Appendix 2-5: Rejected ecotox bibliography for Chlorpyrifos



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The purpose of this summary is to provide-state-of-the-art review of recent developments of non-mammalian experimental models and their utility in addressing issues pertinent to neurotoxicity (Caenorhabditis elegans and Danio rerio). The synopses by Aschner and Levin summarize how genetic mutants of these species can be used to complement the understanding of molecular and cellular mechanisms associated with neurobehavioral toxicity and neurodegeneration. Next, studies by Sunol and Olopade detail the predictive value of cultures in assessing neurotoxicity. Sunol and colleagues summarize present novel information strategies based on in vitro toxicity assays that are predictive of cellular effects that can be extrapolated to effects on individuals. Olopade and colleagues describe cellular changes caused by sodium metavanadate (SMV) and demonstrate how rat primary astrocyte cultures can be used as predicitive tools to assess the neuroprotective effects of antidotes on vanadium-induced astrogliosis and demyelination. (C) 2010 Elsevier Inc. All rights reserved.
Keywords: Caenorhabditis elegans, Zebrafish, Tissue culture, Neurotoxicity,
ISI Document Delivery No.: 651PI

67. Asensio-Ramos, M; Hernandez-Borges, J; Borges-Miquel, T M; Rodriguez-Delgado, Ma, and Asensio-Ramos, M. Evaluation of Multi-Walled Carbon Nanotubes as Solid-Phase Extraction Adsorbents of Pesticides From Agricultural, Ornamental and Forestal Soils. 2009 Aug; 647, (2): 167-176.


Rec #: 41069
Keywords: CHEM METHODS
Notes: Chemical of Concern: CPY
Abstract: Abstract: A new, simple and cost-effective method based on the use of multi-walled carbon nanotubes (MWCNTs) as solid-phase extraction stationary phases is proposed for the determination of a group of seven organophosphorus pesticides (i.e. ethoprophos, diazinon, chlorpyriphos-methyl, fenitrothion, malathion, chlorpyriphos and phosmet) and one thiadiazine (buprofezin) in different kinds of soil samples (forestal, ornamental and agricultural) using gas chromatography with nitrogen phosphorus detection. Soils were first ultrasound extracted with 10 mL 1:1 methanol/acetonitrile (v/v) and the evaporated extract redissolved in 20 mL water (pH 6.0) was passed through 100 mg of MWCNTs of 10-15 nm o.d., 2-6 nm i.d. and 0.1-10 km length. Elution was carried out with 20 mL dichloromethane. The method was validated in terms of linearity, precision, recovery, accuracy and selectivity. Matrix-matched calibration was carried out for each type of soil since statistical differences between the calibration curves constructed in pure solvent and in the reconstituted soil extract were found for most of the pesticides under study. Recovery values of spiked samples ranged between 54 and 91% for the three types of soils (limits of detection (LODs) between 2.97 and 9.49 ng g super(-1)), except for chlorpyrifos, chlorpyrifos-methyl and buprofezin which ranged between 12 and 54% (LODs between 3.14 and 72.4 ng g super(-1)), which are the pesticides with the highest soil organic carbon sorption coefficient (K sub(OC)) values. Using a one-sample test (Student's t-test) with fortified samples at two concentration levels in each type of soil, no significant differences were observed between the real and the experimental values (accuracy percentages ranged between 87 and 117%). It is the first time that the adsorptive potential of MWCNTs for the extraction of organophosphorus pesticides from soils is investigated.
Keywords: Sorption
Keywords: P 5000:LAND POLLUTION
Keywords: Organic carbon
Keywords: Phosphorus
Keywords: Solvents
Keywords: Malathion
Keywords: Soil
Keywords: Chlorpyrifos
Keywords: Carbon
Keywords: Gas chromatography
Keywords: Economics
Keywords: Pesticides
Keywords: Adsorption
Keywords: Pollution Abstracts
Keywords: Diazinon
Keywords: pH
Keywords: nanotechnology
Keywords: Nitrogen
Date revised - 2009-08-01
Language of summary - English
Pages - 167-176
ProQuest ID - 20761837
SubjectsTermNotLitGenreText - Sorption; Organic carbon; Solvents; Phosphorus; Malathion; Soil; Chlorpyrifos; Carbon; Gas chromatography; Pesticides; Economics; Adsorption; Diazinon; pH; nanotechnology; Nitrogen
Last updated - 2012-03-29
British nursing index edition - Analytica Chimica Acta [Anal. Chim. Acta]. Vol. 647, no. 2, pp. 167-176. Aug 2009.
Corporate institution author - Asensio-Ramos, M; Hernandez-Borges, J; Borges-Miquel, T M; Rodriguez-Delgado, MA
DOI - MD-0010125877; 10258726; 0003-2670 English

68. Ashauer, R. Predicting Effects of Fluctuating or Pulsed Exposure to Pesticides on Aquatic Organisms. 2007: (UMI#C828639).


Rec #: 420
Keywords: NO SOURCE
Call Number: NO SOURCE (CBL,CPY,PCP)
Notes: Chemical of Concern: CBL,CPY,PCP

69. Ashauer, R.; Wittmer, I.; Stamm, C., and Escher, B. I. Environmental Risk Assessment of Fluctuating Diazinon Concentrations in an Urban and Agricultural Catchment Using Toxicokinetic-Toxicodynamic Modeling. 2011; 45, (22): 9783-9792.


Rec #: 55969
Keywords: MODELING
Notes: Chemical of Concern: CPY
Abstract: Abstract: Temporally resolved environmental risk assessment of fluctuating concentrations of micropollutants is presented. We separated the prediction of toxicity over time from the extrapolation from one to many species and from acute to sublethal effects. A toxicokinetic-toxicodynamic (TKTD) model predicted toxicity caused by fluctuating concentrations of diazinon, measured by time-resolved sampling over 108 days from three locations in a stream network, representing urban, agricultural and mixed land use. We calculated extrapolation factors to quantify variation in toxicity among species and effect types based on available toxicity data, while correcting for different test durations with the TKTD model. Sampling from the distribution of extrapolation factors and prediction of time-resolved toxicity with the TKTD model facilitated subsequent calculation of the risk of undesired toxic events. Approximately one-fifth of aquatic organisms were at risk and fluctuating concentrations were more toxic than their averages. Contribution of urban and agricultural sources of diazinon to the overall risk varied. Thus using fixed concentrations as water quality criteria appears overly simplistic because it ignores the temporal dimension of toxicity. However, the improved prediction of toxicity for fluctuating concentrations may be small compared to uncertainty due to limited diversity of toxicity data to base the extrapolation factors on.
Keywords: DAPHNIA-MAGNA, PULSED EXPOSURE, GAMMARUS-PULEX, AQUATIC ECOTOXICOLOGY,
ISI Document Delivery No.: 844OI

70. Assis, C. R. D.; Linhares, A. G.; Oliveira, V. M.; Franca, R. C. P.; Carvalho, E. V. M. M.; Bezerra, R. S.; De Carvalho, and L.B.,Jr. Comparative Effect of Pesticides on Brain Acetylcholinesterase in Tropical Fish. 2012; 441, (0): 141-150.


Rec #: 2570
Keywords: IN VITRO
Call Number: NO IN VITRO (CBF,CBL,CPY,DDVP,DZ,TMP)
Notes: Chemical of Concern: CBF,CBL,CPY,DDVP,DZ,TMP

71. Assis, Caio Rodrigo Dias; Castro, Patricia Fernandes; Amaral, Ian Porto Gurgel; Carvalho, Elba Veronica Matoso Maciel; Carvalho, Luiz Bezerra; Bezerra, Ranilson Souza, and Assis, Caio Rodrigo Dias. Characterization of Acetylcholinesterase From the Brain of the Amazonian Tambaqui (Colossoma Macropomum) and in Vitro Effect of Organophosphorus and Carbamate Pesticides. 2010 Oct 1; 29, (10): 2243-2248.


Rec #: 43839
Keywords: IN VITRO
Notes: Chemical of Concern: CPY
Abstract: Abstract: In the present study, acetylcholinesterase (AChE) from the brain of the Amazonian fish tambaqui (Colossoma macropomum) was partially characterized and its activity was assayed in the presence of five organophosphates (dichlorvos, diazinon, chlorpyrifos, and tetraethyl pyrophosphate [TEPP]) and two carbamates (carbaryl and carbofuran) insecticides. Optimal pH and temperature were 7.0 to 8.0 and 45 degree C, respectively. The enzyme retained approximately 70% of activity after incubation at 50 degree C for 30 min. The insecticide concentration capable of inhibiting half of the enzyme activity (IC50) for dichlorvos, chlorpyrifos, and TEPP were calculated as 0.04 mu mol/L, 7.6 mu mol/L, and 3.7 mu mol/L, respectively. Diazinon and temephos did not inhibit the enzyme. The IC50 values for carbaryl and carbofuran were estimated as 33.8 mu mol/L and 0.92 mu mol/L, respectively. These results suggest that AChE from the juvenile C. macropomum brain could be used as an alternative biocomponent of organophosphorus and carbamate biosensors in routine pesticide screening in the environment.
Keywords: Acetylcholinesterase
Keywords: Carbaryl
Keywords: Q5 01502:Methods and instruments
Keywords: P 6000:TOXICOLOGY AND HEALTH
Keywords: Environmental factors
Keywords: Biosensors
Keywords: Insecticides
Keywords: Enzymatic activity
Keywords: X 24330:Agrochemicals
Keywords: pH effects
Keywords: Toxicology
Keywords: pyrophosphates
Keywords: Dichlorvos
Keywords: Screening
Keywords: Temperature effects
Keywords: Carbofuran
Keywords: N3 11028:Neuropharmacology & toxicology
Keywords: Geochemistry
Keywords: dichlorvos
Keywords: Brain
Keywords: Enzymes
Keywords: carbofuran
Keywords: organophosphates
Keywords: Pesticides (carbamates)
Keywords: ENA 02:Toxicology & Environmental Safety
Keywords: Chlorpyrifos
Keywords: CSA Neurosciences Abstracts; Environment Abstracts; Toxicology Abstracts; Pollution Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality
Keywords: Pesticides
Keywords: Diazinon
Keywords: Colossoma macropomum
Date revised - 2011-03-01
Language of summary - English
Pages - 2243-2248
ProQuest ID - 858424080
SubjectsTermNotLitGenreText - Screening; Insecticides; Geochemistry; Pesticides; Brain; Enzymatic activity; Environmental factors; Toxicology; Temperature effects; Carbofuran; Acetylcholinesterase; Enzymes; Carbaryl; organophosphates; Pesticides (carbamates); Biosensors; Chlorpyrifos; pH effects; Diazinon; pyrophosphates; Dichlorvos; dichlorvos; carbofuran; Colossoma macropomum
Last updated - 2012-06-18
British nursing index edition - Environmental Toxicology and Chemistry [Environ. Toxicol. Chem.]. Vol. 29, no. 10, pp. 2243-2248. 1 Oct 2010.
Corporate institution author - Castro, Patricia Fernandes; Carvalho, Luiz Bezerra; Bezerra, Ranilson Souza
DOI - 45c24da6-c0ec-4f17-9429csamfg201; 14430004; CS1146774; 1552-8618 English

72. Atkins, M. B.; Hsu, J.; Lee, S.; Cohen, G. I.; Flaherty, L. E.; Sosman, J. A.; Sondak, V. K.; Kirkwood, J. M., and Eastern Cooperative Oncology Group. Phase Iii Trial Comparing Concurrent Biochemotherapy With Cisplatin, Vinblastine, Dacarbazine, Interleukin-2, and Interferon Alfa-2b With Cisplatin, Vinblastine, and Dacarbazine Alone in Patients With Metastatic Malignant Melanoma (E3695): a Trial Coordinated by the Eastern Cooperative Oncology Group.


Rec #: 51019
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: COMMENTS: Cites: J Clin Oncol. 2008 Feb 1;26(4):527-34 (medline /18235113)
COMMENTS: Cites: Cancer J Sci Am. 2000 Feb;6 Suppl 1:S11-4 (medline /10685652)
COMMENTS: Cites: J Clin Oncol. 2007 Sep 1;25(25):3802-7 (medline /17761969)
COMMENTS: Cites: Clin Cancer Res. 2006 Apr 1;12(7 Pt 2):2353s-2358s (medline /16609058)
COMMENTS: Cites: Ann Oncol. 2006 Apr;17(4):571-7 (medline /16469753)
COMMENTS: Cites: J Clin Oncol. 2005 Sep 20;23(27):6747-55 (medline /16170182)
COMMENTS: Cites: J Clin Oncol. 1999 Mar;17(3):968-75 (medline /10071291)
COMMENTS: Cites: J Clin Oncol. 1999 Feb;17(2):651-7 (medline /10080611)
COMMENTS: Cites: J Clin Oncol. 1998 Sep;16(9):2921-9 (medline /9738559)
COMMENTS: Cites: J Clin Oncol. 1998 May;16(5):1752-9 (medline /9586888)
COMMENTS: Cites: Cancer J Sci Am. 1997 Dec;3 Suppl 1:S9-15 (medline /9457387)
COMMENTS: Cites: Cancer J Sci Am. 1997 Dec;3 Suppl 1:S16-21 (medline /9457388)
COMMENTS: Cites: J Clin Oncol. 1997 Jul;15(7):2579-88 (medline /9215828)
COMMENTS: Cites: J Clin Oncol. 1994 Aug;12(8):1553-60 (medline /8040667)
COMMENTS: Cites: Clin Cancer Res. 2002 Sep;8(9):2775-81 (medline /12231516)
COMMENTS: Cites: J Clin Oncol. 2002 Apr 15;20(8):2045-52 (medline /11956264)
COMMENTS: Cites: J Clin Oncol. 2002 Mar 15;20(6):1600-7 (medline /11896110)
COMMENTS: Cites: Clin Cancer Res. 2000 Jun;6(6):2201-8 (medline /10873069)
COMMENTS: Cites: J Clin Oncol. 2007 Dec 1;25(34):5426-34 (medline /18048825)
ABSTRACT: PURPOSE: Phase II trials with biochemotherapy (BCT) have shown encouraging response rates in metastatic melanoma, and meta-analyses and one phase III trial have suggested a survival benefit. In an effort to determine the relative efficacy of BCT compared with chemotherapy alone, a phase III trial was performed within the United States Intergroup.
ABSTRACT: PATIENTS AND METHODS: Patients were randomly assigned to receive cisplatin, vinblastine, and dacarbazine (CVD) either alone or concurrent with interleukin-2 and interferon alfa-2b (BCT). Treatment cycles were repeated at 21-day intervals for a maximum of four cycles. Tumor response was assessed after cycles 2 and 4, then every 3 months.
ABSTRACT: RESULTS: Four hundred fifteen patients were enrolled, and 395 patients (CVD, n = 195; BCT, n = 200) were deemed eligible and assessable. The two study arms were well balanced for stratification factors and other prognostic factors. Response rate was 19.5% for BCT and 13.8% for CVD (P = .140). Median progression-free survival was significantly longer for BCT than for CVD (4.8 v 2.9 months; P = .015), although this did not translate into an advantage in either median overall survival (9.0 v 8.7 months) or the percentage of patients alive at 1 year (41% v 36.9%). More patients experienced grade 3 or worse toxic events with BCT than CVD (95% v 73%; P = .001).
ABSTRACT: CONCLUSION: Although BCT produced slightly higher response rates and longer median progression-free survival than CVD alone, this was not associated with either improved overall survival or durable responses. Considering the extra toxicity and complexity, this concurrent BCT regimen cannot be recommended for patients with metastatic melanoma.
MESH HEADINGS: Protocol: CVD protocol
MESH HEADINGS: Adult
MESH HEADINGS: Aged
MESH HEADINGS: Aged, 80 and over
MESH HEADINGS: Antineoplastic Combined Chemotherapy Protocols/administration &
MESH HEADINGS: dosage/adverse effects/*therapeutic use
MESH HEADINGS: Cyclophosphamide/administration &
MESH HEADINGS: dosage
MESH HEADINGS: Dacarbazine/administration &
MESH HEADINGS: dosage
MESH HEADINGS: Disease-Free Survival
MESH HEADINGS: Female
MESH HEADINGS: Humans
MESH HEADINGS: Interferon-alpha/administration &
MESH HEADINGS: dosage
MESH HEADINGS: Interleukin-2/administration &
MESH HEADINGS: dosage
MESH HEADINGS: Kaplan-Meier Estimate
MESH HEADINGS: Male
MESH HEADINGS: Melanoma/*drug therapy/mortality/pathology
MESH HEADINGS: Middle Aged
MESH HEADINGS: Neoplasm Metastasis
MESH HEADINGS: Recombinant Proteins
MESH HEADINGS: Time Factors
MESH HEADINGS: Treatment Outcome
MESH HEADINGS: Vincristine/administration &
MESH HEADINGS: dosage
MESH HEADINGS: Young Adult eng

73. Auta, J.; Ogueji, E. O.; Araoye, P. A.; Adikwu, I. A., and Banke, R. O. K. Acute Toxicity and Behavioural Effects of Chlorpyrifos Ethyl Pesticide to Juveniles of Clarias gariepinus. 2008: 264-272.


Rec #: 430
Keywords: NO SOURCE
Call Number: NO CONTROL (CPY), NO ENDPOINT (CPY)
Notes: Chemical of Concern: CPY

74. AuYeung, W.; Canales, R. A., and Leckie, J. O. The fraction of total hand surface area involved in young children's outdoor hand-to-object contacts. 2008; 108, (3): 294-299.


Rec #: 56079
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Abstract: Information on the fraction of total hand surface area touching a contaminated object is necessary in accurately estimating contaminant (e.g., pesticides, pathogens) loadings onto the hands during hand-to-object contacts. While several existing physical-stochastic human exposure models require such surface area data to estimate dermal and non-dietary ingestion exposure, there are very limited data sets. This paper provides statistical distributions of fractional surface areas (FSAs) for children's outdoor hand contacts. These distributions were constructed by combining information collected from two distinct studies exploring children's activity patterns and quantifying hand contact surface area. Results show that for outdoor contacts with "All Objects", a range of 0.13-0.27 captured median FSAs, while a range of 0.12-0.24 captured time-weighted FSAs. Overall, an FSA of 0.31 captured 80-100% of FSAs involved in each child's outdoor hand contacts, depending upon the object of interest. These values are much lower than the often conservative assumptions of up to 1 (i.e., the entire hand) that researchers currently make regarding FSAs involved in indoor and outdoor contacts [USEPA, 1997. Standard operating procedures (SOPs) for residential exposure assessments. Contract no. 68-W6-0030. < http://www.epa.gov/pesticides/trac/science/trac6a05.pdf >]. (C) 2008 Elsevier Inc. All rights reserved.
Keywords: Dermal exposure, Non-dietary exposure, Hand surface area, Micro-level
ISI Document Delivery No.: 368YR

75. Awkerman, J. A.; Raimondo, S., and Barron, M. G. Estimation of Wildlife Hazard Levels Using Interspecies Correlation Models and Standard Laboratory Rodent Toxicity Data. 2009; 72, (24): 1604-1609.


Rec #: 20
Keywords: MODELING,REFS CHECKED
Call Number: NO MODELING (4AP,CBF,CPY,DCTP,DZ,MCB,PPX,STCH,TMP), NO REFS CHECKED (4AP,CBF,CPY,DCTP,DZ,MCB,PPX,STCH,TMP)
Notes: Chemical of Concern: 4AP,CBF,CPY,DCTP,DZ,EN,EPRN,FNTH,MCB,PPHD,PPX,PRN,STCH,TMP

76. Baas, Jan; Jager, Tjalling; Kooijman, Bas, and Baas, Jan. Understanding Toxicity as Processes in Time. 2010 Aug 15; 408, (18): 3735-3739.


Rec #: 47769
Keywords: REVIEW
Notes: Chemical of Concern: CPY
Abstract: Abstract: Studies in ecotoxicology usually focus on a single end point (typically mortality, growth, or reproduction) at a standardized exposure time. The exposure time is chosen irrespective of the properties of the chemical under scrutiny, but should depend on the organism of choice in combination with the compound(s) of interest. This paper discusses the typical patterns for toxic effects in time that can be observed for the most encountered endpoints growth reproduction and survival. Ignoring the fact that toxicity is a process in time can lead to severe bias in environmental risk assessment. We show that especially ECx values for sublethal endpoints can show very distinct patterns in time. We recommend that the test duration for survival as an endpoint should be extended till the incipient LC50 is observed. Given the fact that toxicity data for single compounds show clear patterns in time, it is to be expected that effects of mixtures will also be strongly dependent on time. The few examples that have been published support this statement.
Keywords: Risk assessment
Keywords: Survival
Keywords: SW 3030:Effects of pollution
Keywords: Population dynamics
Keywords: P 6000:TOXICOLOGY AND HEALTH
Keywords: Environmental factors
Keywords: Toxicity tests
Keywords: Environmental Studies
Keywords: ecotoxicology
Keywords: Ecotoxicology
Keywords: Assessments
Keywords: Exposure
Keywords: environmental assessment
Keywords: R2 23050:Environment
Keywords: X 24300:Methods
Keywords: Testing Procedures
Keywords: Mortality
Keywords: Data processing
Keywords: Environmental assessment
Keywords: AQ 00008:Effects of Pollution
Keywords: Q5 01504:Effects on organisms
Keywords: Toxicity
Keywords: ENA 02:Toxicology & Environmental Safety
Keywords: Risk
Keywords: Risk Abstracts; Environment Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; Toxicology Abstracts
Keywords: Water Pollution Effects
Keywords: Standards
Keywords: Reproduction
Keywords: survival
Keywords: Mortality causes
Date revised - 2011-10-01
Language of summary - English
Pages - 3735-3739
ProQuest ID - 814223853
SubjectsTermNotLitGenreText - Ecotoxicology; Environmental assessment; Survival; Toxicity; Population dynamics; Environmental factors; Toxicity tests; Mortality causes; Risk assessment; Mortality; Data processing; Reproduction; ecotoxicology; environmental assessment; Standards; survival; Testing Procedures; Risk; Assessments; Exposure; Water Pollution Effects
Last updated - 2012-08-02
Corporate institution author - Baas, Jan; Jager, Tjalling; Kooijman, Bas
DOI - OB-40cc3f1b-d186-4990-b59ecsaobj202; 13249917; CS1100398; 0048-9697 English

77. Babina, Kateryna; Dollard, Maureen; Pilotto, Louis, and Edwards, John W. Environmental exposure to organophosphorus and pyrethroid pesticides in South Australian preschool children: A cross sectional study. 2012 Nov 1-; 48, (0): 109-120.


Rec #: 4180
Keywords: HUMAN HEALTH
Notes: Chemical of Concern: CPY
Abstract: Organophosphorus (OP) and pyrethroid (PYR) compounds are the most widely used insecticides. OPs and PYRs are developmental neurotoxicants. Understanding the extent of exposure in the general population and especially in young children is important for the development of public health policy on regulation and use of these chemicals. Presented here are the results of the first investigation into the extent of environmental exposure to neurotoxic insecticides in preschool children in South Australia (SA). Environmental exposure/ Organophosphate/ Pyrethroid/ Neurotoxic insecticides/ Children/ South Australia

78. Babu, V; Unnikrishnan, P; Anu, G; Nair, S M, and Babu, V. Distribution of Organophosphorus Pesticides in the Bed Sediments of a Backwater System Located in an Agricultural Watershed: Influence of Seasonal Intrusion of Seawater. 2011 May; 60, (4): 597-609.


Rec #: 43349
Keywords: FATE
Notes: Chemical of Concern: CPY
Abstract: Abstract: This article focuses on the temporal and spatial distribution of three organophosphorous pesticides-malathion, methyl parathion, and chlorpyrifos-in the sedimentary environment of a backwater ecosystem, Kuttanad backwaters, situated in Kerala, India. Based on salinity distribution, geographic characteristics, and human activities prevailing in the area, the study area was divided into three zones: zone 1 with riverine characteristics, zone 2 with freshwater characteristics during and after the monsoon season and estuarine characteristics during the premonsoon season, and zone 3 with estuarine characteristics. The organophosphorus pesticides in the study area showed the order of enrichment as chlorpyrifos >malathion >methyl parathion. While studying the variations in pesticide concentrations seasonally, higher concentrations were observed during the premonsoon monsoon season, with the concentrations being lower than the detectable level. Sediment characteristics, such as pH, texture, organic carbon, moisture content, etc., had reflective effect on the degradation rates of pesticides. The runoff water from the paddy fields made a larger contribution of pesticide pollution to the study area.
Keywords: India, Kerala, Kuttanad
Keywords: Backwater
Keywords: Degradation
Keywords: Spatial distribution
Keywords: M2 551.468:Coastal Oceanography (551.468)
Keywords: ENA 12:Oceans & Estuaries
Keywords: ISW, India, Kerala
Keywords: Watersheds
Keywords: Spatial Distribution
Keywords: Malathion
Keywords: backwaters
Keywords: spatial distribution
Keywords: Salinity
Keywords: Carbon
Keywords: Organophosphorus Pesticides
Keywords: Agricultural Chemicals
Keywords: Rice fields
Keywords: Marine environment
Keywords: H 5000:Pesticides
Keywords: Salinity effects
Keywords: Pesticide pollution
Keywords: Seasonal variability
Keywords: Methyl parathion
Keywords: Enrichment
Keywords: X 24330:Agrochemicals
Keywords: Salinity distribution
Keywords: pH effects
Keywords: AQ 00001:Water Resources and Supplies
Keywords: Pesticides (organophosphorus)
Keywords: SW 3050:Ultimate disposal of wastes
Keywords: Freshwater environments
Keywords: Sedimentary environments
Keywords: Sediments
Keywords: Chlorpyrifos
Keywords: P 1000:MARINE POLLUTION
Keywords: Pesticides
Keywords: Pesticides in river water
Keywords: Meteorological & Geoastrophysical Abstracts; Health & Safety Science Abstracts; Environment Abstracts; Water Resources Abstracts; Pollution Abstracts; Aqualine Abstracts; Toxicology Abstracts
Keywords: Runoff
Keywords: Parathion
Keywords: Monsoons
Date revised - 2011-06-01
Language of summary - English
Location - India, Kerala, Kuttanad; ISW, India, Kerala
Pages - 597-609
ProQuest ID - 874193277
SubjectsTermNotLitGenreText - Pesticides (organophosphorus); Spatial distribution; Freshwater environments; Watersheds; Sediments; Malathion; Chlorpyrifos; Carbon; Rice fields; Marine environment; Salinity effects; Pesticide pollution; Methyl parathion; pH effects; Runoff; Monsoons; Pesticides in river water; Seasonal variability; Sedimentary environments; Salinity distribution; backwaters; spatial distribution; Degradation; Pesticides; Parathion; Salinity; Organophosphorus Pesticides; Agricultural Chemicals; Backwater; Spatial Distribution; Enrichment; India, Kerala, Kuttanad; ISW, India, Kerala
Last updated - 2012-09-10
British nursing index edition - Archives of Environmental Contamination and Toxicology [Arch. Environ. Contam. Toxicol.]. Vol. 60, no. 4, pp. 597-609. May 2011.
Corporate institution author - Babu, V; Unnikrishnan, P; Anu, G; Nair, S M
DOI - f466c5d7-d862-4dfd-b756csaobj201; 14757491; 0090-4341 English

79. Bagheri, Habib; EsÇÖhaghi, Ali; Es-haghi, Ali, and Mesbahi, Noushin. A high-throughput approach for the determination of pesticide residues in cucumber samples using solid-phase microextraction on 96-well plate. 2012 Aug 31-; 740, (0): 36-42.


Rec #: 5030
Keywords: SURVEY
Notes: Chemical of Concern: CPY
Abstract: A high-throughput solid-phase microextraction (SPME) on 96-well plate together with gas chromatographyÇômass spectrometry (GCÇôMS) was developed for the determination of some selected pesticides in cucumber samples. Pieces with the length of 1.0 cm of silicon tubing were precisely prepared and then coated on the end part of stainless steel wires. The prepared fibers were positioned in a home-made polytetrafluoroethylene (PTFE)-based constructed ninety-six holes block to have the possibility of simultaneous immersion of the SPME fibers into the center of individual wells. Pesticides such as diazinon, penconazol, tebuconazol, bitertanol, malathion, phosalone and chlorpyrifos-methyl were selected for their highly application in cucumber field. The performances of the SPME fibers, such as intra and inter-fibers reproducibility, were evaluated and the results showed a good similarity in extraction yields. A volume of 1 mL of the aquatic supernatant of the cucumber samples was transferred into the 96-well plate and the array of SPME fibers was applied for the extraction of the selected pesticides. The important parameters influencing the whole extraction process including, organic solvent percent, salt addition, dilution factor, stirring rate and extraction time were optimized. The inter- and intra-day RSD% were found to be less than 15.4%. Limits of detection (LOD) and limits of quantification (LOQ) were below 60 and 180 ++g kgęĆ1, respectively. The coefficient of determination was satisfactory (r2 > 0.99) for all the studied analytes. The developed method was successfully applied to the monitoring of several samples gathered from local markets. High-throughput/ 96-Well plate/ Pesticide residues/ Cucumber analysis/ Solid-phase microextraction

80. Baglieri, A. ; Gennari, M.; Arena, M., and Abbate, C. The adsorption and degradation of chlorpyriphos-methyl, pendimethalin and metalaxyl in solid urban waste compost. 2011; 46, (6): 454-460.


Rec #: 56169
Keywords: FATE
Notes: Chemical of Concern: CPY
Abstract: Abstract: To evaluate the feasibility of using compost to prepare substrates for the disposal of pesticide residues, adsorption and degradation studies were carried out on three widely used agricultural pesticides:
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