and IL-21 receptor (IL-21R) in AD, we examined skin lesions from patients with AD and used a mouse model of allergic skin inflammation. IL-21 and IL-21R expression was upregulated in acute skin lesions of AD patients and in mouse skin subjected to tape stripping, a surrogate for scratching. The importance of this finding was highlighted by the fact that both Il21r-/- mice and WT mice treated with soluble IL-21R-IgG2aFc fusion protein failed to develop skin inflammation after e.c. sensitization of tape-stripped skin. Adoptively transferred OVA-specific WT CD4+ T cells accumulated poorly in draining LNs (DLNs) of e.c. sensitized Il21r-/- mice. This was likely caused by both DC-intrinsic and nonintrinsic effects, because trafficking of skin DCs to DLNs was defective in Il21r-/- mice and, to a lesser extent, in WT mice reconstituted with Il21r-/- BM. More insight into this defect was provided by the observation that skin DCs from tape-stripped WT mice, but not Il21r-/- mice, upregulated CCR7 and migrated toward CCR7 ligands. Treatment of epidermal and dermal cells with IL-21 activated MMP2, which has been implicated in trafficking of skin DCs. These results suggest an important role for IL-21R in the mobilization of skin DCs to DLNs and the subsequent allergic response to e.c. introduced antigen.
MESH HEADINGS: Adoptive Transfer
MESH HEADINGS: Cells, Cultured
MESH HEADINGS: *Dermatitis, Atopic/immunology/pathology
MESH HEADINGS: Disease Models, Animal
MESH HEADINGS: Enzyme Activation
MESH HEADINGS: *Immunization
MESH HEADINGS: Inflammation/chemically induced/*immunology/pathology
MESH HEADINGS: Interleukins/genetics/immunology
MESH HEADINGS: Matrix Metalloproteinase 2/genetics/metabolism
MESH HEADINGS: Mice, Knockout
MESH HEADINGS: Ovalbumin/immunology/pharmacology
MESH HEADINGS: Receptors, CCR7/genetics/immunology
MESH HEADINGS: Receptors, Interleukin-21/genetics/*immunology
MESH HEADINGS: Recombinant Fusion Proteins/genetics/immunology
MESH HEADINGS: *Skin/immunology/pathology
MESH HEADINGS: Spleen/cytology/immunology eng

632. Jin, Qiang Shao and Li, Shao Nan. Dissipation of Chlorpyrifos and Bifenthr in Soil and Their Period of Validity for Termite Control. 2008.

Rec #: 51879
Keywords: FATE
Notes: Chemical of Concern: CPY
Abstract: Abstract: Termite is a group of socialized insect pest that causes serious damage in area south of the Yangtze River in China. Termite control nowadays relys largely on chemical insecticides. Both chlorpyrifos and bifenthrin belong to insecticide candidates recommended by Chinese Association of Property Management for prevention of termite infestation in frames. Chlorpyrifos is the most widely used one in China among the 6 recommended insecticides, and bifenthrin has also been widely applied in recent years. In present study biological activity of chlorpyrifos and bifenthrin to a subground termite, Reticulitermes flaviceps, were assessed by topical application and by soil penetration test. Five cities within area of termite infestation in south of the Yangtze River, i.e., Wuhan, Hefei, Hangzhou Quanzhou, and Chengdu, were selected to performed the field trails. Parallel dissipation studies were conducted in laboratory with soil collected from the 5 trial sites. One of the aims of present studies is to help managers in terms of selecteion of insecticides for termite prevention. Meanwhile the present studies intend to lay a scientific foundation for establishment of criteria for evaluating of chemical barrier for termite prevention, especially the criteria for evaluating of validity period of insecticides in barriers. . The biological testing with Reticulitermes flaviceps indicated that, as the topical application method was used, LC50 was 0.34 mg/L for chlorpyrifos, and the value was 2.32 mg/L for bifenthrin. The soil penetration test conducted with the same species indicated that for chlorpyrifos, 4 mg/kg can be regard as critical concentration that determind whether or not the termite could drill through the 5cm length barriers spiked with chlorpyrifos and and bifenthrin. The soil penetration test also indicated that the minimum lethal concentration for chlorpyrifos was 12 mg/kg, and the value was 16 mg/kg for bifenthrin. This suggested that both chlorpyrifos and bifenthrin held contact toxicity and repellent effect towards termites in field situation, and the repellent effect seemed more outstanding for bifenthrin. The indoor dissipation studies indicated that half lifes of chorpyrifos connecting the 5 soils were in range of 41.3d to 51.9d. In outdoor dissipation studies the half lifes of chorpyrifos were in range of 35.2d to 66.6d. As for bifenthrin the half lifes were in range of 22.1d to 35.9d in indoor studies, whereas in outdoor studies they were in range of 65.8d to 152.3d. Based on data from bioassays the period of validity of chlorpyrifos in terms of termite prevention fell in range of 167~309d, with the longest period in Chengdu and the shortest one in Wuhan. As for bifenthrin the period of validity was in range of 49 to 222, with the longest period in Quanzhou and the shortest one in Wuhan. Groundwater contamination by chlorpyrifos and bifenthrin was monitored along with the soil dissipation study conducted in Hangzhou. Residue of both the 2 insecticides was detected in water samples collected 30cm beneath the top soil, and the levels were detected to be 0.01 mg/L and above. According to previously published toxicity data, the residue concentration of chlorpyrifos and bifenthrin in leachate exceeded limit of tolarence of many aquqtic species which belongs to zooplankton, crustacean, aquatic insect, fish, and so on. It is reasonable to expect, therefore, that if interchange exists between surface water and groundwater at site where the termite-prevention inasecticides are applied, aquatic communites might be obviously impacted.
Keywords: 0285:Agronomy
Keywords: Biological sciences
Keywords: (UMI)AAIH433121
0285: Agronomy
Jin, Qiang Shao
Copyright ProQuest, UMI Dissertations Publishing 2008
Biological sciences
(UMI)AAIH433121 ZH

633. Jin, Yan; Hein, Misty J; Deddens, James a; Hines, Cynthia J, and Jin, Yan. Analysis of Lognormally Distributed Exposure Data With Repeated Measures and Values Below the Limit of Detection Using Sas. 2011 Jan; 55, (1): 97-112.

Rec #: 43589
Notes: Chemical of Concern: CPY
Abstract: Abstract: Studies of determinants of occupational exposure frequently involve left-censored lognormally distributed data, often with repeated measures. Left censoring occurs when observations are below the analytical limit of detection (LOD); repeated measures data results from taking multiple measurements on the same worker. A common method of dealing with this type of data has been to substitute a value (such as LOD/2) for the censored data followed by statistical analysis using the 'usual' methods. Recently, maximum likelihood estimation (MLE) methods have been employed to reduce bias associated with the substitution method. We compared substitution and MLE methods using simulated lognormally distributed exposure data subjected to varying amounts of censoring using two procedures available in SAS: LIFEREG and NLMIXED. In these simulations, the MLE method resulted in less bias and performed well even for censoring up to 80%, whereas the substitution method resulted in considerable bias. We illustrate the NLMIXED procedure using a dataset of chlorpyrifos air measurements collected from termiticide applicators on consecutive days over a 5-day workweek. We provide sample SAS code for several situations including one and two groups, with and without repeated measures, random slopes, and nested random effects.
Keywords: Chlorpyrifos
Keywords: Workers
Keywords: Toxicology Abstracts; Health & Safety Science Abstracts
Keywords: Data processing
Keywords: Pesticides
Keywords: Statistical analysis
Keywords: Simulation
Keywords: H 1000:Occupational Safety and Health
Keywords: X 24330:Agrochemicals
Keywords: Occupational exposure
Keywords: Occupational health
Date revised - 2011-11-01
Language of summary - English
Pages - 97-112
ProQuest ID - 904463898
SubjectsTermNotLitGenreText - Chlorpyrifos; Workers; Data processing; Statistical analysis; Occupational exposure; Pesticides; Simulation; Occupational health
Last updated - 2012-06-18
British nursing index edition - Annals of Occupational Hygiene [Ann. Occup. Hyg.]. Vol. 55, no. 1, pp. 97-112. Jan 2011.
Corporate institution author - Jin, Yan; Hein, Misty J; Deddens, James A; Hines, Cynthia J
DOI - 26300389-3fcc-46b6-8171csaobj201; 14219590; 0003-4878 English

634. John, Harald; Breyer, Felicitas; Thumfart, Jàrg Oliver; Höchstetter, Hans, and Thiermann, Horst. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for detection and identification of albumin phosphylation by organophosphorus pesticides and G- and V-type nerve agents. 2010; 398, (6): 2677-2691.

Rec #: 53179
Notes: Chemical of Concern: CPY
Abstract: Abstract: Toxic organophosphorus compounds (OPC), e.g., pesticides and nerve agents (NA), are known to phosphylate distinct endogenous proteins in vivo and in vitro. OPC adducts of butyrylcholinesterase and albumin are considered to be valuable biomarkers for retrospective verification of OPC exposure. Therefore, we have detected and identified novel adducts of human serum albumin (HSA) by means of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Pure albumin and plasma were incubated with numerous pesticides and NA of the V- and G-type in different molar ratios. Samples were prepared either by sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by in-gel enzymatic cleavage using endoproteinase Glu-C (Glu-C) or by combining highly albumin-selective affinity extraction with ultrafiltration followed by reduction, carbamidomethylation, and enzymatic cleavage (Glu-C) prior to MALDI-TOF MS analysis. Characteristic mass shifts for phosphylation revealed tyrosine adducts at Y⁴¹¹ (Y⁴⁰¹KFQNALLVRY⁴¹¹TKKVPQVSTPTLVE⁴²⁵), Y¹⁴⁸ and Y¹⁵⁰ (I¹⁴²ARRHPY¹⁴⁸FY¹⁵⁰APE¹⁵³, single and double labeled), and Y¹⁶¹ (L¹⁵⁴LFFAKRY¹⁶¹KAAFTE¹⁶⁷) produced by original NA (tabun, sarin, soman, cyclosarin, VX, Chinese VX, and Russian VX) as well as by chlorpyrifos-oxon, diisopropyl fluorophosphate (DFP), paraoxon-ethyl (POE), and profenofos. MALDI-MS/MS of the single-labeled I¹⁴²-E¹⁵³ peptide demonstrated that Y¹⁵⁰ was phosphylated with preference to Y¹⁴⁸. Aged albumin adducts were not detected. The procedure described was reproducible and feasible for detection of adducts at the most reactive Y⁴¹¹-residue (S/N ≥ 3) when at least 1% of total albumin was labeled. This was achieved by incubating plasma with molar HSA/OPC ratios ranging from approximately 1:0.03 (all G-type NA, DFP, and POE) to 1:3 (V-type NA, profenofos). Relative signal intensity of the Y⁴¹¹ adduct correlated well with the spotted relative molar amount underlining the usefulness for quantitative adduct determination. In conclusion, the current analytical design exhibits potential as a verification tool for high-dose exposure. [graphic removed]
Keywords: Albumin adducts
Berlin/Heidelberg : Springer-Verlag

635. Johnson, H. M.; Domagalski, J. L., and Saleh, D. K. Trends in Pesticide Concentrations in Streamsof the Western United States, 1993-2005. 2011; 47, (2): 265-286.

Rec #: 62239
Keywords: FATE
Notes: Chemical of Concern: CPY
Abstract: Abstract: Trends in pesticide concentrations for 15 streams in California, Oregon, Washington, and Idaho were determined for the organophosphate insecticides chlorpyrifos and diazinon and the herbicides atrazine, s-ethyl diproplythiocarbamate (EPTC), metolachlor, simazine, and trifluralin. A parametric regression model was used to account for flow, seasonality, and antecedent hydrologic conditions and thereby estimate trends in pesticide concentrations in streams arising from changes in use amount and application method in their associated catchments. Decreasing trends most often were observed for diazinon, and reflect the shift to alternative pesticides by farmers, commercial applicators, and homeowners because of use restrictions and product cancelation. Consistent trends were observed for several herbicides, including upward trends in simazine at urban-influenced sites from 2000 to 2005, and downward trends in atrazine and EPTC at agricultural sites from the mid-1990s to 2005. The model provided additional information about pesticide occurrence and transport in the modeled streams. Two examples are presented and briefly discussed: (1) timing of peak concentrations for individual compounds varied greatly across this geographic gradient because of different application periods and the effects of local rain patterns, irrigation, and soil drainage and (2) reconstructions of continuous diazinon concentrations at sites in California are used to evaluate compliance with total maximum daily load targets.
Keywords: pesticides, monitoring, time series analysis, watershed management,
ISI Document Delivery No.: 741LL

636. Johnson, K. E. and Wilgus, T. A. Multiple Roles for Vegf in Non-Melanoma Skin Cancer: Angiogenesis and Beyond.

Rec #: 49869
Notes: Chemical of Concern: CPY
Abstract: ABSTRACT: Vascular endothelial growth factor (VEGF) is known to play a critical role in the development of non-melanoma skin cancers. VEGF is a potent pro-angiogenic factor and it is elevated in mouse and human skin tumors. The use of transgenic and knockout mice has shown that VEGF is essential for tumor development in multiple models of skin carcinogenesis and, until recently, the mechanism of action has been primarily attributed to the induction of angiogenesis. However, additional roles for VEGF have now been discovered. Keratinocytes can respond directly to VEGF, which could influence skin carcinogenesis by altering proliferation, survival, and stemness. In vivo studies have shown that loss of epidermal VEGFR-1 or neuropillin-1 inhibits carcinogenesis, indicating that VEGF can directly affect tumor cells. Additionally, VEGF has been shown to promote tumor growth by recruiting macrophages to skin tumors, which likely occurs through VEGFR-1. Overall, these new studies show that VEGF carries out functions beyond its well-established effects on angiogenesis and highlight the need to consider these alternative activities when developing new treatments for non-melanoma skin cancer. eng

637. Jokanovic, M. Current understanding of the mechanisms involved in metabolic detoxification of warfare nerve agents. 2009; 188, (1): 1-10.

Rec #: 62249
Keywords: REVIEW
Notes: Chemical of Concern: CPY
Abstract: Abstract: This study reviews current understanding of chemical, biochemical and toxicological aspects and mechanisms of metabolism of warfare nerve agents. Among enzymes participating in metabolism of nerve agents the role of A-esterases, serum cholinesterase and carboxylesterases is discussed. This article also discusses other aspects of metabolism of the agents such as protein binding and the role of tissue depots for these compounds. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
Keywords: Organophosphorus, Nerve agents, Soman, Sarin, Tabun, VX
ISI Document Delivery No.: 455CN

638. Joshi, Suresh C; Sharma, Preeti, and Joshi, Suresh C. Male Reproductive Toxicity of Organophosphorous Compounds: a Review. 2011 Aug; 93, (7): 1486-1507.

Rec #: 43229
Notes: Chemical of Concern: CPY
Abstract: Abstract: Fertility is declining in many countries and there has been substantial interest in the potential adverse effects of exposure to environmental hazardous chemicals, including pesticides on male reproduction. Organophosphorous compounds (organophosphates, OP) constitute a heterogeneous category of chemicals specifically designed for the control of pests or plant diseases. OP are known to produce reproductive toxicity, resulting in a decrease in the fertility levels of humans and animals. This review article mainly focused on toxicity of some OP such as acephate, chlorpyrifos, diazinon, dimethoate, fenitrothion, malathion, and monocrotophos especially dealing with reproductive toxicity in males. Furthermore, this review deals with mode of action and clinical syndromes of OP. Considerable lab studies on animals concluded that OP produce adverse effects on male reproductive system.
Keywords: Chemicals
Keywords: Fertility
Keywords: Plant diseases
Keywords: Organophosphates
Keywords: monocrotophos
Keywords: Toxicology Abstracts; Pollution Abstracts
Keywords: Fenitrothion
Keywords: organophosphates
Keywords: Toxicity
Keywords: Malathion
Keywords: Reproductive system
Keywords: Chlorpyrifos
Keywords: Reviews
Keywords: Pesticides
Keywords: Reproduction
Keywords: Dimethoate
Keywords: Pests
Keywords: X 24330:Agrochemicals
Keywords: Diazinon
Keywords: Side effects
Date revised - 2011-09-01
Language of summary - English
Pages - 1486-1507
ProQuest ID - 888097650
SubjectsTermNotLitGenreText - Fertility; Plant diseases; monocrotophos; Toxicity; organophosphates; Fenitrothion; Reproductive system; Malathion; Chlorpyrifos; Reviews; Pesticides; Reproduction; Pests; Dimethoate; Diazinon; Side effects; Chemicals; Organophosphates
Last updated - 2012-03-29
British nursing index edition - Toxicological and Environmental Chemistry [Toxicol. Environ. Chem.]. Vol. 93, no. 7, pp. 1486-1507. Aug 2011.
Corporate institution author - Joshi, Suresh C; Sharma, Preeti
DOI - cb38c0f4-9803-48c4-87e5mfgefd108; 15525825; 0277-2248; 1029-0486 English

639. Juberg, D. R. Differentiating experimental animal doses from human exposures to chlorpyrifos. 2012; 109, (33): E2195-E2195.

Rec #: 62339
Notes: Chemical of Concern: CPY
Abstract: ISI Document Delivery No.: 992VC

640. Juberg, D. R. and Burns, C. J.

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