Appendix 2-5: Rejected ecotox bibliography for Chlorpyrifos



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glutamate-induced toxicity (P < 0.001, ANOVA), indicating that our approach can identify factors that protect or make neurons more susceptible to degeneration.
MESH HEADINGS: Amyotrophic Lateral Sclerosis
MESH HEADINGS: Animals
MESH HEADINGS: Carrier Proteins/genetics/metabolism
MESH HEADINGS: Cell Survival/genetics/physiology
MESH HEADINGS: Cells, Cultured
MESH HEADINGS: Cranial Nerves/metabolism
MESH HEADINGS: Disease Models, Animal
MESH HEADINGS: Female
MESH HEADINGS: Gene Expression Profiling
MESH HEADINGS: Guanine Deaminase/genetics/metabolism
MESH HEADINGS: Insulin-Like Growth Factor II/genetics/metabolism
MESH HEADINGS: Motor Neuron Disease/*genetics/*metabolism/pathology
MESH HEADINGS: Motor Neurons/*metabolism/pathology
MESH HEADINGS: Nerve Degeneration/*genetics/*metabolism/pathology
MESH HEADINGS: Rats
MESH HEADINGS: Rats, Sprague-Dawley
MESH HEADINGS: Rats, Transgenic
MESH HEADINGS: Signal Transduction/genetics
MESH HEADINGS: Spinal Cord/metabolism
MESH HEADINGS: Superoxide Dismutase/genetics/metabolism eng

539. Hee-Yun, K; Jong-Sup, J; Yong-Hoon, K; Hee-Ju, C; So-Young, C; Hwa-Jeong, L; Jae-in, K; Young-Seon, K; Gye-Sun, C; Jae-Chun, C, and Hee-Yun, K. Monitoring of Pesticide Residues in Green Tea Produced in Korea. 2009; 41, (5): 483-489.


Rec #: 45269
Keywords: SURVEY
Notes: Chemical of Concern: CPY
Abstract: Abstract: Herein, we present the results of our investigation of 61 pesticide residues in 100 samples of green teas obtained from Korean markets. Bifenthrin, chlorpyrifos, dicofol, EPN, chlorfenapyr, tebuconazole, cyhalothrin, difenoconazole, and tebufenpyrad were detected in 22 of the 100 green tea samples. The quantity of pesticide residues for bifenthrin was 0.12 ppm (maximum residue limits (MRLs): 0.3 ppm) in one sample, chlorpyrifos was 0.24-0.78 ppm (MRLs: 2.0 ppm) in three samples, dicofol was 1.64-4.19 ppm (MRLs: 50.0 ppm) in two samples, EPN was 0.13 ppm (MRLs: 0.05 ppm) in one sample, chlorfenapyr was 0.01-1.23 ppm (MRLs: 3.0 ppm) in 16 samples, tebuconazole was 0.71 ppm (MRLs: 5.0 ppm) in one sample, cyhalothrin was 0.05-0.3 ppm (MRLs: 2.0 ppm) in five samples, difenoconazole was 0.23 ppm (MRLs: 2.0 ppm) in one sample, and tebufenpyrad was 0.06-0.07 ppm (MRLs: 2.0 ppm) in two samples. More than two pesticide residues were detected in seven samples. All detected pesticide residues (with the exception of EPN) were within the MRLs.
Keywords: Chlorpyrifos
Keywords: Pesticide residues
Keywords: Pesticides
Keywords: Korea, Rep.
Keywords: Health & Safety Science Abstracts
Keywords: tea
Date revised - 2010-01-01
Language of summary - English
Location - Korea, Rep.
Pages - 483-489
ProQuest ID - 21147651
SubjectsTermNotLitGenreText - Korea, Rep.; Pesticide residues; Pesticides; tea; Chlorpyrifos
Last updated - 2011-12-14
British nursing index edition - Korean Journal of Food Science and Technology [Korean J. Food Sci. Technol.]. Vol. 41, no. 5, pp. 483-489. 2009.
Corporate institution author - Hee-Yun, K; Jong-Sup, J; Yong-Hoon, K; Hee-Ju, C; So-Young, C; Hwa-Jeong, L; Young-Seon, K; Gye-Sun, C; Jae-Chun, C
DOI - MD-0011157825; 11292219; 0367-6293 English

540. Hein, Nichole D; Rainier, Shirley R; Richardson, Rudy J; Fink, John K, and Hein, Nichole D. Motor Neuron Disease Due to Neuropathy Target Esterase Mutation: Enzyme Analysis of Fibroblasts From Human Subjects Yields Insights Into Pathogenesis. 2010 Nov 10; 199, (1): 1-5.


Rec #: 43779
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Abstract: Recently, we identified neuropathy target esterase (NTE) mutation as the cause of an autosomal recessive motor neuron disease (NTE-MND). Subsequently, we showed that NTE-MND mutations reduced specific activity (SA) and altered inhibitory kinetics of NTE catalytic domain constructs. Recent preliminary results showed that NTE is expressed in cultured human skin fibroblasts, and others have used mutant forms of neuronal proteins expressed in fibroblasts as biomarkers of neurogenetic diseases. Therefore, the present study was carried out to test the hypothesis that NTE in cultured skin fibroblasts from NTE-MND subjects also exhibit altered enzymological properties assessed by SA and IC50 values of mipafox (MIP) and chlorpyrifos oxon (CPO). NTE SA was reduced to 65% of control (wild-type NTE from commercially obtained fibroblasts) in homozygous M1012V fibroblasts and 59-61% of control in compound heterozygous R890H/c2946_2947InsCAGC fibroblasts. MIP IC50 values were unaffected by the NTE mutations, but the CPO IC50 increased 4.5-fold in homozygous M1012V fibroblasts. Interestingly, markedly reduced NTE SAs (40-43% of control) were observed in fibroblasts from asymptomatic subjects heterozygous for NTE insertion c2946_2947InsCAGC. This insertion is predicted to produce truncated NTE missing the last 235 residues of its catalytic domain. These observations confirm that NTE-MND mutations reduce NTE SA in vitro. Moreover, to the extent observations made in cultured fibroblasts may be generalized to events in the nervous system, lack of correlation between reduced fibroblast NTE SA and the occurrence of NTE-MND in NTE insertion mutation heterozygotes indicates that reduction of NTE SA alone is insufficient to cause MND.
Keywords: Genetics Abstracts; CSA Neurosciences Abstracts; Toxicology Abstracts
Keywords: N3 11023:Neurogenetics
Keywords: Pharmacy And Pharmacology
Keywords: Skin
Keywords: Neuropathy target esterase
Keywords: Enzymes
Keywords: Motor neuron disease
Keywords: biomarkers
Keywords: Fibroblasts
Keywords: Chlorpyrifos
Keywords: Nervous system
Keywords: Kinetics
Keywords: Heterozygotes
Keywords: G 07710:Chemical Mutagenesis & Radiation
Keywords: Neurogenetics
Keywords: X 24330:Agrochemicals
Keywords: Mutation
Date revised - 2011-10-01
Language of summary - English
Pages - 1-5
ProQuest ID - 887395646
SubjectsTermNotLitGenreText - Chlorpyrifos; Nervous system; Skin; Kinetics; Heterozygotes; Neuropathy target esterase; Enzymes; Neurogenetics; biomarkers; Motor neuron disease; Mutation; Fibroblasts
Last updated - 2011-12-13
Corporate institution author - Hein, Nichole D; Rainier, Shirley R; Richardson, Rudy J; Fink, John K
DOI - OB-3b10c861-b5a2-46f4-a886csaobj202; 13819746; 0378-4274 English

541. Hein, Nichole D; Stuckey, Jeanne a; Rainier, Shirley R; Fink, John K; Richardson, Rudy J, and Hein, Nichole D. Constructs of Human Neuropathy Target Esterase Catalytic Domain Containing Mutations Related to Motor Neuron Disease Have Altered Enzymatic Properties. 2010 Jul 1; 196, (2): 67-73.


Rec #: 44079
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Abstract: Neuropathy target esterase (NTE) is a phospholipase/lysophospholipase associated with organophosphorus (OP) compound-induced delayed neurotoxicity (OPIDN). Distal degeneration of motor axons occurs in both OPIDN and the hereditary spastic paraplegias (HSPs). Recently, mutations within the esterase domain of NTE were identified in patients with a novel type of HSP (SPG39) designated NTE-related motor neuron disease (NTE-MND). Two of these mutations, arginine 890 to histidine (R890H) and methionine 1012 to valine (M1012V), were created in human recombinant NTE catalytic domain (NEST) to measure possible changes in catalytic properties. These mutated enzymes had decreased specific activities for hydrolysis of the artificial substrate, phenyl valerate. In addition, the M1012V mutant exhibited a reduced bimolecular rate constant of inhibition (k i) for all three inhibitors tested: mipafox, diisopropylphosphorofluoridate, and chlorpyrifos oxon. Finally, while both mutated enzymes inhibited by OP compounds exhibited altered time-dependent loss of their ability to be reactivated by nucleophiles (aging), more pronounced effects were seen with the M1012V mutant. Taken together, the results from specific activity, inhibition, and aging experiments suggest that the mutations found in association with NTE-MND have functional correlates in altered enzymological properties of NTE.
Keywords: Heat shock proteins
Keywords: Lysophospholipase
Keywords: Pharmacy And Pharmacology
Keywords: Arginine
Keywords: esterase
Keywords: Aging
Keywords: Neuropathy target esterase
Keywords: Enzymes
Keywords: phospholipase
Keywords: Motor neuron disease
Keywords: Hydrolysis
Keywords: Nests
Keywords: Methionine
Keywords: Chlorpyrifos
Keywords: Nucleophiles
Keywords: Motor neurons
Keywords: Histidine
Keywords: Neurotoxicity
Keywords: Hereditary spastic parplegia
Keywords: Degeneration
Keywords: valine
Keywords: X 24330:Agrochemicals
Keywords: Mutation
Keywords: Toxicology Abstracts
Date revised - 2011-12-01
Language of summary - English
Pages - 67-73
ProQuest ID - 913846136
SubjectsTermNotLitGenreText - Lysophospholipase; Heat shock proteins; Arginine; esterase; Neuropathy target esterase; Aging; Enzymes; phospholipase; Hydrolysis; Motor neuron disease; Nests; Methionine; Chlorpyrifos; Nucleophiles; Motor neurons; Histidine; Neurotoxicity; Hereditary spastic parplegia; Degeneration; valine; Mutation
Last updated - 2012-01-05
Corporate institution author - Hein, Nichole D; Stuckey, Jeanne A; Rainier, Shirley R; Fink, John K; Richardson, Rudy J
DOI - OB-bdf80c35-8a28-4681-8244csaobj202; 13202988; 0378-4274 English

542. Hellstrom, A.; Nilsson, M. L., and Kylin, H. Current-use and Organochlorine Pesticides and Polychlorinated Biphenyls in the Biodegradable Fraction of Source Separated Household Waste, Compost, and Anaerobic Digestate. 2011; 86, (1): 60-64.


Rec #: 61439
Keywords: FATE
Notes: Chemical of Concern: CPY
Abstract: Abstract: Several current-use (a parts per thousand currency sign80 ng g(-1) dry weight) and organochlorine pesticides (a parts per thousand currency sign15 ng g(-1) dry weight) and polychlorinated biphenyls (a parts per thousand currency sign18 ng g(-1) dry weight) were found in the biodegradable fraction of source separated household waste, compost, and/or anaerobic digestate. The degradation rates of individual compounds differ depending on the treatment. Dieldrin and pentachloroaniline, e.g., degrade more rapidly than the waste is mineralized and accumulates in the products after all treatments. Many organochlorines degrade at the same rate as the waste and have the same concentrations in the waste and products. Chlorpyrifos degrades slower than the waste and accumulates in all products and ethion during anaerobic digestion. The polychlorinated biphenyls and some pesticides show different degradations rates relative the waste during different processes. Understanding the degradation of the contaminants under different conditions is necessary to develop quality criteria for the use of compost and digestate.
Keywords: Organic waste, Composting, Mesophilic digestion, Thermophilic digestion,
ISI Document Delivery No.: 703RV

543. Heltshe, Sonya L; Lubin, Jay H; Koutros, Stella; Coble, Joseph B; Ji, Bu-Tian; Alavanja, Michael C R; Blair, Aaron; Sandler, Dale P; Hines, Cynthia J; Thomas, Kent W; Barker, Joseph; Andreotti, Gabriella; Hoppin, Jane a; Beane Freeman, Laura E, and Heltshe, Sonya L. Using Multiple Imputation to Assign Pesticide Use for Non-Responders in the Follow-up Questionnaire in the Agricultural Health Study. 2012 Jul; 22, (4): 409-416.


Rec #: 46659
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Abstract: The Agricultural Health Study (AHS), a large prospective cohort, was designed to elucidate associations between pesticide use and other agricultural exposures and health outcomes. The cohort includes 57,310 pesticide applicators who were enrolled between 1993 and 1997 in Iowa and North Carolina. A follow-up questionnaire administered 5 years later was completed by 36,342 (63%) of the original participants. Missing pesticide use information from participants who did not complete the second questionnaire impedes both long-term pesticide exposure estimation and statistical inference of risk for health outcomes. Logistic regression and stratified sampling were used to impute key variables related to the use of specific pesticides for 20,968 applicators who did not complete the second questionnaire. To assess the imputation procedure, a 20% random sample of participants was withheld for comparison. The observed and imputed prevalence of any pesticide use in the holdout dataset were 85.7% and 85.3%, respectively. The distribution of prevalence and days/year of use for specific pesticides were similar across observed and imputed in the holdout sample. When appropriately implemented, multiple imputation can reduce bias and increase precision and can be more valid than other missing data approaches.
Keywords: Inventories
Keywords: USA, North Carolina
Keywords: Statistics
Keywords: Data processing
Keywords: USA, Iowa
Keywords: H 5000:Pesticides
Keywords: Health & Safety Science Abstracts; Risk Abstracts; Toxicology Abstracts
Keywords: Pesticides
Keywords: R2 23060:Medical and environmental health
Keywords: Sampling
Keywords: X 24330:Agrochemicals
Keywords: Environmental Studies
Date revised - 2012-11-01
Language of summary - English
Location - USA, North Carolina; USA, Iowa
Pages - 409-416
ProQuest ID - 1222433307
SubjectsTermNotLitGenreText - Inventories; Statistics; Data processing; Pesticides; Sampling; USA, North Carolina; USA, Iowa
Last updated - 2012-12-06
Corporate institution author - Heltshe, Sonya L; Lubin, Jay H; Koutros, Stella; Coble, Joseph B; Ji, Bu-Tian; Alavanja, Michael C R; Blair, Aaron; Sandler, Dale P; Hines, Cynthia J; Thomas, Kent W; Barker, Joseph; Andreotti, Gabriella; Hoppin, Jane A; Beane Freeman, Laura E
DOI - OB-aa7e000b-a381-475b-8273mfgefd108; 16841568; 1559-0631 English

544. Henderson, J. D.; Glucksman, G.; Leong, B.; Tigyi, A.; Ankirskaia, A.; Siddique, I.; Lam, H.; DePeters, E., and Wilson, B. W. Pyridostigmine bromide protection against acetylcholinesterase inhibition by pesticides. 2012; 26, (1): 31-34.


Rec #: 61459
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Abstract: Pyridostigmine bromide (PB) has been used to protect soldiers from the toxic effects of soman, a chemical warfare agent. Recent research shows that pyridostigmine bromide protects a significant percentage of acetylcholinesterase in isolated human intercostal muscle. Findings presented here indicate that red blood cell acetylcholinesterase is similarly protected by pyridostigmine bromide from the action of diisopropyl fluorophosphate and several organophosphate pesticides including chlorpyrifos-oxon, diazinon-oxon, and paraoxon, but not malaoxon, using the bovine red blood cell as a subject. These findings suggest that pretreatment with PB may protect growers, farmworkers, first responders, and the public, in general, from the effects of selected pesticides. (C) 2011 Wiley Periodicals, Inc. J Biochem Mol Toxicol 26:31-34, 2012; View this article online at wileyonlinelibrary.com. DOI 10:1002/jbt.20410
Keywords: Pyridostigmine Bromide, Acetylcholines- terase, Organophosphate,
ISI Document Delivery No.: 883KX

545. Hern+índez-Borges, Javier; Cabrera, Juan Cabrera; Rodr+¡guez-Delgado, Miguel +üngel; Hern+índez-Su+írez, Estrella M., and Sa+¦co, V+ ctor Gal+ín. Analysis of pesticide residues in bananas harvested in the Canary Islands (Spain). 2009 Mar 1-; 113, (1): 313-319.


Rec #: 5210
Keywords: SURVEY
Notes: Chemical of Concern: CPY
Abstract: In this work, 11 pesticides (ethoprofos, dimethoate, diazinon, malaoxon, chlorpyrifos-methyl, fenitrothion, malathion, chlorpyrifos, fenamiphos, buprofezin and phosmet) were analysed in 57 banana samples taken from the local markets of the Canary Islands (Spain). Analyses were carried out by the QuEChERS approach developed for pesticide residue analysis in food, using gas chromatography (GC) with nitrogenÇôphosphorus detection (NPD). Triphenylphosphate (TPP) was used as internal standard. Recoveries ranged between 67% and 118% with RSD values below 16%. Typical limits of quantification (LOQs) of the method were 0.01Çô0.14 mg/kg, which are below the EU maximum residue limits (MRLs) established for these compounds in bananas. Chlorpyrifos was detected in 50 samples (88%) in the concentration range 0.03Çô0.65 mg/kg, malathion in five samples (8.8%) in the concentration range 0.16Çô0.17 mg/kg, fenitrothion in four samples (7.0%) in the concentration range 0.02Çô0.10 mg/kg and buprofezin in one sample (1.8%) at 0.15 mg/kg. All these values are below the MRLs established for these compounds except for two samples containing fenitrothion. Among the studied pesticides only chlorpyrifos has a high occurrence in the samples. However, the levels of these residues cannot be considered a serious public health problem according to EU regulations. Because of the high occurrence of chlorpyrifos, its distribution between the pulp and the peel was also investigated. Results show that most of the pesticide remains in the peel and that only amounts between 0.07 and 0.12 mg/kg occur in the pulp even at concentrations in the peel as high as 0.87 mg/kg. Gas chromatography/ NitrogenÇôphosphorous detection/ Pesticides/ Bananas/ Monitoring

546. Hern Ndez, F.; Grimalt, S.; Pozo, O. J., and Sancho, J. V. Use of Ultra-High-Pressure Liquid Chromatography-Quadrupole Time-of-Flight Ms to Discover the Presence of Pesticide Metabolites in Food Samples.


Rec #: 78369
Keywords: FOOD
Notes: Chemical of Concern: CPY
Abstract: ABSTRACT: In this paper we illustrate the use of two different methodologies to investigate the presence of pesticide metabolites in parent pesticide-positive food samples, using ultra-high-pressure liquid chromatography coupled to hybrid quadrupole time-of-flight (UHPLC-QTOF) mass spectrometry. First, a common fragmentation pathway between the parent pesticide and its metabolites has been considered to search for metabolites in two positive market samples (imazalil in lemon, chlorpyrifos in grape). Secondly, olive oil samples from field residue trials were used for automated application of comparative software (MetaboLynx), which was used with treated and untreated samples to search for expected and unexpected metabolites of phosmet. One of the main objectives when using these approaches was to avoid the tedious manual searching for potential metabolites within the huge amount of information contained in the total ion chromatogram acquired by TOF MS. The common fragmentation approach applied to TOF MS full-acquisition data, considering an enhanced fragmentation in the collision cell, has allowed the discovery of two metabolites of imazalil (1-[2-(2,4-dichlorophenyl)-2-hydroxyethyl]-1H-imidazole and 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-imidazole) in a lemon positive sample, as well as another two metabolites of chlorpyrifos (chlorpyrifos-oxon and 3,5,6-trichloro-2-pyridinol) in a grape positive sample. Moreover, MetaboLynx application to TOF MS data, without promoting fragmentation, from treated and untreated olive oil samples has been helpful in detecting the metabolite phosmet-oxon. In both strategies, every metabolite detected by TOF MS was confirmed using QTOF and/or triple quadrupole instruments. Accurate masses given by TOF MS together with the valuable information on product ions given by QTOF MS/MS experiments were crucial for the unambiguous identification of metabolites.
MESH HEADINGS: Chlorpyrifos/chemistry/metabolism
MESH HEADINGS: Chromatography, High Pressure Liquid/instrumentation/*methods
MESH HEADINGS: Citrus/chemistry
MESH HEADINGS: Food Contamination/*analysis
MESH HEADINGS: Fungicides, Industrial/chemistry/metabolism
MESH HEADINGS: Humans
MESH HEADINGS: Imidazoles/chemistry/metabolism
MESH HEADINGS: Mass Spectrometry/instrumentation/*methods
MESH HEADINGS: Molecular Structure
MESH HEADINGS: Pesticide Residues/*analysis
MESH HEADINGS: *Pesticides/chemistry/metabolism
MESH HEADINGS: Plant Oils/chemistry
MESH HEADINGS: Software
MESH HEADINGS: Vitis/chemistry eng

547. Hernandez-Hernandez, C. N. A.; Valle-Mora, J.; Santiesteban-Hernandez, A., and Bello-Mendoza, R. Comparative ecological risks of pesticides used in plantation production of papaya: Application of the SYNOPS indicator. 2007; 381, (1-3): 112-125.


Rec #: 61499
Keywords: NO EFFECT,MODELING
Notes: Chemical of Concern: CPY
Abstract: Abstract: Pesticides are used intensively for crop protection in tropical fruit plantations. Assessments of the relative risks posed by pesticides are needed to assist in the development of management plans that minimize ecological impacts. In this study, the risk indicator SYNOPS-2 was used to compare risks to aquatic ecosystems by pesticides commonly used in papaya plantations. Plant interception and spray drift were measured during six applications of three pesticides (chlorothalonil, chloropyrifos, and malathion) using a turbo fan driven sprayer. Plant interception was estimated to be higher (42.6 +/- 12.7%; p=0.04) in late (8-14 months old) than in early (4 months old) trees (20.1 +/- 25.3%). Chlorothalonil concentrations of up to 11.0 mu g L(-1) were found in water from an adjacent ditch after field application. Concentrations of this pesticide (7.4 +/- 4.1 mu g(-1)) in runoff water were also significantly (p < 0.01) higher than those of malathion (2.4 +/- 1.9 mu g L(-1)) and chlorpyrifos (0.8 +/- 0.5 mu g L(-1)). Good correlation between measured and predicted values (r(2)=0.56-0.85, p < 0.01) showed that SYNOPS-2 is able to describe trends in runoff pollution in papaya plantations. Linear equations were obtained in order to correct numerical disagreement between measured and calculated runoff concentrations. An independent test showed a reasonable agreement between measured chlorothalonil concentrations and the predicted values using the proposed equations. Fifteen pesticides used in papaya cultivation were ranked according to their calculated chronic biological risk index. Pesticides with the highest risk index for non-target organisms were: chlorothalonil for algae, lambda cyahalotrin for Daphnia and fish, and malathion for earthworms. Chlorothalonil was the pesticide with the highest exposure level in water and therefore represents a high risk for aquatic life. Results show that SYNOPS-2 can be used as a pesticide risk indicator on papaya and possibly other tropical fruit plantations. (c) 2007 Elsevier B.V. All rights reserved.
Keywords: papaya, pesticide risk indicator, runoff, spray drift, tropical
ISI Document Delivery No.: 187FA

548. Higgins, P. C. and Jarvis, R. A. Chlorpyrifos - The Latest Advance in Controlling Fleas in Dogs and Cats. 1986; 16, 103-(ABS).


Rec #: 110
Keywords: ABSTRACT
Call Number: NO ABSTRACT (CPY)
Notes: Chemical of Concern: CPY

549. Hill, A. J.; Teraoka, H.; Heideman, W., and Peterson, R. E. Zebrafish as a Model Vertebrate for Investigating Chemical Toxicity. 2005; 86, (1): 6-19.


Rec #: 2030
Keywords: REFS CHECKED,REVIEW
Call Number: NO REFS CHECKED (ATZ,CPY,Cu,ES,PAH,Zn,Zn element), NO REVIEW (ATZ,CPY,Cu,ES,PAH,Zn,Zn element)
Notes: Chemical of Concern: ATZ,Al,CPY,Cd,Co,Cu,EPRN,ES,Hg,NYP,Ni,PAH,PRN,Pb,TXP,Zn

550. Hinderliter, Paul M; Price, Paul S; Bartels, Michael J; Timchalk, Charles; Poet, Torka S, and Price, Paul S. Development of a Source-to-Outcome Model for Dietary Exposures to Insecticide Residues: an Example Using Chlorpyrifos. 2011 Oct; 61, (1): 82-92.


Rec #: 39389
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
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