Antibody Name/Symbol Antibody Description



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antibody Name/Symbol

Antibody Description

Clones/Alternative Names

Chapters

α-1-antichymotrypsin

alpha 1 antichromotrypsin

 

Calcifying Fibrous Tumor

α-1-antitrypsin

alpha 1 antitrypsin

A1AT

Yolk Sac Tumor

α-fetoprotein

alpha 1 fetoprotein

AFP, Z5A06, Clone C3

Ependymoblastoma; Focal Nodular Hyperplasia; Hepatoblastoma; Hepatocellular Carcinoma; Juvenile Granulosa Cell Tumor;

Mesenchymal Hamartoma; Pancreatoblastoma; Sertoli-Leydig Cell Tumors; Teratomas; Yolk Sac Tumor



β-2-microglobulin

 

B2-microglob

Nodular Lymphocyte Predominant Hodgkin Lymphoma

β-catenin

beta catenin; involved in regulation of cell adhesion and in signal transduction through Wnt pathway

B-catenin, CLONE 14, E-5, RB-9035Po, 17C2, 5H10

Adrenal Cortical Adenoma; Adrenal Cortical Carcinoma; Calcifying Fibrous Tumor; Craniopharyngioma; Desmoid Fibromatosis;

Familial Adenomatous Polyposis; Fibroma; Fibromatosis Colli; Gardner Fibroma; Gastrointestinal Stromal Tumor; Hepatoblastoma;

Infantile Fibrosarcoma; Infantile/Juvenile Hyaline Fibromatosis; Inflammatory Myofibroblastic Tumor; Medulloblastoma; Myofibroma and Myofibromatosis; Nodular Fasciitis;

Pancreatoblastoma; Papillary Thyroid Carcinoma; Pilomatricoma; Rhabdoid Tumor; Synovial Sarcoma; Wilms Tumor



β-catenin-nuclear

beta catenin nuclear

 

Desmoid Fibromatosis; Familial Adenomatous Polyposis; Gardner Fibroma; Hemangiopericytoma

β-tubulin

beta tubulin

B-tubulin, TUJ1

Pineal Parenchymal Tumors; Subependymal Giant Cell Tumor

κ light chain

kappa light chain

KAPPA

Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency

λ light chain

lambda light chain

LAMBDA

Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency

ACTH

adrenocorticotropic hormone

 

Adrenal Cortical Adenoma

Actin-HHF-35

actin, muscle (HHF35)

MSA, HHF-35

Hemangiopericytoma; Infantile Fibrosarcoma; Kaposiform Hemangioendothelioma; Mucoepidermoid Carcinoma; Myofibroma and Myofibromatosis; Rhabdomyosarcoma

Actin-sm

actin, smooth muscle

SMA, ASM-1, CGA7, 1A4, HUC1-1

Atypical Teratoid/Rhabdoid Tumor; Fibroma; Fibrous Umbilical Polyp; Gastrointestinal Stromal Tumor; Glomus Tumor;

Hemangioma of Infancy; Hemangiopericytoma; Inclusion Body Fibromatosis; Infantile Fibromatosis; Infantile Fibrosarcoma;

Inflammatory Myofibroblastic Tumor; Mesoblastic Nephroma; Myofibroma and Myofibromatosis; Neurothekeoma; Nodular Fasciitis; Pleomorphic Adenoma;

Sialoblastoma



AE1/AE3

mixture of 2 anticytokeratin clones that detect a variety of both high-and low-molecular weight cytokeratins

 

Adamantinoma; Adrenal Cortical Carcinoma; Chordoma; Desmoplastic Small Round Cell Tumor; Glomus Tumor; Infantile Fibrosarcoma; Medulloblastoma;

Melanotic Neuroectodermal Tumor of Infancy; MiTF/TFE Family Translocation-associated Carcinoma; Neuroendocrine Tumors; Papillary Thyroid Carcinoma;



Pleuropulmonary Blastoma; Rhabdoid Tumor; Secretory Carcinoma; Thymoma

AFP

Alpha 1 fetoprotein

α-fetoprotein, Z5A06, Clone C3

Gingival Granular Cell Tumor of the Newborn; Hepatoblastoma; Pancreatoblastoma; Pineal Parenchymal Tumors; Teratomas

ALK

anaplastic lymphoma kinase 1

ALK1, 5A4, ALKC

Anaplastic Large Cell Lymphoma, ALK+; Calcifying Fibrous Tumor; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Omental Mesenteric Hamartoma

ALK1

anaplastic lymphoma kinase 1

5A4, ALKC

Anaplastic Large Cell Lymphoma, ALK+; Calcifying Fibrous Tumor; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Neuroblastoma and Ganglioneuroblastoma

AMACR

alpha-methylacyl-CoA racemase (AMACR)

13H4, P504S

MiTF/TFE Family Translocation-associated Carcinoma; Wilms Tumor

Androgen receptor

androgen receptor

AR441, F39.4.1, AR-N20, ANDROGEN RE

Gynecomastia Trichoepithelioma

APC

adenomatous polyposis coliprotein

 

Desmoid Fibromatosis; Familial Adenomatous Polyposis; Gardner Fibroma

Aromatase

key enzyme in the byosynthesis of estrogen

 

Gynecomastia

Basic fibroblast growth factor

 

FGF2, BFGF, BASIC FGF

Intravascular Papillary Endothelial Hyperplasia

Bcl-2

B-cell lymphoma 2; suppresses apoptosis in a variety of cell systems

ONCL2, BCL2/100/D5, 124, 124.3

Anaplastic Large Cell Lymphoma, ALK+; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; Fibrous Histiocytoma; Hemangiopericytoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Pediatric Follicular Lymphoma; Synovial Sarcoma; Thymoma; Trichoepithelioma

Bcl-6

B-cell CLL/lymphoma 6

LN22, GI191E/A8, N-3, PG-B6P, P1F6, 3FR-1

Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Pediatric Follicular Lymphoma

BER-EP4

epithelial cell adhesion molecule

AUA1, VU-1D9, EPCAM, C10, HEA125

Trichoepithelioma

BOB1

B-cell OCT-binding protein 1

SC955, BOB.1

Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin; Lymphoma; Primary Mediastinal (Thymic) Large B-cell Lymphoma

C-Kit

C-kit; tyrosine-protein kinase activity

CD117, C-19 (C-KIT), 104D2, 2E4, CKIT, A4502, H300, CMA-767

Desmoid Fibromatosis; Inflammatory Polyps; Mastocytosis

CA9

carbonic anhydrase IX

CAIX, ab1508, M75, NB100-417

MiTF/TFE Family Translocation-associated Carcinoma

Calcitonin

polypeptide hormone produced by parafollicular cells (C cells) of the thyroid

CALBINDIN28

Follicular Adenoma; Medullary Thyroid Carcinoma; Neuroendocrine Tumors; Papillary Thyroid Carcinoma

Caldesmon

actin interacting and calmodulin binding protein found in smooth muscle and other cell types

 

Myofibroma and Myofibromatosis

Calponin

thin filament-associated protein that is implicated in regulation and modulation of smooth muscle contraction

N3, 26A11, CALP, CNN1, SMCC, Sm Calp

Chondromyxoid Fibroma; Hemangiopericytoma; Inclusion Body Fibromatosis; Myofibroma and Myofibromatosis; Pleomorphic Adenoma

Calretinin

29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues

DAK-CALRET, 5A5, CAL 3F5, DC8, AB149

Adrenal Cortical Carcinoma; Juvenile Granulosa Cell Tumor; Sertoli-Leydig Cell Tumors; Synovial Sarcoma; Thecoma-Fibroma

CAM5.2

cytokeratin 8/18 (CAM5.2)

5D3, Zym5.2, 5D3, CAM 5.2, KER 10.11, NCL-5D3

Choroid Plexus Tumors

Carcinoembryogenic antigen

 

CEA-M, mCEA, CEA-B18, CEA-D14, CEAGOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEAGOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65

Medullary Thyroid Carcinoma; Syringoma; Teratomas

CD1a

T-cell surface glycoprotein

JPM30, CD1A, O10, NA1/34

Chondroblastoma; Juvenile Xanthogranuloma; Langerhans Cell Histiocytosis; Thymoma

CD2

T-cell surface antigen, LFA2

271, MT910, AB75, LFA-2

Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/Lymphoma; Mastocytosis; Primary Mediastinal (Thymic) Large B-Cell Lymphoma

CD3

T-cell receptor

F7238, A0452, CD3-P, CD3-M, SP7, PS1

Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; Classical Hodgkin Lymphoma; Desmoplastic Small Round Cell Tumor; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/Lymphoma; Thymoma

CD4

T-cell surface glycoprotein, L3T4

IF6, 1290, 4B12, 1F6, CD04

Acute Myeloid Leukemia; Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; T Lymphoblastic Leukemia/Lymphoma

CD5

T-cell surface glycoprotein Leu1, T1

NCL-CD5, 4C7, 54/B4, 54/F6

Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; Childhood Myelodysplastic Syndrome; T Lymphoblastic Leukemia/Lymphoma; Thymoma

CD7

T-cell antigen precursor Leu 9

272, CD7-272

Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; T Lymphoblastic Leukemia/Lymphoma

CD8

T-cell coreceptor antigen, Leu 2, T-cytotoxic cells

M7103, C8/144, C8/144B

Autoimmune Lymphoproliferative Syndrome; Primary Mediastinal (Thymic) Large B-Cell Lymphoma

CD9

motility-related protein-1 (MRP-1)

72F16, BA-2

Mastocytosis

CD10

neutral endopeptidase

NCL-270, CALLA, neprilysin, neutral endopeptidase, NEP

B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; Hepatocellular Carcinoma; MiTF/TFE Family Translocation-associated Carcinoma; Pancreatoblastoma; Pediatric Follicular Lymphoma; Pleomorphic Adenoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma

CD13

plays role in growth of DC/macrophage progenitors and precursors

 

Acute Myeloid Leukemia; B Lymphoblastic Leukemia/Lymphoma; Childhood Myelodysplastic Syndrome

CD14

coreceptor for lipopolysaccharide binding protein

FMC32

Mastocytosis

CD15

reacts with Reed-Sternberg cells of Hodgkin disease and with granulocytes

VIM-2,3C4, LEU-M1, TU9, VIM-D5, MY1, CBD1, MMA, 3CD1, C3D1, Lewis x, SSEA-1

Anaplastic Large Cell Lymphoma, ALK+; Childhood Myelodysplastic Syndrome; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Nodular Lymphocyte Predominant Hodgkin Lymphoma

CD16

Fc receptor of IgG

 

Childhood Myelodysplastic Syndrome; Mastocytosis

CD19

B-cell antigen

 

B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma

CD20

tumor necrosis factor SF8

BER-H2, KI-1, TNFRSF8

Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency Pediatric Follicular Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/Lymphoma; Thymoma

CD21

CR2, complement component receptor 2, Epstein-Barr virus receptor

IF8

Classical Hodgkin Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma

CD22

B-cell receptor

FPC1, LEU 14

B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma

CD23

Fc ε RII, low-affinity IgE receptor, IGEBF

1B12, MHM6BU38

Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma

CD25

If-2 receptor alpha

2A3, 4C9

B Lymphoblastic Leukemia/Lymphoma; Hemophagocytic Syndrome; Mastocytosis

CD30

tumor necrosis factor SF8

BER-H2, KI-1, TNFRSF8

Anaplastic Large Cell Lymphoma, ALK+; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Langerhans Cell Histiocytosis; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma



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